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May 2024 DOI 10.14302/issn.2470-0436.jos-23-4493
Kexin SunCorresponding author
Background Beta-Sitosterol (SIT) is an active TCM compound employed to treat diabetic retinopathy (DR). A network pharmacology approach to understanding the active ingredients and the therapeutic mechanisms underlying DR has not been pursued. Methods The potential targets for DM were identified acco…
Nov 2018 DOI 10.14302/issn.2574-4488.jna-18-2443
Wei SuCorresponding author
Renal fibrosis was a chronic and progressive process affecting kidneys in chronic kidney disease (CKD), regardless of cause. Although no effective targeted therapy yet existed to retard renal fibrosis, a number of important recent advances have highlighted the cellular and molecular mechanisms under…
Mar 2016 DOI 10.14302/issn.2470-5020.jnrt-15-800
Lili HuangCorresponding author
Although clinical trials in refractory epilepsy are currently carried out, the field of deep brain stimulation (DBS) in epilepsy is still at its initial stage. Little is known about where, when and how to stimulate and what would be the short and long consequences. Animal studies might provide clini…
Sep 2026 DOI 10.14302/issn.2641-4538.jphi-26-6405
Chuxuan ZhangCorresponding author
Despite the availability of influenza vaccines and recommendations, vaccination rates among the Chinese population have remained low and below desired public health targets. This student-led study examined how Chinese parents understand and make decisions about influenza vaccination. Using perceptio…
Aug 2026
Manjula Reddy PallerlaCorresponding author
Cyclic peptides are expected to play a significant role in the future of drug discovery and development. Their unique properties, such as enhanced target affinity, metabolic stability, and favorable pharmokinetic profiles, make them promising candidates for addressing complex therapeutic targets. In…
Aug 2026
Dale E. BredesenCorresponding author
Background/Objectives The etiology and pathophysiology of neurodegenerative diseases are incompletely understood, and the treatments largely ineffective. A unifying theory that explains otherwise poorly understood observations may help to enhance therapeutic outcomes. Methods Here is proposed a unif…
Dec 2025
Liping LiuCorresponding author
The incidence rate of melasma is notably high among patients with anxiety disorders. Aromatherapy primarily influences the physiological and psychological states of individuals through the inhalation or application of essential oils, thereby facilitating the treatment or alleviation of various condi…
Nov 2025 DOI 10.14302/issn.2326-0793.jpgr-25-5573
Oghenetega E. ImiruayeCorresponding author
Advancements in proteomic and genomic technologies have transformed molecular biology by enabling comprehensive analysis of biological systems at the molecular level. This literature review explores the evolution, methodologies, and practical applications of key proteomic and genomic techniques. In…
Nov 2025
Alexander RyanCorresponding author
Frequency neurofeedback (FNF) is a biofeedback method that targets frequencies between 1 and 50 Hz. The efficacy of FNF with autism has been labeled ‘probably efficacious’ in literature reviews in the last decade, despite new research pointing towards a higher standard. The aim of this review was to…
Nov 2025 DOI 10.14302/issn.2693-1176.ijgh-25-5745
Jolyon PooleCorresponding author
Background Healthcare worker stress, anxiety, burnout, and trauma have been widely documented across global healthcare systems. Staff in maternal and neonatal units frequently encounter emotionally distressing events and work under high pressure with limited resources. In Zambia, despite some gains…
Jan 2024 DOI 10.14302/issn.2574-4496.jtc-23-4835
Abbas Hussein Saleh HusseinCorresponding author
The prevalence of thyroid cancer is rapidly increasing worldwide, majorly due to overdiagnosis and overtreatment methods of differentiated thyroid cancer. The emergent and potent preclinical models, high-throughput molecular techniques, and genetic expression microarrays have delivered deeper insigh…
Apr 2023 DOI 10.14302/issn.2643-2811.jmbr-23-4528
Lei WangCorresponding author
Rapidly spreading Covid-19 virus and its variants, especially in metropoli- tan areas around the world, became a major health public concern. The tendency of Covid-19 pandemic and statistical modelling represent an urgent challenge in the United States for which there are few solutions. In this pape…
Dec 2022 DOI 10.14302/issn.2328-0182.japst-22-4363
Nikita S. PatilCorresponding author
The process of creating new pharmaceuticals is incredibly costly and time-consuming, and it dates back millions of years to the time when only herbal remedies were used. Furthermore, the solvation energies of the ligand and receptor site are crucial to this process because partial to complete dedica…
May 2021 DOI 10.14302/issn.2689-4602.jes-21-3837
Jeffrey O. HendersonCorresponding author
The coronavirus infectious disease (20)19 (COVID-19) pandemic is caused by a newly identified virus (2019) SARS-CoV-2, a beta coronavirus that shares similarities with other human-infecting coronaviruses. Genomic analysis suggests that SARS-CoV-2 is closely related to SARS-CoV, a bat-related coronav…
Jan 2020 DOI 10.14302/issn.2639-3166.jar-20-3165
Prem NarainCorresponding author
This commentary questions the presumption of ever‑increasing crop productivity as the singular goal. It weighs diminishing returns and ecological costs against diversification, efficiency, and demand‑side measures. The authors argue for context‑specific targets that prioritize nutrition, resilience,…
Sep 2019 DOI 10.14302/issn.2471-2140.jaa-19-2997
K.B. ShumaevCorresponding author
The paper explores the formation of a-oxoaldehydes during the interaction of glucose metabolites with hydroxyl or alkoxyl radicals. Hydroxyl radicals were generated under radiolysis of aqueous solutions, and alkoxyl radicals (t-BuO) were obtained in the model system tert-butyl hydroperoxide/Fe2+. H…
Aug 2019 DOI 10.14302/issn.2572-3030.jcgb-19-2973
Mausumi BharadwajCorresponding author
Head and Neck cancer (HNC) is one of the most prevalent and lethal cancer globally. The incidence of tobacco-induced HNC is gradually increasing in low and middle income countries. Among the various causative factors associated with HNCs, tobacco and alcohol play synergistic effect and are frequentl…
Jun 2019 DOI 10.14302/issn.2379-7835.ijn-19-2845
Jeremy J. JohnsonCorresponding author
The mangosteen fruit is a popular Southeast Asian fruit consumed for centuries. There have been a variety of xanthones isolated from the fruit, bark, roots and leaves with each having unique chemical and physical properties. Previously, the most abundant xanthone α-mangostin has been shown to inhibi…
Jun 2019 DOI 10.14302/issn.2688-5328.ijp-19-2731
Xiang WeiCorresponding author
The rise of epigenetics provides a new idea for studying the regulation of chronic pain-related genes and synaptic plasticity. External environmental stimuli can regulate BDNF genes through different epigenetic modifications. The epigenetic changes of the BDNF gene can affect the expression of its m…
Mar 2019 DOI 10.14302/issn.2379-7835.ijn-19-2578
Farid E. AhmedCorresponding author
We present below a mechanistic cellular and molecular approaches for the development of Anti-Inflammatory biomarkersof Probiotic Bacteria in Fermented Foods. Probiotics are live microorganisms that promote human health by counteracting the noxious toxic gut microflora in human intestine, by modulati…