Search results for “antiretroviral therapy”

About 16 results in articles

Open Access Pub publishes peer-reviewed, free-to-read open-access articles. Showing articles matching antiretroviral therapy — open any to read the full text, or download the PDF or XML.

HIV-Associated Peripheral Neuropathy and Antiretroviral Therapy: A Prospective Study from a Tertiary Care Centre in South India

Dec 2025 DOI 10.14302/issn.2324-7339.jcrhap-25-5515
Anagha RaoCorresponding author

Background Peripheral neuropathy (PN) is a common and debilitating complication in people living with HIV (PLHIV). While HIV itself contributes to neuropathy, certain antiretroviral therapy (ART) drugs, particularly nucleoside reverse transcriptase inhibitors (NRTIs) such as stavudine (d4T) and zido…

Human Immunodeficiency Virus Drug Resistance (HIVDR) and Baseline Characteristics among Antiretroviral Therapy (ART) experienced Children and Adolescents under the care of Chidamoyo Christian Hospital in Hurungwe, Zimbabwe

Dec 2023 DOI 10.14302/issn.2324-7339.jcrhap-23-4634
Alfred MakuraCorresponding author

Introduction Human Immunodeficiency Virus (HIV) remains a persistent global public health challenge. In 2020, approximately 37.9 million individuals were living with HIV globally, including 1.7 million children <15 years old, with a global HIV prevalence of 0.8% among adults. A larger portion of peo…

Structural Equation Modeling to Detect Predictors of CD4 Cell Count Change due to Long Term Antiretroviral Therapy Administered to HIV-Positive Adults at Felege Hiwot Teaching and Specialized Hospital, Bahir Dar, Ethiopia

Mar 2020 DOI 10.14302/issn.2641-4538.jphi-19-2610
Awoke Seyoum TegegneCorresponding author

Background The relationship between predictors and the variable of interest was estimated using a structural equation model which is used to predict latent variables. The main advantage of the SEM is the ability to estimate the direct and indirect pathways of the effect of the primary independent va…

Pattern of Use of Highly Active Antiretroviral Therapy Regimens and Pattern of Occurrence of Adverse Drug Reactions in an Indian Human Immunodeficiency Virus Positive Patients

Jun 2013 DOI 10.14302/issn.2324-7339.jcrhap-12-174
Rajesh RadhakrishnanCorresponding author Radhakrishnan Rajesh M.Pharm, Asst Professor (Senior Grade), Department of Pharmacy Practice, Manipal College of pharmaceutical Sciences, Manipal University, Manipal- 576 104, Karnataka, India.

Background: In India, Human immunodeficiency (HIV) infected patients with highly active antiretroviral therapy (HAART) are at higher risk of developing adverse drug reactions (ADRs). Objectives: The aim of this study was to characterize the pattern of use of HAART, occurrence, incidence, severity an…

When and How Should we be Measuring Adherence to Antiretroviral Therapy in Resource-Limited Settings?

Jun 2013 DOI 10.14302/issn.2324-7339.jcrhap-13-edt.1.2
Denise EvansCorresponding author

This perspective reviews practical approaches to measuring ART adherence in resource‑limited settings. It weighs self‑report, pill counts, pharmacy refill data, and biologic measures, emphasizing feasibility, bias, and programmatic integration to support sustainable HIV care.

Evaluation of Direct Cost of Adverse Drug Reactions to Highly Active Antiretroviral Therapy in Indian Human Immunodeficiency Virus Positive Patients

Dec 2012 DOI 10.14302/issn.2324-7339.jcrhap-12-71
Rajesh RadhakrishnanCorresponding author Radhakrishnan Rajesh M.Pharm, Asst Professor (Senior Grade), Department of Pharmacy Practice, Manipal College of pharmaceutical Sciences, Manipal University, Manipal- 576 104, Karnataka, India.

In India, interruptions to highly active antiretroviral therapy (HAART) are due to adverse drug reactions (ADRs) and no reports on the direct cost incurred in the management of ADRs to HAART are available. There is a need to study direct cost incurred with ADRs to HAART to explore the high economic…

Characterization of People Receiving 2-Drug Regimens (2DR) for HIV Management in Italy

Mar 2026 DOI 10.14302/issn.2994-6743.ijstd-26-6060
Pier Francesco AmadeoCorresponding author

Objective To describe the clinical features and real-world treatment of people living with human immunodeficiency virus (PLHIV) using fixed-dose or free combinations of 2-drug regimens (2DR) of antiretroviral therapy (ART). Design Italian retrospective cohort study. Methods Data were extracted from…

A Cross Sectional Analysis of Frailty and Markers of Frailty in Young People Living with HIV/AIDS

Jul 2024 DOI 10.14302/issn.2641-4538.jphi-24-5017
V K SashindranCorresponding author

Background Frailty is an ageing-associated state linked to poor prognostic outcomes. Chronic inflammation due to HIV-infection, AIDS-related infections. and the adverse effects of antiretroviral therapy (ART) all contribute to frailty in people living with HIV/AIDS (PLHA). Frailty has been comprehen…

Perspectives of Health Care Providers Working with HIV Positive Clients on Nutritional Challenges Among People Living with HIV/AIDS in Kigali, Rwanda

Mar 2020 DOI 10.14302/issn.2641-4538.jphi-20-3261
Tafadzwa DzinamariraCorresponding author

Efforts to control the Human Immunodeficiency Virus epidemic in Rwanda have seen remarkable success over the years. Effective antiretroviral therapy has played great role in improving longevity among people living with HIV/AIDS (PLWH). While this is the case, there are various nutritional challenges…

Adherence to ART among Pregnant Women Living with HIV/AIDS in Lusaka Urban

Jan 2019 DOI 10.14302/issn.2641-4538.jphi-18-1973
Victoria NthalaCorresponding author

Introduction Adherence to ART is a challenge among pregnant women living with HIV/AIDS. This has an effect on the health of the mother and the unborn child. While studies have been done, it has shown that adherence during pregnancy is a challenge Virological and clinical success depend critically on…

Disability and Health Outcomes – From a Cohort of People on Long Term ART

Aug 2017 DOI 10.14302/issn.2324-7339.jcrhap-17-1430
Hellen MyezwaCorresponding author

HIV and AIDS remains a major health problem in South Africa even after two decades since the introduction of antiretroviral therapy. Long term survival with HIV is associated with new health related issues and a risk of functional limitation/disability. The aim of this study was to assess the impact…

The Psychosocial Factors that Influencing Antiretroviral Treatment Adherence

Aug 2017 DOI 10.14302/issn.2324-7339.jcrhap-16-1316
Liranso Gebreyohannes SelamuCorresponding author

The socio-cultural context of illness has become a major research area, and it has made significant contributions to our understanding of the socio-cultural dimensions of illness. In this article, we briefly trace the roots of a socio-cultural approach to illness, and we present some of the key find…

High Rate of Asymptomatic Myocardial Ischemia in HIV Infected Population in Bobo-Dioulasso in Burkina Faso

Nov 2016 DOI 10.14302/issn.2324-7339.jcrhap-16-1271
S. J. B. TougooumaCorresponding author

Introduction The cardiovascular complications have became the 3rd cause of death and the 4th reason for hospitalization of the patients infected by the HIV. The objective of this work was to determine the frequency of asymptomatic myocardial ischemia among patients infected by the HIV receiving anti…

Physical Activity and Risk Factors Screening for Ischaemic Heart Disease in South African Individuals Living with HIV

Feb 2016 DOI 10.14302/issn.2324-7339.jcrhap-13-255
Ronel RoosCorresponding author

People living with HIV (PLWH) are at risk of developing chronic lifestyle diseases such as ischaemic heart disease (IHD). Physical inactivity is a modifiable risk factor for IHD. The level of ambulation physical activity in individuals living with HIV in a South African context is unknown. The aim o…

Cardiovascular Risk Factors Among People Being Treated for HIV in Nepal: A Cross-Sectional Study

Feb 2014 DOI 10.14302/issn.2324-7339.jcrhap-12-157
Nirmal AryalCorresponding author

Background: Human Immunodeficiency Virus (HIV) and antiretroviral therapy (ART) are found to be strongly associated with cardiovascular diseases. Data are sparse on the prevalence and distribution of cardiovascular risk factors among people being treated for HIV in South Asia region. Methods: A cros…

Prevalence and Factors Associated with Disclosure of HIV Diagnosis to Infected Children Receiving Antiretroviral Treatment in Public Health Care Facilities in Gauteng, South Africa

Jun 2013 DOI 10.14302/issn.2324-7339.jcrhap-12-74
Sphiwe MadibaCorresponding author

HIV infected children who started antiretroviral therapy (ART) in public health facilities in South Africa have survived to older age and disclosure has become an essential part of their care. Available data on HIV disclosure to children were collected much earlier in the provision of ART in South A…

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