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Jun 2024 DOI 10.14302/issn.2998-4785.ijne-24-5138
Raúl IseaCorresponding author
The work emphasizes the need for additional research to create novel biomarkers based on the use of microRNAs as a less invasive and precise diagnostic technique for identifying diseases in newborns.
May 2024 DOI 10.14302/issn.2379-7835.ijn-24-5111
Raúl IseaCorresponding author
The purpose of this work is to emphasize the possible benefits of a microRNA-based diet in reducing the negative effects of a number of diseases, such as cancer, diabetes mellitus, obesity, hypertension, chronic respiratory conditions, and others.
Mar 2024 DOI 10.14302/issn.2572-3030.jcgb-24-4970
Sarah DegenhardtCorresponding author
Melanoma treatment has improved significantly with the development of immune checkpoint inhibition (ICI), which has greatly enhanced the survival rates of patients with metastatic melanoma. However, a significant number of patients do not respond well to ICI treatment and experience progression. Thi…
Oct 2020 DOI 10.14302/issn.2379-7835.ijn-20-3418
Farid E. AhmedCorresponding author
Isolation methods that employ readily-available inexpensive supplies on the open market, which are reliable, as well as economical, such as nucleic acid amplification techniques (NAAT) based on microfluidic technology in low-resource research settings (LRRS) that meets the ASSURED guidelines are ess…
Jun 2020 DOI 10.14302/issn.2379-7835.ijn-19-3123
Farid E. AhmedCorresponding author
Isolation methods that employ readily-available inexpensive supplies on the open market, which are reliable, as well as economical, such as nucleic acid amplification techniques (NAAT) based on microfluidic technology in low-resource research settings (LRRS) that meets the ASSURED guidelines are ess…
Feb 2019 DOI 10.14302/issn.2471-7061.jcrc-18-2526
Farid E. AhmedCorresponding author
There is currently no validated micro(mi)RNA diagnostic stool test to screen for colon cancer (CC) on the market because of the complexity of fecal density, vulnerability of stool to daily changes, and the presence of three sources of miRNAs in stool (cell-free from fecal homogenates, exsosomal miRN…
May 2018 DOI 10.14302/issn.2690-4829.jen-18-2048
Wei TangCorresponding author
Rooting of cuttings is very important for production of economically important plants. We produced thousands of plantlets in Taxus chinensisvar. mairei using the technology of rooting of cuttings and identified two types of rooted cuttings, one with low rate of root formation and another with high r…
Jun 2017 DOI 10.14302/issn.2329-9487.jhc-17-1536
Md. Kamrul HossainCorresponding author
Over the last few decades, many research works highlighted the role of miRNAs on cardiac diseases. Ischaemic heart disease (IHD) or coronary heart disease is a condition that is mainly caused by atherosclerosis. It has been established that microribonucleic acids regulate many factors that are invol…
Jan 2016 DOI 10.14302/issn.2574-4372.jesr-15-768
James E. TroskoCorresponding author
The human OCT4 gene encodes a transcription factor that maintains pluripotency and self-renewal in Embryonic Stem (ES) cells. This gene generates several known transcripts by alternative promoter and alternative splicing (OCT4A, OCT4B and OCT4B1). Even though OCT4A is the main isoform responsible fo…
Oct 2015 DOI 10.14302/issn.2329-9487.jhc-15-677
Ravindra KolheCorresponding author
The aim of this review is to compile our understanding of microRNA (miRNA) and its significance in Hypertension (HTN) pathophysiology. The wide spectrum of health disparity is one of the reasons for the dominance of HTN in humans for decades. We are striving hard to understand these variations, and…
May 2015 DOI 10.14302/issn.2572-3030.jcgb-14-495
Ashraf KhanCorresponding author
Thyroid carcinomas encompass a wide spectrum ranging from differentiated thyroid carcinoma (DTC) to poorly differentiated (PDC) and anaplastic thyroid carcinoma (ATC). DTC of both follicular (FTC) and papillary (PTC) types can progress to PDC and AC. The aim of our study was to evaluate if there is…
Jun 2024 DOI 10.14302/issn.2374-9431.jbd-24-5077
Raúl IseaCorresponding author
Dengue is a global arbovirus disease primarily carried by Aedes aegypti and Aedes albopictus mosquitoes. It has four serotypes (DENV1, DENV2, DENV3, and DENV4) and is classified into distinct genotypes. The epidemic is complicated by immunological interactions and viral lineage turnover. Neurologica…
Mar 2021 DOI 10.14302/issn.2329-9487.jhc-21-3742
Tesfaye SisayCorresponding author
Cardiovascular disease is actually a major cause of mortality, illness and hospitalization worldwide. Several risk factors have been identified that are strongly associated with the development of cardiovascular disease. Public prevention strategies have relied predominately on managing environmenta…
Jan 2021 DOI 10.14302/issn.2470-5020.jnrt-20-3619
Keping ChenCorresponding author
Circular RNAs (circRNAs) are recently rediscovered eukaryotic molecules that form a covalently closed-loop structure through a special type of alternative splicing known as backsplicing. These closed-loop structures are highly stable and resistant to RNase degradation, and are thereby expressed in a…
Sep 2019 DOI 10.14302/issn.2574-450X.jom-19-3001
Sikandar Hayat KhanCorresponding author
Gene therapy has entered a new era with the dawn of CRISPR/Cas9 technology which though were always available in nature but rediscovered to tame into a real-tlife genome editing tool. With the modernization upsurge and changes in ways the “homo sapiens” survived on this planet from hunger to current…
Mar 2019 DOI 10.14302/issn.2379-7835.ijn-19-2578
Farid E. AhmedCorresponding author
We present below a mechanistic cellular and molecular approaches for the development of Anti-Inflammatory biomarkersof Probiotic Bacteria in Fermented Foods. Probiotics are live microorganisms that promote human health by counteracting the noxious toxic gut microflora in human intestine, by modulati…
Sep 2018
Riccardo Di GianfilippoCorresponding author
MicroRNAs are short sequences of non-coding RNAs crucial in regulation of cell development, proliferation and differentiation. Some of them showed to be related with the expression of osteogenic genes. Aim of the present review was to evaluate the biological effects of titanium implant surfaces acti…
Mar 2016 DOI 10.14302/issn.2474-3585.jpmc-15-757
Hong LiuCorresponding author
Xijing Hospital of Digestive Diseases, Xijing Hospital, Fourth Military Medical University, Xi'an, 710032,Shaanxi Province, China
Objective: MicroRNAs are involved in the onset, progression and dissemination of esophageal cancer, and they may be useful as prognostic biomarkers. This study aims to evaluate the relation of miR-21 expression and the prognosis of esophageal cancer patients. Methods: In this study, a meta-analysis…