Search results for “Tumor Suppressor Genes”

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1 article
Journal of Evolving Stem Cell Research Open Access

MicroRNA-1285 Might Potentially Regulate OCT4 Gene Expression by Direct Targeting of its Promoter

Jan 2016 DOI 10.14302/issn.2574-4372.jesr-15-768
James E. TroskoCorresponding author

The human OCT4 gene encodes a transcription factor that maintains pluripotency and self-renewal in Embryonic Stem (ES) cells. This gene generates several known transcripts by alternative promoter and alternative splicing (OCT4A, OCT4B and OCT4B1). Even though OCT4A is the main isoform responsible fo…

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