Search results for “Resistance”

About 71 results in articles

Open Access Pub publishes peer-reviewed, free-to-read open-access articles. Showing articles matching Resistance — open any to read the full text, or download the PDF or XML.

Lineage-Specific Disruption of Hematopoiesis by Oxaliplatin: Mechanisms of Erythropoietin Resistance and Immune Suppression

Feb 2026 DOI 10.14302/issn.2372-6601.jhor-25-5944
Mikhail Y. BerezinCorresponding author

Background Oxaliplatin, a widely used chemotherapeutic agent, is associated with hematologic toxicities such as anemia, leukopenia, and thrombocytopenia. Despite their clinical relevance, the molecular mechanisms underlying lineage-specific bone marrow suppression remain poorly understood. Methods W…

Rooted Resistance: Women’s Socio-Cultural Roles in Environmental Conservation in a Patriarchal Society in Northern Uganda

Feb 2026 DOI 10.14302/issn.2693-1176.ijgh-25-5735
Christine Ruth PiloyaCorresponding author

Background In Northern Uganda’s patriarchal communities, women play vital yet underrecognized roles in environmental conservation. There is limited research examining the socio-cultural roles women play in society in northern Uganda. This study, conducted in Gulu District, examined the socio-cultura…

Malaria: A Driving Force to the Emergence and the Global Spread of Antibiotics Resistance

Mar 2025 DOI 10.14302/issn.2693-1176.ijgh-25-5429
Rasheed O. MakanjuolaCorresponding author

Malaria and bacteraemia are significant public health concerns and economic threats. In Africa, the intensity for simultaneous transmission and co-infection of Plasmodium spp and other bacteria pathogens are extremely high. It is believed that malaria suppress the immune system and enable the transl…

Fecal Shedding, Antimicrobial Resistance and In Vitro Biofilm formation on Simulated Gallstones by Salmonella Typhi Isolated from Typhoid Cases and Asymptomatic Carriers in Nairobi, Kenya

Apr 2024 DOI 10.14302/issn.2690-4721.ijcm-24-5030
John S. GunnCorresponding author

Typhoid fever, caused by the human restricted pathogen Salmonella Typhi, remains a major global public health concern. Even after successful treatment, approximately 3-5% of patients with typhoid fail to clear the bacteria within one year and become chronic carriers. Most typhoid carriers have galls…

Human Immunodeficiency Virus Drug Resistance (HIVDR) and Baseline Characteristics among Antiretroviral Therapy (ART) experienced Children and Adolescents under the care of Chidamoyo Christian Hospital in Hurungwe, Zimbabwe

Dec 2023 DOI 10.14302/issn.2324-7339.jcrhap-23-4634
Alfred MakuraCorresponding author

Introduction Human Immunodeficiency Virus (HIV) remains a persistent global public health challenge. In 2020, approximately 37.9 million individuals were living with HIV globally, including 1.7 million children <15 years old, with a global HIV prevalence of 0.8% among adults. A larger portion of peo…

Detection of carbapenem resistance mechanisms among Avian Pathogenic Escherichia coli (APEC) isolated from broiler chickens

May 2023 DOI 10.14302/issn.2575-1212.jvhc-23-4521
Aya El- shaerCorresponding author

Background The emergence and spread of carbapenem-resistant gram-negative bacteria pose a serious threat to human health. Currently, little is known about the molecular mechanisms underlying carbapenem -resistance and their prevalence among APEC in Egypt. The aim of this study was to detect APEC in…

Screening Sorghum Genotypes for Striga Resistance

Mar 2023 DOI 10.14302/issn.2639-3166.jar-22-4356
Ardaly Abdou OusseiniCorresponding author

In Niger, sorghum (Sorghum bicolor) is one of the most important staple crop for food and money. Despite the importance of the crop and its easiest adaptative capacity to dry, the crop is confronted to striga (Striga hermonthica), a plant parasite, which drastically hinder the productivity and causi…

Evaluation of Cinnamon Supplementation on Insulin Resistance, BMI and Estradiol Levels in Women with Polycystic Ovary Syndrome: A Double-Blinded Randomized Controlled Clinical Trial

Oct 2022 DOI 10.14302/issn.2381-862X.jwrh-22-4315
Anahita NazempourCorresponding author

Background Polycystic ovary syndrome (PCOS) is a serious multifactorial disorder. This study intended to assess the effect of cinnamon supplementation on estradiol level, and fasting- and two-hour (2 hpp) insulin and sugar levels in women with PCOS. Material and Methods This study was a double-blind…

Antimicrobial Resistance: A Situational Analysis in the Deido Health District, Douala, Cameroon

Jun 2021 DOI 10.14302/issn.2474-3585.jpmc-21-3851
Patrick A. NjukengCorresponding author

Background The rapid and ongoing spread of antimicrobial-resistant organisms threatens the ability to successfully prevent, control, or treat a growing number of infectious diseases in developed and developing countries. This study was designed to convey more insight on the profile of antimicrobial…

Growing Threat Increased Carbapenem-Resistance among Klebsiella pneumoniae; Antibiotic Susceptibility Pattern of Klebsiella pneumoniae in a Tertiary Care Hospital

Jan 2020 DOI 10.14302/issn.2690-4721.ijcm-19-3154
Metin DOGANCorresponding author

Background The morbidity and mortality associated with the multi drug resistant Gram negative bacterial infections pose a significant and growing challenge to clinical practitioners. Klebsiella pneumoniae, which is a substantial nosocomial pathogen and confer high levels of resistance to broad-spect…

Characterization of rpoB Gene Mutations Associated with Rifampicin Resistance in Multidrug Resistant Tuberculosis Patients Co-infected with HIV from Southern India.

Jul 2019
Shivaji K JadhavCorresponding author

Co-infection of HIV with Mycobacterium tuberculosis is a common event, particularly in developing countries. The emergence and spread of multidrug resistant tuberculosis (MDR-TB) is an increasing public problem in India. The drug-resistant M. tuberculosis strains are posing a significant challenge t…

Cellular Mechanics and Therapeutic Resistance of the Cancer Relapse

Dec 2017 DOI 10.14302/issn.2766-8630.jrnm-17-1770
Emad Y. MoawadCorresponding author

The aims of this study are to investigate the variation in the mechanical behaviour of the primary cancer from cancer relapse, and measuring the therapeutic resistance acquired by cancer relapse. A431-cultured cells were irradiated for 7 months until 85 Gy. Then, a selected single cell was left to g…

Short-Term and Chronic Effects of Aerobic and Resistance Exercise on Sleep in Young Men

Jun 2017 DOI 10.14302/issn.2474-3585.jpmc-17-1506
Clemens DrenowatzCorresponding author

Despite the generally accepted benefits of exercise on sleep there remains limited research on potential differential effects by exercise type. The purpose of the present study was to examine short-term and chronic effects of aerobic and resistance exercise on various sleep quality parameters, as we…

Rate Pressure Product Responses during an Acute Session of Isometric Resistance Training: A Randomized Trial

Feb 2017 DOI 10.14302/issn.2329-9487.jhc-17-1428
Neil A. SmartCorresponding author

Hypertension is a major modifiable risk factor for cardiovascular disease, responsible for approximately 31% of global mortality. The aim of this study was to examine the hypertensive responses and determine the peak rate pressure product, calculated by multiplying systolic blood pressure and heart…

Mechanisms Associated with Acquisition of Resistance to Butyrate-Induced Apoptosis in Colorectal Cancer Cells Using Gene Expression Analysis

Dec 2014 DOI 10.14302/issn.2326-0793.jpgr-14-598
Kim YC FungCorresponding author

Colorectal cancer is one of the most commonly diagnosed cancers worldwide and its prevalence can be reduced by changes to lifestyle and diet. Fermentation of dietary fibre by the gut microbiota and formation of short chain fatty acids, in particular butyrate, is widely thought to play a role in prev…

Carbapenem-resistant Enterobacterales at a quaternary public hospital in Durban, KwaZulu-Natal: Ascertaining the clinical and molecular paradigm shift following COVID-19

Oct 2026 DOI 10.14302/issn.2690-4721.ijcm-26-6425
Nitesh BrijlalCorresponding author

Background Extensive carbapenem use has resulted in an increasing occurrence of difficult-to-treat resistant gram-negative bacteria (DTR-GNB), such as carbapenem-resistant Enterobacterales (CREs). The international antimicrobial resistance (AMR) landscape was profoundly impacted due to varying antib…

Use of Stem Cell Growth and Differentiation Factors (Scdsf) in Central Vertigo

Oct 2026 DOI 10.14302/issn.2379-8572.joa-26-6454
Giorgia GrappeggiaCorresponding author

The clinical use of SCDSF factors in neuro-degenerative pathologies offers a potential therapeutic opportunity. Our observational study aims to evaluate its efficacy in patients affected by Central Vertigo1. A case series divided into two subgroups, all affected by non-migrainous central vertigo, wa…

Reduced Tissue Oxygenation and Altered Valsalva Hemodynamics in Young Adults with Type 1 Diabetes

May 2026 DOI 10.14302/issn.2578-8590.ipj-26-6121
Maria Bitsch PoulsenCorresponding author

Aims Cardiac autonomic neuropathy is currently an untreatable progressive complication of type 1 diabetes (T1D). Impaired microcirculation is a suspected cause of nerve degeneration in TID. We investigated whether cardiovascular autonomic reflexes often used as indices of nerve functions, are associ…

Honour and Shame as Moral-Emotional Identity Regulation in Diaspora: An Interpretative Phenomenological Analysis of Young British South Asian Women

Apr 2026 DOI 10.14302/issn.2644-1101.jhp-26-6100
Aman Asif-MalikCorresponding author

Honour and shame are central moral constructs within many South Asian communities, yet their psychological internalisation in diasporic contexts remains underexamined. This qualitative study explored how young British South Asian women (aged 18–25; N = 6) understand and negotiate honour in relation…

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