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Apr 2023
Ricardo GobatoCorresponding author
Through T-cell engineering, researchers at the California South University (CSU) Cancer Research Institute (CRI) have shown that tumor growth can be stopped in a variety of cancers and prevented from spreading to other tissues. Findings from this study are the result of decades of research by Profes…
Jun 2020 DOI 10.14302/issn.2691-8862.jvat-20-3417
Georges TetoCorresponding author
Background Decreased antioxidant ability is one of the worsening conditions in AIDS.We aimed to evaluate total antioxidant ability among others, and their variation in HIV infected patients following their CD4+T cells count and viral load, in a context of new ART scarcity in most LMICs. Material and…
Dec 2019 DOI 10.14302/issn.2372-6601.jhor-19-3092
Anastasia S. TsingotjidouCorresponding author
Waldenström Macroglobulinemia (WM) is a B-cell lymphoproliferative disorder characterized mainly by uncontrolled accrual of M- immunoglobulin, secreted by malignant lymphoplasmatic cells. Mast cells interacting with malignant B-cells play an important role at the manifestation of the disease. Utiliz…
Aug 2018 DOI 10.14302/issn.2379-7835.ijn-18-2301
Snehasis JanaCorresponding author
Poor bone health is the primary health issue, which leads to significant health problems, stress and worsening the patients' quality of life. The potential of The Trivedi Effect®- Biofield Energy Healing on vitamin D3 as a test item (TI) and DMEM on MG-63 cells was investigated. The test items were…
Mar 2018
Loris RizzelloCorresponding author
The crusade against cancer has a new army: immunotherapy. The rational design is very simple, but brilliant at the same time. Extract the patients T-cells, reprogram them in vitro for the expression of highly specific receptors against cancer, perfuse them back to the patient. As a result, T-cells a…
Jun 2017 DOI 10.14302/issn.2690-4721.ijcm-17-1533
Soon Hoe Ho BSc (Hon)Corresponding author
This essay draws on recent evidences from SIV vaccination studies in rhesus macaques to argue for the potential importance of HIV-1-specific CD8+ T cells restricted by the non-classical major histocompatibility complex, HLA-E, in controlling HIV-1 replication. It then seeks to present a possible met…
Dec 2015 DOI 10.14302/issn.2471-2140.jaa-15-765
Zaijun ZhangCorresponding author
Reactive oxygen species (ROS) and reactive nitrogen species are believed to be one of the most important culprits in the pathogenesis of cardio/cerebrovascular diseases. Intensive researches have been conducted to target free radicals as potential treatment for cardio/cerebrovascular diseases. The 2…
Feb 2026 DOI 10.14302/issn.2372-6601.jhor-25-5944
Mikhail Y. BerezinCorresponding author
Background Oxaliplatin, a widely used chemotherapeutic agent, is associated with hematologic toxicities such as anemia, leukopenia, and thrombocytopenia. Despite their clinical relevance, the molecular mechanisms underlying lineage-specific bone marrow suppression remain poorly understood. Methods W…
Feb 2026
Hui XingCorresponding author
Keratinocytes are pivotal in mediating cutaneous inflammation. Identifying anti-inflammatory factors within these cells holds promise for developing novel therapeutic strategies to manage skin inflammation. Transcription factor EB (TFEB) has recently emerged as a key regulator linking cellular energ…
Jul 2023 DOI 10.14302/issn.2575-1212.jvhc-23-4510
Sohir YoussefCorresponding author
Dermatophytosis affect companion animal’s skin and keratin appendages as cats and dogs, resulting in red, scaly, itchy, bald, and raised patches like ring. The three main groups are Microsporum, Trichophyton and Epidermophyton. This study collected samples of skin scrapping and hairs from 130 cats a…
Nov 2022 DOI 10.14302/issn.2641-4538.jphi-22-4235
Kebe E. ObetenCorresponding author
This study investigates the effect of Aqueous extract of abelmoschus esculentus on the microanatomy of the small, large intestine and stomach and the body weight of Wister rats. Twenty-one adults male wistar rats weighing between 100-120 grams were assigned into three groups consisting of seven rats…
Mar 2022 DOI 10.14302/issn.2641-5518.jcci-22-4096
Julian Iñaki L. GarciaCorresponding author
Introduction Benign duodenocolic fistula (DCF), also known as a non-malignant fistula between the duodenum and colon, with or without cecum-involvement, is an unusual complication of different gastrointestinal (GI) diseases 12. Case This is a case of a 28-year-old Filipino female who presented with…
Feb 2022
Ricardo GobatoCorresponding author
Using samples of small cell lung tumors, a research team led by biologist Dr. Raymond discovered two new ways to induce tumor cell death. By activating ferroptosis, one of two subtypes of tumor cells can be targeted: first, iron-dependent cell death due to oxidative stress, and second, oxidative str…
Jan 2022 DOI 10.14302/issn.2372-6601.jhor-22-4061
Anna B. DanilovaCorresponding author
Background Human malignant cell models which reflect the structural and physiological complexity of tumor tissue are of great importance for preclinical research in oncology. Spheroids/tumoroids derived from solid tumors are of great interest as cellular models mimicking the first vascular-free grow…
Nov 2021 DOI 10.14302/issn.2690-4837.ijip-21-4015
Caitlin A. Connor DAOM PGDip AMP EHP-CCorresponding author
Copper (Cu) has a strong impact on the function of the immune system through several different pathways. These impacts include helping the function of monocytes, neutrophils, and macrophages, and enhancing Natural Killer cells’ activities. Cu also has a role in antimicrobial properties and inflammat…
Jul 2021 DOI 10.14302/issn.2576-6694.jbbs-21-3819
Snehasis JanaCorresponding author
The present study aimed to evaluate the effect of the Trivedi Effect®- Biofield Energy Treated/Blessed Test formulation/item (TI) composed of minerals (magnesium, zinc, copper, calcium, selenium, and iron), vitamins (ascorbic acid, pyridoxine HCl, alpha tocopherol, cyanocobalamin, and cholecalcifero…
May 2021 DOI 10.14302/issn.2689-4602.jes-21-3837
Jeffrey O. HendersonCorresponding author
The coronavirus infectious disease (20)19 (COVID-19) pandemic is caused by a newly identified virus (2019) SARS-CoV-2, a beta coronavirus that shares similarities with other human-infecting coronaviruses. Genomic analysis suggests that SARS-CoV-2 is closely related to SARS-CoV, a bat-related coronav…
Mar 2021 DOI 10.14302/issn.2575-1212.jvhc-21-3767
Faysal Abdishakur HassanCorresponding author
Antibodies and antibody fragments, especially single-domain antibodies known as nanobodies, are important tools in diagnostics, research, and therapeutics. In a conventional antibody, light and heavy chains contribute to the formation of the antigen binding site. In addition to conventional antibodi…
Feb 2021 DOI 10.14302/issn.2372-6601.jhor-21-3733
Xin QingCorresponding author
Breast implant-associated anaplastic large cell lymphoma (ALCL) is a recently recognized type of T-cell lymphoma that can develop following breast implants, with morphologic and immunophenotypic features indistinguishable from those of ALK-negative ALCL. Here we report a case of a 58-year-old woman…
May 2020 DOI 10.14302/issn.2690-6759.jpar-20-3346
Goni Abraham DogoCorresponding author
Coccidiosis in poultry is caused by protozoan parasites of the Eimeria species, which is responsible for worldwide economic losses. The aim of this study was to evaluated the therapeutic effect of NeemAzal® on Eimeria tenellain broiler Chickens as compared to Amprolium as a standard anticoccidial dr…