Search results for “Pharmacokinetics”

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Open Access Pub publishes peer-reviewed, free-to-read open-access articles. Showing articles matching Pharmacokinetics — open any to read the full text, or download the PDF or XML.

Dolutegravir: Pharmacokinetics and Pregnancy Profile

Mar 2022
Gudisa BeredaCorresponding author

Dolutegravir suppresses this integration enzyme, so human immune virus can’t create every greater copies of itself, thus ‘’integrase inhibitor.’’ Dolutegravir is hastily absorbed pursuing oral administration. The median maximum plasma concentration is reached 1.5–2.5 hours after oral uptake with a m…

Sulfonamides: Historical Discovery Development (Structure-Activity Relationship Notes)

May 2018
Farah YousefCorresponding author

Sulfonamide group is a magic group introduced as the main core for different bio-activities in drug industry. According to its substitutes, literature divides sulfonamide derivatives to antibacterial sulfonamides and non-anti-bacterial sulfonamides. As Data was collected from different sources such…

Single Nucleotide Polymorphism Profiles of Patients with Acute Renal Rejection to Personalize Immunosuppressive Therapy: Preliminary Results from An On-Going, Italian Study

Jun 2017 DOI 10.14302/issn.2576-9359.jot-17-1603
Carlotta CapraraCorresponding author

Single-nucleotide polymorphisms (SNPs) in genes involved in immune responses and in the pharmacokinetics/pharmacodynamics of immunosuppressive drugs influence transplant outcomes of patients receiving the same immunosuppressive therapy. The aim of our preliminary study was to determine the SNPs prof…

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