Journal of New Developments in Chemistry
Open Access
Validated Analytical Spectrofluorimetric Method for Quantitation of Diphenhydramine HCl in Commercial Dosage Forms
Aug 2018 DOI 10.14302/issn.2377-2549.jndc-18-2220
Syed Najmul Hejaz AzmiCorresponding author
Diphenhydramine HClis a weakly fluorescent drug having tertiary amine group forming ion pair complex with eosin Y in dichloromethane at pH 5 in disodium hydrogen phosphate-citric acid buffer solution. The complex formation was the basis for the development of new analytical method for determination…