Search results for “Self-Renewal”

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Open Access Pub publishes peer-reviewed, free-to-read open-access articles. Showing articles matching Self-Renewal — open any to read the full text, or download the PDF or XML.

2 articles
All Journal of Skeletal Muscle 1 Journal of Evolving Stem… 1
Journal of Skeletal Muscle Open Access

The Mechanism of Decline of Senescent Skeletal Muscle Satellite Cell Self-Renewal and Regenerative Proliferation: The Role of Heparan Sulfate-FGF-2--FGFR1-p38αMAPK Axis, Sprouty1, miR-1, miR-133 and miR-29a

Apr 2020 DOI 10.14302/issn.2832-4048.jsm-20-3211
John PapaconstantinouCorresponding author

Aging mammalian skeletal muscle satellite cells (MuSCs) undergo a decline of stem cell/progenitor cell proliferative and regenerative capacity, and the development of a physiological milieu characteristic of a state of chronic sterile inflammation. p38αMAPK and ERK1/2 are two major signaling pathway…

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Journal of Evolving Stem Cell Research Open Access

MicroRNA-1285 Might Potentially Regulate OCT4 Gene Expression by Direct Targeting of its Promoter

Jan 2016 DOI 10.14302/issn.2574-4372.jesr-15-768
James E. TroskoCorresponding author

The human OCT4 gene encodes a transcription factor that maintains pluripotency and self-renewal in Embryonic Stem (ES) cells. This gene generates several known transcripts by alternative promoter and alternative splicing (OCT4A, OCT4B and OCT4B1). Even though OCT4A is the main isoform responsible fo…

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