International Physiology Journal
Open Access
The Pineal Hypothesis for Drug Dependence
Dec 2018 DOI 10.14302/issn.2578-8590.ipj-18-2524
Francesco CrespiCorresponding author
The pineal gland constitutes a major neuroendocrine organ in the brain. By mean of its neurohormone melatonin it transduces exogenous signals such as circadian and seasonal variations of light and temperature into proper hormonal changes which adjust and adapt internal endocrine functions. Alteratio…