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Nov 2024 DOI 10.14302/issn.2690-4829.jen-24-5291
Xiaotang WangCorresponding author
The perpendicular orientation of the proximal alpha helix to the heme plane in chloroperoxidase (CPO) maximizes the influence of its intrinsic helix dipole that has been shown to reduce the “push-effect”, thereby increasing the heme redox potential and fine-tuning the catalytic capabilities of CPO.…
Jul 2021 DOI 10.14302/issn.2577-2279.ijha-21-3869
Juli JainCorresponding author
Rotenone is well known environmental neurotoxin used to induce Parkinson’s disease (PD) model. Numerous studies are investigated its toxicity on the brain but few studies are available that examined its toxicity on the liver and kidney. Therefore, the main aim of the present work was to explore the…
Mar 2021 DOI 10.14302/issn.2471-2140.jaa-21-3747
Snehasis JanaCorresponding author
A proprietary formulation was designed that consisted minerals (zinc, magnesium, iron, calcium, selenium, and copper), vitamins (pyridoxine HCl, cyanocobalamin, ascorbic acid, and cholecalciferol), Panax ginseng extract, and cannabidiol isolate. The study was aimed to assess the potential of the nov…
Feb 2021 DOI 10.14302/issn.2471-2140.jaa-21-3704
Snehasis JanaCorresponding author
The aim of the study was to evaluate the antioxidant potential of Biofield Energy Healing (the Trivedi Effect®) based test formulation using TNBS-induced colitis animal model. Each ingredient of the test formulation was divided into two parts. One part was denoted as the control without any Biofield…
Dec 2020 DOI 10.14302/issn.2835-513X.ijl-20-3247
Ghada Z A SolimanCorresponding author
Hypercholesterolemia plays an important role in atherosclerosis and cardiovascular diseases (CVD) that represent one of the greatest worldwide medical problems nowadays. Recently, an increased attention/ interest for natural antioxidant/ hypercholesterolemia as WG/WGO is increasing. Wheat germ/ Whea…
Jun 2020 DOI 10.14302/issn.2691-8862.jvat-20-3417
Georges TetoCorresponding author
Background Decreased antioxidant ability is one of the worsening conditions in AIDS.We aimed to evaluate total antioxidant ability among others, and their variation in HIV infected patients following their CD4+T cells count and viral load, in a context of new ART scarcity in most LMICs. Material and…
Jan 2020 DOI 10.14302/issn.2690-4829.jen-19-3127
P.A.GhazaryanCorresponding author
Hematology center after prof. R.H.Yeolyan MH RA
The antioxidant and membrane resistant peculiarities of a new derivative (2-cyan-3,4,4-trymethil-2-buten-4-olyd - CTBO) of cyan containing unsaturated lactones have been studied in membranes of hepatocytes with Sarcoma-45 1. The results of our previous research 123 showed significant changes of phos…
Oct 2019 DOI 10.14302/issn.2574-450X.jom-19-2852
EH RadwanCorresponding author
Obesity can be defined as a condition of abnormal or excess fat accumulation in adipose tissue, to the extent that health may be impaired. Fennel is one of the oldest spice plants which widely grows in arid and semi-arid and due to its economic importance and pharmaceutical industry usage. This plan…
Mar 2019 DOI 10.14302/issn.2379-7835.ijn-19-2677
Martin GrootveldCorresponding author
Objectives: Sunflower oil (SFO) is regularly employed for cosmetic, emollient and food frying purposes, the latter representing its foremost use globally. Therefore, full investigations of the molecular composition and quality of SFO products are a major requirement. In this study high-field 1H NMR…
Mar 2018 DOI 10.14302/issn.2575-1212.jvhc-18-2013
Amal A HalawaCorresponding author
Lipopolysaccharide (LPS) is a component of the outer membrane of gram negative bacteria. LPS challenging allows switching transcription of proinflammatory cytokines on via over stimulation of Toll-like receptors (TLRs) signaling pathway with subsequent pathogenic inflammatory response. We investigat…
Dec 2017 DOI 10.14302/issn.2641-7669.ject-17-1789
M.E.Abdel-Salam OmarCorresponding author
Departments of Toxicology and Narcotics
We aimed to study the effect of buspirone, an anxiolytic drug and 5-HT1A agonist on liver injury induced by carbon tetrachloride (CCl4) in rats. Rats were orally treated with CCl4 (2.8 mL/kg in olive oil) along with buspirone at 10, 20 or 30 mg/kg once daily starting with CCl4 and for one week there…
Oct 2017 DOI 10.14302/issn.2576-6694.jbbs-17-1742
Saber A. SakrCorresponding author
Introduction: Cyclophosphamide (CPA) is an anticancer drug .Fennel (Foeniculum vulgare Mill) essential oil is a traditional medicine used against many diseases. Aim. The present work studied the effect of fennel oil against testicular damage and oxidative stress induced by the anticancer drug, cyclo…
Aug 2017 DOI 10.14302/issn.2471-2140.jaa-17-1541
Zhi YuCorresponding author
In the present study, we investigated the chemical compositions, in vitro antioxidant and in vivo hepatoprotective activities of two tea polysaccharides (TPS), which were extracted from two different tea cultivars, Yingshuang (Camellia Senesis, T01) and Yunnan Dayezhong (Camellia Senesis, T09). Comp…
Jul 2017 DOI 10.14302/issn.2639-1716.jn-17-1495
Michael J GonzalezCorresponding author
Diets high in unsaturated fatty acids, especially those containing high levels of linoleic acid, e.g., corn oil, enhance mammary gland tumorigenesis in experimental animals. In contrast, diets high in long-chain polyunsaturated fatty acids such as eicosapentaenoic (EPA) and docosahexaenoic (DHA), e.…