Search results for “differentiation”

About 25 results in articles

Open Access Pub publishes peer-reviewed, free-to-read open-access articles. Showing articles matching differentiation — open any to read the full text, or download the PDF or XML.

Use of Stem Cell Growth and Differentiation Factors (Scdsf) in Central Vertigo

Oct 2026 DOI 10.14302/issn.2379-8572.joa-26-6454
Giorgia GrappeggiaCorresponding author

The clinical use of SCDSF factors in neuro-degenerative pathologies offers a potential therapeutic opportunity. Our observational study aims to evaluate its efficacy in patients affected by Central Vertigo1. A case series divided into two subgroups, all affected by non-migrainous central vertigo, wa…

Stem Cell Differentiation Stage Factors (SCDSFs) Taken from Zebrafish Embryo during Organogenesis and their Role as Epigenetics Regulators able to Reverse Neurosensory Hearing Loss

Feb 2022 DOI 10.14302/issn.2379-8572.joa-22-4072
Pier Mario BiavaCorresponding author

This translational paper discusses differentiation‑stage factors from zebrafish embryos as epigenetic regulators with potential to reverse neurosensory hearing loss. It outlines experimental evidence, delivery concepts, and research gaps.

Rbm45 Phylogenetics, Protein Domain Conservation, and Gene Architecture in Clade Metazoa

Mar 2024 DOI 10.14302/issn.2689-4602.jes-24-4982
Jeffrey O. HendersonCorresponding author

Mammalian Rbm45 is predominately expressed in neuronal tissue and is integral in brain development and neuronal differentiation under physiological conditions. Dysregulation of Rbm45 has been strongly associated with neurodegenerative disorders in humans and can drive hepatocellular carcinoma throug…

The Importance of Mental Functions and Autobiographical Memory in the Development of Identity and Life Story in Adolescence: Their Role in Preventing Identity Diffusion, Aggressiveness And Depression Among Adolescents

Feb 2024 DOI 10.14302/issn.2643-6655.jcap-24-4898
Lucia SeriCorresponding author

The structuring of one’s own identity is a fundamental and demanding evolutionary task of adolescence. The positive resolution of this task, that is the acquisition of a healthy and integrated identity, is closely linked to adolescents’ ability to develop one’s own Life Story, namely an internalized…

A Study of Methods of Sample Collection and Identification in Uroscopy

Nov 2023
Md. Khursid Alam AnsariCorresponding author

Uroscopy is the first documented laboratory test in medicine and is a fundamental diagnostic tool in the Unani system of medicine. Proper sample collection, handling, and identification are important to insure valid results in uroscopy.There are certain do’s and don’ts about the sampling mentioned i…

Dual Energy Computed Tomography and Effect on the Management of Uric Acid Renal Calculi

Mar 2023 DOI 10.14302/issn.2766-8630.jrnm-22-4093
AJ JahangiriCorresponding author

Attenuation differences from 2 x-ray sources allow differentiation and characterization of stone types with similar radiation dose compared to single-energy CT scan. The difference is shown in colours, allowing preoperative prediction and management of stones. We determined the effect of DECT-KUB on…

Distinguish Thyroid Malignant from Benign Alterations using Trace Element Contents in Nodular Tissue determined by Neutron Activation and Inductively Coupled Plasma Mass Spectrometry

Apr 2022 DOI 10.14302/issn.2689-5773.jcdp-22-4123
Vladimir ZaichickCorresponding author

Background Thyroid benign (TBN) and malignant (TMN) nodules are a common thyroid lesion. The differentiation of TMN often remains a clinical challenge and further improvements of TMN diagnostic accuracy are warranted. The aim of present study was to evaluate possibilities of using differences in tra…

A Theory on the Impact of Copper and Micronutrients Against COVID-19 in Humans

Nov 2021 DOI 10.14302/issn.2690-4837.ijip-21-4015
Caitlin A. Connor DAOM PGDip AMP EHP-CCorresponding author

Copper (Cu) has a strong impact on the function of the immune system through several different pathways. These impacts include helping the function of monocytes, neutrophils, and macrophages, and enhancing Natural Killer cells’ activities. Cu also has a role in antimicrobial properties and inflammat…

Anthropometric Study of Nasal Index Among the Youth of Madheshis Community of Nepal

Nov 2021 DOI 10.14302/issn.2577-2279.ijha-21-3925
Surendra Kumar SahCorresponding author

Introduction The nose is one of the important component of the face which is considered as the major clue for the ethnic origin. The proportion of the nose is determined on the same principal as that of the skull.The external nose extends the nasal cavities onto the front of the face and positions t…

Six Fractal Codes of Biological Life Unifying ATOMS, WAVES and INFORMATION: Perspectives in Exobiology, Cancers Basic Research and Artificial Intelligence Biomimetism Decisions Making

Oct 2021 DOI 10.14302/issn.2641-5526.jmid-21-3900
Jean-claude PerezCorresponding author

In this theoretical discovery of a law of Life, there is MATHEMATICS (Geometry, Bits and Numbers) that UNIFY 3 universes as complementary as ATOMIC MASS, WAVES, and INFORMATION (DNA, RNA and Amino Acids). The discovery of a simple numerical formula for the projection of all the atomic mass of life-s…

Elasticity Profile of Skin, Neuronal, Cardiac, and Skeletal Muscle Cells after Treatment with the Biofield Energy Healing-Based Proprietary Test Formulation

Jul 2021 DOI 10.14302/issn.2576-6694.jbbs-21-3819
Snehasis JanaCorresponding author

The present study aimed to evaluate the effect of the Trivedi Effect®- Biofield Energy Treated/Blessed Test formulation/item (TI) composed of minerals (magnesium, zinc, copper, calcium, selenium, and iron), vitamins (ascorbic acid, pyridoxine HCl, alpha tocopherol, cyanocobalamin, and cholecalcifero…

Study of Hypercoagulability in Patients with Acute Leukaemia in the Hematology Department of Teaching Hospital of Yopougon (Abidjan)

Mar 2020 DOI 10.14302/issn.2372-6601.jhor-20-3235
Mahawa Sangaré-BambaCorresponding author

Introduction Acute leukaemia are the clonal and malignant proliferation of immature hematopoietic cells (blast), blocked in their differentiation process. There is an interaction between cancer cells and the clotting process. This could be the expression of Tissue Factor (TF) on the surface of tumor…

Long Non-Coding RNAs Emerging as Potential Epigenetic Biomarkers for Tobacco and/or Alcohol-Induced Head and Neck Cancer

Aug 2019 DOI 10.14302/issn.2572-3030.jcgb-19-2973
Mausumi BharadwajCorresponding author

Head and Neck cancer (HNC) is one of the most prevalent and lethal cancer globally. The incidence of tobacco-induced HNC is gradually increasing in low and middle income countries. Among the various causative factors associated with HNCs, tobacco and alcohol play synergistic effect and are frequentl…

Oligodendrocytes Development and Wnt Signaling Pathway

Oct 2018 DOI 10.14302/issn.2577-2279.ijha-18-2407
Hui FuCorresponding author

Oligodendrocytes are specialized glial cell in central nervous system (CNS) responsible for the formation of myelin sheath around the axon. Oligodendrocyte proliferation and differentiation is regulated by Wnt signaling pathway, at various stages. However, different study groups have described contr…

The Use of Mirnas as Activators of Dental Implant Surfaces, A Review

Sep 2018
Riccardo Di GianfilippoCorresponding author

MicroRNAs are short sequences of non-coding RNAs crucial in regulation of cell development, proliferation and differentiation. Some of them showed to be related with the expression of osteogenic genes. Aim of the present review was to evaluate the biological effects of titanium implant surfaces acti…

Molecular and Cell Biological Considerations in the Initiation and Development of Sporadic Non-Hereditary Solid Cancers  

Aug 2018 DOI 10.14302/issn.2572-3030.jcgb-18-2183
Vladimir F. NiculescuCorresponding author

This paper reviews the state of cancer research in the post-mutation era. It presents cancer as a highly complex disease viewed differently by scientists from various research fields. Histopathologists considered cancer as a disease of cell differentiation, cancer cell biologists overestimated the c…

Integrated Characterization of Cuban Germplasm of Cocoyam (Xanthosoma Sagittifolium (L.) Schott)

Jun 2018 DOI 10.14302/issn.2641-9467.jgrc-18-2041
Marilys D. Milián JiménezCorresponding author

The present study aims at integrating the characterization studies conducted on the Cuban germplasm collection of Xanthosoma sagittifolium (Araceae) preserved in the Research Institute of Tropical Roots and Tubers Crops (INIVIT). Differentiation of accessions was done by combining qualitative and qu…

First Evidences of Epithelial-Mesenchymal Transition and Cancer Stem-Cell Phenotype Acquisition in Dermo-Epidermal Junction of BPV-Infected Neoplasms

Dec 2017 DOI 10.14302/issn.2576-6694.jbbs-17-1869
Rita de Cassia StoccoCorresponding author

Introduction Bovine papillomavirus (BPV) is the etiological agent of bovine papillomatosis, infectious and neoplastic disease, characterized by the presence of multiple papillomas that can regress spontaneously or to persist and progress to malignancies when in association with environmental cofacto…

Acute and Chronic Wound Fluid Inversely Influence Wound Healing in an in-Vitro 3D Wound Model

Dec 2017 DOI 10.14302/issn.2640-6403.jtrr-17-1818
Manuela BesserCorresponding author University Witten/Herdecke, Centre for Biomedical Education and Research (ZBAF), Dpt. Of Translational Wound Research

If a wound progressively heals or the healing process is impaired is basically influenced by the surrounding milieu. This is reflected by the wound fluid. Its specific composition triggers the migration, proliferation and differentiation of dermal and epidermal cells which so far was not sufficientl…

Assessment of the Immune Response Induced in Neonatal Calves by Vaccination with Mycobacterium Bovis BCG Phipps Under Field Conditions

Aug 2017 DOI 10.14302/issn.2575-1212.jvhc-17-1662
Fernando Díaz OteroCorresponding author

Immunization of cattle with the bacillus Calmette-Guérin (BCG) vaccine, especially neonates, induces protection against Mycobacterium bovis (M. bovis) and has been proposed as a strategy for bovine tuberculosis (bTB) control. Therefore, the aim of this study was to evaluate the immune response induc…

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