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The impact of the environment on the development of non-communicable chronic diseases has gained prominence in recent years. In this context, a new chemical exposure assessment strategy is needed that is capable of revealing multiple exposures, as well as reflecting the cumulative interaction betwee…
A concise review of autoimmune disease etiology emphasizes genetic susceptibility, inflammatory pathways, and environmental exposures. It points to systems approaches for risk stratification and prevention with illustrative examples.
Genetics alone cannot thoroughly expound the environmental impact on the molecular complexity of the endocrine system. Epigenetic-induced alteration in gene expression has emerged as a way in which environmental compounds may exert endocrine effects. The environmental compounds that interfere with n…