Journal of Colon and Rectal Cancer
Open Access
Overexpression of Prostate Apoptosis Response Protein-4 In Colon Cancer Cells Can Inhibit Metastasis by Upregulating E-cadherin Expression
May 2015 DOI 10.14302/issn.2471-7061.jcrc-14-574
Rosalyn B. IrbyCorresponding author
Colon cancer has a five-year survival of 64.7%, and about 50,000 people are expected to die from colon cancer this year. Patients with metastatic colorectal cancer have a significantly worse prognosis, a 12.9% five-year survival. This emphasizes the need for strategies to inhibit the growth and meta…