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Jan 2017 DOI 10.14302/issn.2476-1710.jdt-16-1324
Susanne MeiserCorresponding author
An important step in the validation of disorder-specific etiological models is the examination of the predictive specificity of proposed vulnerability factors. It may advance the understanding of the emergence of comorbidity and the identification of at risk-populations for mental disorders. To enha…
Sep 2026
Massreshaw Assnakew AbebeCorresponding author
Gene therapy is a cancer treatment that is superior to chemotherapy, radiotherapy, and other less selective and specifically harmful forms of treatment. It entails the aberrant replacement, alteration, and deletion of a gene within a normal or healthy copy of a gene. Recent trials have made signific…
Nov 2025 DOI 10.14302/issn.2690-4721.ijcm-25-5786
Darrel Ornelle Elion AssianaCorresponding author
In the Republic of the Congo, tuberculosis (TB) remains a major public health concern. Although the GeneXpert MTB/RIF assay is the WHO-recommended first-line diagnostic test, smear microscopy is still used for treatment monitoring and in facilities where molecular testing is limited. Evaluating the…
Sep 2023 DOI 10.14302/issn.2692-1537.ijcv-23-4660
Saeid Amel JamehdarCorresponding author
SARS-CoV-2 real-time reverse-transcription PCR (rRT-PCR) is the most effective testing system available to combat COVID-19, given the absence of any specific treatment or vaccine. Moreover, numerous SARS-CoV-2 rRT-PCR kits have been approved under emergency-use-authorization (EUA) worldwide. In this…
Feb 2023 DOI 10.14302/issn.2641-5526.jmid-23-4450
Vijay PatherCorresponding author
Acute appendicitis is one of the most common surgical emergencies globally, with a lifetime incidence of 8.6% in men and 6.7% in women. While acute appendicitis should be managed promptly to reduce the morbidity associated with perforated appendicitis, morbidity from negative appendicectomy is simil…
Sep 2022 DOI 10.14302/issn.2692-1537.ijcv-22-4328
Gleim Dias De SouzaCorresponding author
Objectives To evaluate the diagnostic accuracy of chest CT for the diagnosis of COVID-19 associated with the clinical presentation and in relation to the PCR-RT. Sensitivity, specificity, positive predictive value and negative predictive value, gender, age group and degree of lung involvement will b…
Jun 2022 DOI 10.14302/issn.2328-0182.japst-22-4193
Yilkal Tariku BelayCorresponding author
The strategy for safe drug discovery and development has limited clinical success as compared to wasted time and resources annually. This is due to the fact that the results of multiphase preclinical trials are less likely to make an accurate early prediction on the safety of test compounds to progr…
May 2022 DOI 10.14302/issn.2766-8681.jcsr-22-4162
Ling WangCorresponding author
Alveolar-arterial oxygen pressure difference (P(Aa)O2) can reflect pulmonary ability to exchange oxygen; it shows good correlation with the oxygenation index (OI), which is important in diagnosing acute respiratory distress syndrome (ARDS). This study explored the ability of P(Aa)O2 in diagnosing AR…
Aug 2021 DOI 10.14302/issn.2326-0793.jpgr-21-3917
Leonid TarassishinCorresponding author
50 years ago the Enzyme Immunoassay Enzyme-Linked Immunosorbent Assay, mostly known as ELISA was developed. This is a powerful but simple method that is very widely used in the diagnostic practice, as well as in biomedical research. During this time a number of ELISA modification were developed that…
Mar 2021 DOI 10.14302/issn.2575-1212.jvhc-21-3767
Faysal Abdishakur HassanCorresponding author
Antibodies and antibody fragments, especially single-domain antibodies known as nanobodies, are important tools in diagnostics, research, and therapeutics. In a conventional antibody, light and heavy chains contribute to the formation of the antigen binding site. In addition to conventional antibodi…
Oct 2020 DOI 10.14302/issn.2379-7835.ijn-20-3418
Farid E. AhmedCorresponding author
Isolation methods that employ readily-available inexpensive supplies on the open market, which are reliable, as well as economical, such as nucleic acid amplification techniques (NAAT) based on microfluidic technology in low-resource research settings (LRRS) that meets the ASSURED guidelines are ess…
Sep 2020 DOI 10.14302/issn.2575-1212.jvhc-20-3477
Fahim A ShaltoutCorresponding author
A total number of 100 samples from ten random broiler chicken carcasses (breast and thigh) were collected from an automatic poultry slaughtering plant in Ismailia city, Egypt. The mean values of Enterobacteriacae count were 5.9x104±9.7x103 cfu/g and 7.1x 104 ± 1.1x104 cfu/g for chicken breast and th…
Aug 2020 DOI 10.14302/issn.2835-513X.ijl-20-3457
Anju GuptaCorresponding author
PEGylation is a well-established strategy for improving the target specificity, circulation time and stability of liposomes, thereby improving their stealth properties. This brief review provides an insight on the composition of PEGylated liposomes and the characteristics that dictate the functional…
Jun 2020 DOI 10.14302/issn.2379-7835.ijn-19-3123
Farid E. AhmedCorresponding author
Isolation methods that employ readily-available inexpensive supplies on the open market, which are reliable, as well as economical, such as nucleic acid amplification techniques (NAAT) based on microfluidic technology in low-resource research settings (LRRS) that meets the ASSURED guidelines are ess…
Mar 2020 DOI 10.14302/issn.2639-3166.jar-20-3260
Giorgio MasoeroCorresponding author
The management of the inoculation of a plant’s roots, by means of biofertilizers (BF) containing arbuscular mycorrhizal (AM) fungi, is aimed at inducing modifications of the quality of the seeds. It is here shown that a seed-soil treatment can be elicited in the fingerprints of a symbiotic treatment…
Jan 2020 DOI 10.14302/issn.2372-6601.jhor-20-3186
Yassongui Mamadou SekongoCorresponding author
Introduction The anti-HCV RIBA test verifies the presence of anti-HCV serum antibodies detected by the Elisa test. In Côte d'Ivoire, screening for hepatitis C is done exclusively by enzyme immunoassays. In order to reduce the number of HCV positive blood donor exclusions on ELISA, we conducted this…
Dec 2019 DOI 10.14302/issn.2372-6601.jhor-19-3094
Vladimir ZaichickCorresponding author
Prostate specific antigen (PSA) does not provide the high reliability and precision that is required for an accurate screening for prostate cancer (PCa). The aim of our study was to search for a simple, rapid, direct, preferably non-invasive, and highly accurate biomarker and procedure for the scree…
Dec 2019 DOI 10.14302/issn.2690-4829.jen-19-3105
Phillip BrummCorresponding author
Trichoderma reeseiβ-glucosidase (Bgl1) is one of four enzymes demonstrated to act synergistically to degrade cellulose both in vitro and in vivo. Our work attempted to better understand the substrate specificity and potential biotechnological applications of Bgl1. T. reesei Bgl1H cleaves over 80% of…
Nov 2019 DOI 10.14302/issn.2372-6601.jhor-19-3084
Ashraf ElyamanyCorresponding author
Background Identifying biomarkers for early detection of hepatocellular carcinoma (HCC) remains quite challenging. In this study we aimed to estimate the number of TIE2-expressing monocytes (TEMs) cells, which display pro-tumoral activities and are defined as CD14+, TIE2+, and angiopoietin-2; and it…
Apr 2019 DOI 10.14302/issn.2470-0436.jos-19-2693
Sayoko E. MoroiCorresponding author
Given limited knowledge regarding validity of the Titmus vision screener, we sought to compare visual acuity measurements obtained from the Titmus with that from the Snellen chart and assess the validity properties of the Titmus as a screening instrument to detect vision impairment. Visual acuity wa…