Journal of Hypertension and Cardiology
Open Access
Human Myxomatous Mitral Valves Exhibit Focal Expression of Cartilage-Related Proteins
Jan 2013 DOI 10.14302/issn.2329-9487.jhc-12-102
Carla M. R. LacerdaCorresponding author
Background: Heart valves share developmental signaling pathways with cartilage and bone. While calcific aortic valve disease (CAVD) has been associated with valve calcification and stenosis, suggestive of osteogenesis, myxomatous mitral valve disease (MMVD) is characterized by net matrix degradation…