Search results for “pharmacology”

About 8 results in articles

Open Access Pub publishes peer-reviewed, free-to-read open-access articles. Showing articles matching pharmacology — open any to read the full text, or download the PDF or XML.

Exploring the Mechanism of Complex Lemon-Angelica Sinensis-Boswellia Essential Oil on Anxiety Disorders with Melasma Through Network Pharmacology and Experimental Validation

Dec 2025
Liping LiuCorresponding author

The incidence rate of melasma is notably high among patients with anxiety disorders. Aromatherapy primarily influences the physiological and psychological states of individuals through the inhalation or application of essential oils, thereby facilitating the treatment or alleviation of various condi…

A Network Pharmacology-Based Strategy For Predicting Therapy Targets Of Beta-Sitosterol In Treating Diabetic Retinopathy

May 2024 DOI 10.14302/issn.2470-0436.jos-23-4493
Kexin SunCorresponding author

Background Beta-Sitosterol (SIT) is an active TCM compound employed to treat diabetic retinopathy (DR). A network pharmacology approach to understanding the active ingredients and the therapeutic mechanisms underlying DR has not been pursued. Methods The potential targets for DM were identified acco…

Transformative Psychopharmacology: the Case of 5-Methoxy-N,N-Dimethyltryptamine

Jan 2019 DOI 10.14302/issn.2574-612X.ijpr-18-2503
Jan M Keppel HesselinkCorresponding author

Since the 2nd part of last century neo-shamanic rituals using mind-altering extracts from plants or animals have become increasingly popular in Europe and the USA. The first rituals coming to the west were based on drinking a special Amazonian tea, Ayahuasca, based on 2 different plants, with active…

The Advantages of Employing the Immune Response Mediated by Immunoglobulins in Preclinical and Clinical Research: An Essential Review

Sep 2026
Yilkal Tariku BelayCorresponding author

Immunoglobulins, commonly known as antibodies, are glycoprotein molecules present on B lymphocytes and within the bloodstream. They are essential components of the immune response, as they detect the harmful molecules of test compounds and stimulate the immune system to manifest proportional counter…

Efficacy and Safety of Lercanidipine Combination in Hypertensive Patients

Dec 2025 DOI 10.14302/issn.2329-9487.jhc-25-5778
Manolis S KallistratosCorresponding author

Calcium channel blockers (CCBs) are widely used for the treatment of arterial hypertension, but they differ in terms of pharmacology, tolerability, and pleiotropic actions. Lercanidipine, a highly lipophilic third generation dihydropyridine, reduces blood pressure (BP) effectively as monotherapy and…

Structure Activity Relationship of Xanthones for Inhibition of Cyclin Dependent Kinase 4 from Mangosteen (Garcinia Mangostana L.)

Jun 2019 DOI 10.14302/issn.2379-7835.ijn-19-2845
Jeremy J. JohnsonCorresponding author

The mangosteen fruit is a popular Southeast Asian fruit consumed for centuries. There have been a variety of xanthones isolated from the fruit, bark, roots and leaves with each having unique chemical and physical properties. Previously, the most abundant xanthone α-mangostin has been shown to inhibi…

Comparative Study of Hypolipidemic Effects of Momordica Charantia (Karela) with Atorvastatin in Fat Fed Rats

Nov 2017 DOI 10.14302/issn.2576-9383.jhhr-17-1816
Abu Syed Md. MosaddekCorresponding author

Background: Disorders of lipid metabolism are manifested by elevation of the plasma concentration of the various lipid and lipoprotein fractions and the result, predominantly cardiovascular diseases. Lipid research clinic’s coronary primary prevention trial has provided useful information on the red…

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