International Journal of Nutrition
Open Access
Structure Activity Relationship of Xanthones for Inhibition of Cyclin Dependent Kinase 4 from Mangosteen (Garcinia Mangostana L.)
Jun 2019 DOI 10.14302/issn.2379-7835.ijn-19-2845
Jeremy J. JohnsonCorresponding author
The mangosteen fruit is a popular Southeast Asian fruit consumed for centuries. There have been a variety of xanthones isolated from the fruit, bark, roots and leaves with each having unique chemical and physical properties. Previously, the most abundant xanthone α-mangostin has been shown to inhibi…