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Jun 2026 DOI 10.14302/issn.2690-4721.ijcm-26-6039
Nidhi RaoCorresponding author
Background Mucormycosis is a rapidly progressive invasive fungal infection associated with high mortality in patients with hematological malignancies such as Acute Lymphoblastic Leukemia(ALL). Early diagnosis is challenging because clinical and radiological findings are often nonspecific, and tissue…
Mar 2023 DOI 10.14302/issn.2641-5518.jcci-23-4506
Anu PartanenCorresponding author
Limited data exist on the mechanisms promoting clonal expression of BCR-ABL1 cells in various myeloproliferative disorders. We present a patient whose Janus Kinase (JAK) 2 V617F-negative idiopathic myelofibrosis (IMF) transformed to Philadelphia-positive chronic myeloid leukemia (CML). A 55-year-old…
May 2015 DOI 10.14302/issn.2471-2175.jdrt-14-618
Susan Y ChonCorresponding author
A case of a solitary necrotic cutaneous lesion in a neutropenic patient with acute myeloid leukemia is described. The report discusses infectious and non‑infectious differentials, work‑up under immunosuppression, and targeted management.
Feb 2014 DOI 10.14302/issn.2372-6601.jhor-13-358
Swarna MandavaCorresponding author
Acute lymphoblastic leukemia (ALL) is a rapid form of leukemia characterized by clonal proliferation and accumulation of immature hematopoietic stem cells of the lymphoid lineage in the bone marrow as well as peripheral blood. Chromosomal aberrations identified in childhood ALL have an important rol…
Aug 2026 DOI 10.14302/issn.2377-2549.jndc-26-6392
Grigorii G. SivetsCorresponding author
Chemoenzymatic synthesis of a series of purine modified 3′ deoxyribonucleosides was studied from purine derivatives as acceptors and an excess of 3′-deoxyuridine as the donor, prepared by the chemical deamination of 3′-deoxycytidine, using recombinant uridine and purine nucleoside phosphorylases as…
Apr 2022 DOI 10.14302/issn.2372-6601.jhor-22-4133
Xin QingCorresponding author
Background Monoclonal gammopathy of undetermined significance (MGUS) and chronic myeloid leukemia (CML) are diseases of different lineages. The diagnosis of both MGUS and CML in the same patient is a rare occurrence and has not been reported in much literature. Case Presentation We describe a 56-yea…
Dec 2018 DOI 10.14302/issn.2381-862X.jwrh-18-2459
Snehasis JanaCorresponding author
The objective of the study was to investigate the effect of Consciousness Energy Healing based DMEM medium on the level of alkaline phosphatase enzyme (ALP) activity in Ishikawa cells. The test item, DMEM medium was divided into two parts. One part of the test item received Consciousness Energy Heal…
Feb 2018 DOI 10.14302/issn.2372-6601.jhor-18-1938
Elsayed Mostafa AliCorresponding author
Neuropilins are transmembrane glycoproteins that act as receptors for vascular endothelial growth factors (VEGF) and are involved in the process of tumor angiogenesis. Its importance in hematological malignancies such as acute leukemia (AL) remains to be elucidated. The aim of this study was to eval…
Nov 2017 DOI 10.14302/issn.2372-6601.jhor-17-1761
Gitte Lee MortensenCorresponding author
With the introduction of tyrosine kinase inhibitors (TKI), patients with chronic myeloid leukemia (CML) have obtained survival rates close to normal. It may appear paradoxical, then, that medication adherence is suboptimal in some health care settings. As the first of its kind, this study aimed to e…
Dec 2016 DOI 10.14302/issn.2372-6601.jhor-16-1330
Isacco FerrariniCorresponding author
Immune thrombocytopenia (ITP) is a rare but well-recognized post-allogeneic hematopoietic stem cell transplant (HSCT) autoimmune complication for which a standard treatment approach is lacking. Herein we report on an adult patient affected by high-risk acute myeloid leukemia (AML) who developed a po…
Feb 2016 DOI 10.14302/issn.2372-6601.jhor-15-822
I.V. ChernikovCorresponding author
Institute of Chemical Biology and Fundamental Medicine SB RAS.
Small interfering RNA (siRNA) based drugs for overcoming multiple drug resistance of hematological malignancies could solve the problem of poor response to the chemotherapy and hight relapse rate. The main factor that significantly limits biomedical application of siRNA is inefficient delivery to ta…