Journal of Digestive Disorders and Diagnosis
Open Access
Mucosa-Muscular Signaling for Bile-Induced Esophageal Dysmotility. An Experimental Study in Ex-Vivoguinea-Pig Isolated Esophagi
Jun 2016 DOI 10.14302/issn.2574-4526.jddd-16-1101
Fernando A. M. HerbellaCorresponding author
Background/Aims: Esophageal motor abnormalities are frequently found in patients with gastroesophageal reflux disease. The effect of bile in esophageal dysmotility is probably secondary to mucosal signaling to the muscular layer and not a transmural process. This study aims to identify the mucosa-mu…