Open Access Pub publishes peer-reviewed, free-to-read open-access articles. Showing
articles matching Immune System — open any to read the full text,
or download the PDF or XML.
Jun 2017 DOI 10.14302/issn.2474-7785.jarh-17-1578
Daisy WilsonCorresponding author
Frailty describes a medical syndrome that confers increased vulnerability to disproportionate changes in health status following minor stressors. With loss of homeostatic reserve in multiple physiological systems, frailty conveys an increased risk of adverse health outcomes. Despite the lack of a cl…
Sep 2026
Yilkal Tariku BelayCorresponding author
Immunoglobulins, commonly known as antibodies, are glycoprotein molecules present on B lymphocytes and within the bloodstream. They are essential components of the immune response, as they detect the harmful molecules of test compounds and stimulate the immune system to manifest proportional counter…
Mar 2025 DOI 10.14302/issn.2693-1176.ijgh-25-5429
Rasheed O. MakanjuolaCorresponding author
Malaria and bacteraemia are significant public health concerns and economic threats. In Africa, the intensity for simultaneous transmission and co-infection of Plasmodium spp and other bacteria pathogens are extremely high. It is believed that malaria suppress the immune system and enable the transl…
Jun 2024 DOI 10.14302/issn.2374-9431.jbd-24-5077
Raúl IseaCorresponding author
Dengue is a global arbovirus disease primarily carried by Aedes aegypti and Aedes albopictus mosquitoes. It has four serotypes (DENV1, DENV2, DENV3, and DENV4) and is classified into distinct genotypes. The epidemic is complicated by immunological interactions and viral lineage turnover. Neurologica…
Jan 2024
Selene MangaCorresponding author
Drug-resistant tuberculosis (DR-TB) is the most urgent public health problem to solve in Peru, according to the Ministry of Health 1. In the WHO Global TB Report 2021, Peru has the highest burden of DR-TB in the Americas (Table 1), with 38% of TB cases either RR or MDR. In addition, the Ministry rep…
Jun 2022 DOI 10.14302/issn.2328-0182.japst-22-4193
Yilkal Tariku BelayCorresponding author
The strategy for safe drug discovery and development has limited clinical success as compared to wasted time and resources annually. This is due to the fact that the results of multiphase preclinical trials are less likely to make an accurate early prediction on the safety of test compounds to progr…
Jan 2022 DOI 10.14302/issn.2372-6601.jhor-22-4061
Anna B. DanilovaCorresponding author
Background Human malignant cell models which reflect the structural and physiological complexity of tumor tissue are of great importance for preclinical research in oncology. Spheroids/tumoroids derived from solid tumors are of great interest as cellular models mimicking the first vascular-free grow…
Nov 2021 DOI 10.14302/issn.2690-4837.ijip-21-4015
Caitlin A. Connor DAOM PGDip AMP EHP-CCorresponding author
Copper (Cu) has a strong impact on the function of the immune system through several different pathways. These impacts include helping the function of monocytes, neutrophils, and macrophages, and enhancing Natural Killer cells’ activities. Cu also has a role in antimicrobial properties and inflammat…
Mar 2021 DOI 10.14302/issn.2575-1212.jvhc-21-3767
Faysal Abdishakur HassanCorresponding author
Antibodies and antibody fragments, especially single-domain antibodies known as nanobodies, are important tools in diagnostics, research, and therapeutics. In a conventional antibody, light and heavy chains contribute to the formation of the antigen binding site. In addition to conventional antibodi…
Sep 2020 DOI 10.14302/issn.2694-2283.jsem-20-3539
Awoke TibebuCorresponding author
The following document provides important information that everybody know about physical exercise as a means of managing COVID-19. It addresses the health benefits of physical exercise on our body’s immune system, and stress reduction. Already today in the entire world, coronavirus is now the leadin…
Aug 2020 DOI 10.14302/issn.2691-8862.jvat-20-3513
Jainish PatelCorresponding author
This paper explores the trends, issues and challenges confronting the successful vaccine development for the novel Coronavirus disease (COVID-19). Right from the commencement of the COVID-19 pandemic, no drugs or vaccine has been developed nor approved for treating those down with COVID-19. This yea…
Jun 2020 DOI 10.14302/issn.2372-6601.jhor-20-3372
Fatih OzcelikCorresponding author
Immune thrombocytopenia currently called under its’ new name, immune thrombocytopenic purpura (ITP) is a disease characterized by thrombocytopenia, in which the body attacks its own platelets due to the disorders in immune system. The pathophysiology of this disease includes increased platelet destr…
May 2020 DOI 10.14302/issn.2641-7669.ject-20-3313
A.J ThatheyusCorresponding author
PG & Research Department of Zoology, The American College, Madurai, Tamil Nadu, India.
Industrial effluents containing heavy metals may reach aquatic systems either through direct discharge or surface runoff and cause damage to aquatic organisms affecting their immune system and health. Hence the present study has been undertaken to observe the effects of hexavalent chromium on the WB…
May 2020 DOI 10.14302/issn.2692-1537.ijcv-20-3345
Fatih OzcelikCorresponding author
While the COVID-19 pandemic has raised concerns about the future of people worldwide, it has made it necessary to take measures with high economic costs, including quarantine. We consider it is more logical for some scientists to investigate time-saving treatment options until vaccination studies, w…
Jun 2019 DOI 10.14302/issn.2690-0904.ijoe-19-2792
Manfred NeubergerCorresponding author
In deaths and diseases attributed to tobacco smoke cardiovascular events exceed cancer and respiratory diseases. Second hand smoke promotes the development of arteriosclerosis and can trigger acute changes of endothelial function and blood coagulability. Indoor smoking bans reduced coronary syndrome…
May 2019 DOI 10.14302/issn.2324-7339.jcrhap-19-2746
Sabina KhanamCorresponding author
Human immunodeficiency viruses causes HIV infection in humans belongs to two species of Lentivirus. It damages the cells of immune system which leads to weak immune system and the ability to fight from infections and diseases. This study was conducted to investigate the prevalence rate of HIV infect…
Mar 2019 DOI 10.14302/issn.2641-5518.jcci-19-2664
Ghada ElGoharyCorresponding author
Lenalidomide is a second generation immunomodulatory agent and a potent analogue of thalidomide that is FDA approved mainly for the treatment of multiple myeloma (MM) and transfusion-dependent anemia due to low or intermediate-1- risk myelodysplastic syndromes (MDS) associated with 5q deletion among…
Jan 2019 DOI 10.14302/issn.2572-3030.jcgb-18-2527
Xi ZhangCorresponding author
As remarkable advances have been made in immunotherapies, the overall goal of immunotherapy has become the selection of patients and evaluating the benefits of treatment. One of the major obstacles to develop immunotherapies is the lack of effective immune monitoring. Monitoring of key changes in th…
Dec 2018 DOI 10.14302/issn.2576-6694.jbbs-18-2489
Monica ButnariuCorresponding author
Essential oils, called volatile oils or ethereal oils, are natural metabolic secretions of plants, the role of which is not yet fully understood by science. Some specialists consider them to be true plant hormones, fluid manifestations of the immune system of plants, in the sense that they contribut…
Oct 2018 DOI 10.14302/issn.2372-6601.jhor-18-2396
Anwar Tawfik AminCorresponding author
Although surgery is the main treatment for solid tumors, it could enhance the growth and metastasis of minimal residual cancer. In this review article we have discussed the perioperative changes in cancer cells and surrounding environment as well as the alterations in the immune system. Several tria…