Search results for “Metastasis”

About 22 results in articles

Open Access Pub publishes peer-reviewed, free-to-read open-access articles. Showing articles matching Metastasis — open any to read the full text, or download the PDF or XML.

Isolation of Burkholderia cepacia Complex from Pericardial Fluid in a Patient with Lung Adenocarcinoma with Metastasis: A Rare Case Report

Jul 2026 DOI 10.14302/issn.2690-4721.ijcm-26-6132
K MirlekarCorresponding author

Burkholderia cepacia complex was isolated from pericardial fluid in a patient with metastatic lung adenocarcinoma, representing a rare opportunistic pericardial infection. Clinical improvement following targeted antimicrobial therapy supported its pathogenic significance and highlights the importanc…

Analysis of Clinical Prognostic Variables for Triple Negative Breast Cancer Histological Grading and Lymph Node Metastasis

Dec 2018 DOI 10.14302/issn.2641-5526.jmid-18-2488
Juan Luis Fernández-MartínezCorresponding author

Background: Triple Negative Breast Cancer (TNBC) is a type of breast cancer with very bad prognosis. Predicting the histological grade (HG) and the lymph nodes metastasis is crucial for developing more suitable treatment strategies. Methods: We present the main clinical and pathological variables to…

Journal of Neoplasms Open Access

Breast Cancer, Chemokines, And Metastasis: A Search for Decoy Ligands of the CXCR4 Receptor

Aug 2018 DOI 10.14302/issn.2639-1716.jn-18-2208
Gerald J. MizejewskiCorresponding author

Breast cancer (BC) is the leading cause of cancer-related deaths in young to middle-aged women worldwide. Moreover, the survival rate in BC-patients is only 20% when associated with metastatic disease. The high mortality rate observed in BC women with metastatic disease has precipitated a major chal…

Newly-Detected Solitary Bony Lytic/Sclerotic Lesion with Soft Tissue Mass in a Previously Treated Case of High-Risk Medulloblastoma: Importance of Contemporary Pathology Techniques to Differentiate Second Malignant Neoplasm from Extra-Neuraxial Metastasis 

Jun 2015 DOI 10.14302/issn.2576-182X.jbsc-14-576
Tejpal GuptaCorresponding author

Multi-modality therapy has led to significant improvement in outcomes for childhood medulloblastoma; however, long-term survivors have become more susceptible to late effects of therapy including induction of second malignant neoplasms and even remain at an increased risk of late relapses including…

Overexpression of Prostate Apoptosis Response Protein-4 In Colon Cancer Cells Can Inhibit Metastasis by Upregulating E-cadherin Expression

May 2015 DOI 10.14302/issn.2471-7061.jcrc-14-574
Rosalyn B. IrbyCorresponding author

Colon cancer has a five-year survival of 64.7%, and about 50,000 people are expected to die from colon cancer this year. Patients with metastatic colorectal cancer have a significantly worse prognosis, a 12.9% five-year survival. This emphasizes the need for strategies to inhibit the growth and meta…

Outcomes of Differentiated Thyroid Cancer Patients Treated with Surgery and Radioactive Iodine at SQCCCRC

Jun 2026 DOI 10.14302/issn.2574-4496.jtc-26-6304
Omayma ElshafieCorresponding author

Objective To evaluate the treatment outcomes of patients with Differentiated thyroid cancer (DTC) who underwent total thyroidectomy followed by RAI therapy at the Sultan Qaboos Comprehensive Cancer Care and Research Centre (SQCCCRC) in Oman. Methods This is a retrospective observational clinical stu…

Evolution of the Solid Human Tumor Cells Properties in Various Experimental Systems in Vitro

Jan 2022 DOI 10.14302/issn.2372-6601.jhor-22-4061
Anna B. DanilovaCorresponding author

Background Human malignant cell models which reflect the structural and physiological complexity of tumor tissue are of great importance for preclinical research in oncology. Spheroids/tumoroids derived from solid tumors are of great interest as cellular models mimicking the first vascular-free grow…

The Vascular Swirls- Angiomatoid Fibrous Histiocytoma

Jan 2021 DOI 10.14302/issn.2689-5773.jcdp-20-3648
Anubha BajajCorresponding author

Angiomatoid fibrous histiocytoma (AFH)  is an exceptional, soft tissue neoplasm of indeterminate lineage and intermediate malignancy associated with minimal localized tumour reoccurrence and infrequent distant metastasis. Preliminarily contemplated to be a variant or  derivative of malignant fibrous…

Comparative Survival Assessment of Two-Dimension (2D) vs Three-Dimension (3D) Brachytherapy Treatment in Cervical Cancer: A Retrospective Case Control Study

Nov 2020 DOI 10.14302/issn.2766-8630.jrnm-20-3594
Pitchaya SakyanunCorresponding author

Purpose The purpose of this study was to assess the efficacy (overall survival, local control, progression free survival (PFS) and toxicities between two dimension (2D) and three dimension (3D) CT guided brachytherapy without using interstitial needles in cervical cancer patients. Material and Metho…

The Minimalistic Malignancy- Low grade Fibromyxoid Sarcoma

Nov 2020 DOI 10.14302/issn.2689-5773.jcdp-20-3577
Anubha BajajCorresponding author

Low grade fibromyxoid sarcoma (LGFMS) is an exceptional, low grade, soft tissue sarcoma  with indolent biological behaviour, extensive preclinical stage, enhanced localized tumour reoccurrence and delayed, distant metastasis. As the deceptively benign neoplasm was initially scripted by Evans in 1987…

Investigation of Neoplastic Cells in the Bone Marrow of Female Dogs with Mammary Gland Tumors

Jul 2020 DOI 10.14302/issn.2575-1212.jvhc-20-3434
Pamela R.R. MoreiraCorresponding author

Background The mammary glands are the second most common tumor development site in female dogs. One of the ways of staging such tumors is to evaluate the presence or absence of distant metastasis, including in bone marrow. Such findings in human medicine are associated with poor survival of women wi…

Lung Cancer and Isolated Adrenal Metastases: Different Disease?

Mar 2019 DOI 10.14302/issn.2642-9241.jrd-18-2499
Rodrigo A. S. SardenbergCorresponding author

Distant metastases generally indicate disseminated disease and the standard treatment for these patients is palliative chemotherapy. Retrospective series showed that selected patients with metastatic lung cancer and a solitary extrathoracic disease could be effectively treated with curative intentio…

Quantification of Micrornas by Absolute Dpcr for the Diagnostic Screening of Colon Cancer

Feb 2019 DOI 10.14302/issn.2471-7061.jcrc-18-2526
Farid E. AhmedCorresponding author

There is currently no validated micro(mi)RNA diagnostic stool test to screen for colon cancer (CC) on the market because of the complexity of fecal density, vulnerability of stool to daily changes, and the presence of three sources of miRNAs in stool (cell-free from fecal homogenates, exsosomal miRN…

Perioperative Period is a Critical Gap for Minimal Residual Cancer Cells Progression and Therapy: Biological and Molecular Based Evidences

Oct 2018 DOI 10.14302/issn.2372-6601.jhor-18-2396
Anwar Tawfik AminCorresponding author

Although surgery is the main treatment for solid tumors, it could enhance the growth and metastasis of minimal residual cancer. In this review article we have discussed the perioperative changes in cancer cells and surrounding environment as well as the alterations in the immune system. Several tria…

First Evidences of Epithelial-Mesenchymal Transition and Cancer Stem-Cell Phenotype Acquisition in Dermo-Epidermal Junction of BPV-Infected Neoplasms

Dec 2017 DOI 10.14302/issn.2576-6694.jbbs-17-1869
Rita de Cassia StoccoCorresponding author

Introduction Bovine papillomavirus (BPV) is the etiological agent of bovine papillomatosis, infectious and neoplastic disease, characterized by the presence of multiple papillomas that can regress spontaneously or to persist and progress to malignancies when in association with environmental cofacto…

Study of VCAM-1 Gene Expression in Normal and Tumoral Tissues in Patients with Colorectal Cancer

Nov 2017 DOI 10.14302/issn.2576-6694.jbbs-17-1744
Frouzandeh MahjoubiCorresponding author

Aim: Colorectal cancer is one of the most commonly diagnosed cancers in the world. Cell adhesion molecules play an important role in the progression of various cancers. It has been shown that the high level expression of some Cell adhesion molecule could be a new diagnostic factor for several cancer…

Journal of Neoplasms Open Access

The Role of Heparin in Lung Cancer

Jul 2017 DOI 10.14302/issn.2639-1716.jn-17-1499
Walid Abu ArabCorresponding author

Non-small cell lung cancer is a major health problem worldwide. Surgery is still the mainstay of treatment especially in early stages of the disease. Despite the fact that surgery is the potentially curative treatment, the recurrence and mortality rates are still high specifically with more advanced…

Psychopathology of Brain Frontal Lobe Tumors : When the Neurosurgery Meets Psychiatry

May 2017 DOI 10.14302/issn.2694-1201.jsn-17-1470
Domenico ChirchigliaCorresponding author Professor of Department of Neurosurgery, University of Catanzaro

Brain tumors occur when abnormal cells form within the brain.There are two main types of tumors: malignant and benign tumors. Then, tumors can be divided into primary that start within the brain, and secondary tumors that have spread from somewhere else, known as brain metastasis tumors. Secondary b…

Importance of Neutrophil/Lymphocyte Ratio in Squamous-Cell Carcinoma of the Larynx

Jan 2017 DOI 10.14302/issn.2379-8572.joa-16-1399
Muhammet fatih topuzCorresponding author

Aim: The relation between inflammation and cancer has been known since the 19th century. However, investigations on the pathogenesis and pathophysiology of this relation have begun recently. It was demonstrated that increased neutrophil/lymphocyte ratio is a poor prognostic factor in some malignanci…

Primary Malignant Melanoma Of The Parotid Gland Combined 18F-FDGPET/CT And Immunochemical Diagnosis with Literature Review

Nov 2016 DOI 10.14302/issn.2574-4526.jddd-16-1322
Mohammed DarouichiCorresponding author Institute medical radiology

Summary Primary malignant melanoma arising from the parotid gland is extremely rare and only sporadic cases have been described. This entity is characterized by delayed diagnosis, poor prognosis and controversial pathogenesis. We report a case of primary malignant melanoma of the parotid gland in a…

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