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Mar 2024 DOI 10.14302/issn.2689-4602.jes-24-4956
B.F. ChadovCorresponding author
A new type of mutations-dominant lethals with a facultative manifestation -were discovered in D. melanogaster in 2000. These mutations were named conditional mutations. Under restrictive genetic conditions, the mutations manifest themselves as dominant lethals, whereas dominant lethality disappears…
Nov 2021 DOI 10.14302/issn.2641-4538.jphi-21-3993
Oluwatoyin Adenike Adeyemo-SalamiCorresponding author
Chlorogenic acid (CA), abundantly found in green coffee beans, is a phenolic compound with antioxidant and anti-inflammatory properties amongst others. Exposure to rotenone, a natural pesticide, induces Parkinsonism (a type of neurodegeneration) through the induction of mitochondria dysfunction and…
Jun 2021 DOI 10.14302/issn.2689-4602.jes-21-3868
Jeffrey O. HendersonCorresponding author
Hox genes, their conserved derivatives, and the pathways responsible for their expression have been extensively studied in the fruit fly, Drosophila melanogaster;the experimentation done in the Drosophila model system has given developmental biologists tools to better understand the role and signifi…
Feb 2019 DOI 10.14302/issn.2689-4602.jes-18-2431
Boris F ChadovCorresponding author
The existing hypotheses on speciation rely on Mendelian genes and mutations in them. However, genome-wide sequencing demonstrates that the Mendelian genes account less than one-tenth of the entire genome DNA. This means that a greater part of the genome has not yet been subject to large-scale evolut…