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Sep 2026
Yilkal Tariku BelayCorresponding author
Immunoglobulins, commonly known as antibodies, are glycoprotein molecules present on B lymphocytes and within the bloodstream. They are essential components of the immune response, as they detect the harmful molecules of test compounds and stimulate the immune system to manifest proportional counter…
Feb 2026 DOI 10.14302/issn.2372-6601.jhor-25-5944
Mikhail Y. BerezinCorresponding author
Background Oxaliplatin, a widely used chemotherapeutic agent, is associated with hematologic toxicities such as anemia, leukopenia, and thrombocytopenia. Despite their clinical relevance, the molecular mechanisms underlying lineage-specific bone marrow suppression remain poorly understood. Methods W…
Feb 2024 DOI 10.14302/issn.2379-7835.ijn-24-4938
Mina SuhCorresponding author
Public health interest in vaccinations and immune protection has increased with the COVID-19 pandemic. Dairy products are an important source of protein and other nutrients, and there are unresolved research questions regarding the potential health impact of dairy products on the enhancement of immu…
Jan 2024 DOI 10.14302/issn.2328-0182.japst-23-4771
Yilkal Tariku BelayCorresponding author
Background Immunoglobulins are bio-receptors found embedded in the cell membrane with a biological role that detects the harmful molecules of a test compound. These bio-receptors interface between a biological system and its external environment that transduce information to the effector via interme…
Mar 2023 DOI 10.14302/issn.2474-7785.jarh-22-4381
Yilkal Tariku BelayCorresponding author
Background Ageing is a life process in which progressive molecular, cellular, physiological and anatomical changes manifesting in humans and animals including other organisms lead to the decline of biological functions. Immunoglobulins (Igs) are glycoprotein molecules produced by white blood cells m…
Jul 2020 DOI 10.14302/issn.2692-1537.ijcv-20-3459
Fatih OzcelikCorresponding author
As there is no specific treatment yet, the fight against the COVID-19 pandemic is being carried out with great difficulty today. The use of immune plasma is seen as a promising option since there is expectation that it will reduce mortality, as in influenza pandemics experienced in 1918 and 2009. Ho…
Jun 2020 DOI 10.14302/issn.2641-5518.jcci-20-3370
Marcus Vinícius Magno GonçalvesCorresponding author
Autoimmune polyglandular syndromes (APS) are a diverse group of clinical conditions characterized by loss of immune tolerance in various tissues. This condition can be diagnosed in childhood or adulthood, with changes in the components of the disease throughout life. Here, an unusual case of associa…
Jun 2020 DOI 10.14302/issn.2372-6601.jhor-20-3372
Fatih OzcelikCorresponding author
Immune thrombocytopenia currently called under its’ new name, immune thrombocytopenic purpura (ITP) is a disease characterized by thrombocytopenia, in which the body attacks its own platelets due to the disorders in immune system. The pathophysiology of this disease includes increased platelet destr…
May 2020 DOI 10.14302/issn.2692-1537.ijcv-20-3345
Fatih OzcelikCorresponding author
While the COVID-19 pandemic has raised concerns about the future of people worldwide, it has made it necessary to take measures with high economic costs, including quarantine. We consider it is more logical for some scientists to investigate time-saving treatment options until vaccination studies, w…
Mar 2019 DOI 10.14302/issn.2379-7835.ijn-19-2639
Olivia McCarthyCorresponding author
Nine healthy individuals with a mean ± SD BMI of 22.0 ± 0.7 kg/m² and age of 20 ± 0.2 years, participated in this single-blind randomised, crossover trial investigating the impact of ingesting two different honeys (1) Tropical Forest Honey (TFH) and (2) Manuka Honey; strength 12+ (MAN) on circulatin…
Sep 2018
Ghazi ChabchoubCorresponding author
A concise review of autoimmune disease etiology emphasizes genetic susceptibility, inflammatory pathways, and environmental exposures. It points to systems approaches for risk stratification and prevention with illustrative examples.
Aug 2017 DOI 10.14302/issn.2575-1212.jvhc-17-1662
Fernando Díaz OteroCorresponding author
Immunization of cattle with the bacillus Calmette-Guérin (BCG) vaccine, especially neonates, induces protection against Mycobacterium bovis (M. bovis) and has been proposed as a strategy for bovine tuberculosis (bTB) control. Therefore, the aim of this study was to evaluate the immune response induc…
Jun 2017 DOI 10.14302/issn.2690-4721.ijcm-17-1533
Soon Hoe Ho BSc (Hon)Corresponding author
This essay draws on recent evidences from SIV vaccination studies in rhesus macaques to argue for the potential importance of HIV-1-specific CD8+ T cells restricted by the non-classical major histocompatibility complex, HLA-E, in controlling HIV-1 replication. It then seeks to present a possible met…
Jun 2017 DOI 10.14302/issn.2474-7785.jarh-17-1578
Daisy WilsonCorresponding author
Frailty describes a medical syndrome that confers increased vulnerability to disproportionate changes in health status following minor stressors. With loss of homeostatic reserve in multiple physiological systems, frailty conveys an increased risk of adverse health outcomes. Despite the lack of a cl…
Dec 2016 DOI 10.14302/issn.2372-6601.jhor-16-1330
Isacco FerrariniCorresponding author
Immune thrombocytopenia (ITP) is a rare but well-recognized post-allogeneic hematopoietic stem cell transplant (HSCT) autoimmune complication for which a standard treatment approach is lacking. Herein we report on an adult patient affected by high-risk acute myeloid leukemia (AML) who developed a po…
Jul 2026 DOI 10.14302/issn.2470-0436.jos-26-6357
Muhammad AwanCorresponding author
Herpes zoster ophthalmicus (HZO) is a manifestation of varicella-zoster virus (VZV) reactivation involving the ophthalmic division of the trigeminal nerve, carrying significant risk of vision-threatening complications. Diplopia in HZO is often attributed to cranial nerve palsy, although orbital myos…
Apr 2026 DOI 10.14302/issn.2640-6403.jtrr-26-6077
Margaret KalmetaCorresponding author
Delayed wound healing in diabetes is characterized by impaired angiogenesis, persistent inflammation, extracellular matrix dysregulation, and peripheral neuropathy. A preclinical study was conducted using a diabetic mouse delayed wound model to evaluate the surrounding tissue of a wound, (its periwo…
Jan 2026 DOI 10.14302/issn.2470-0436.jos-25-5905
Mohammed Al-YarabiCorresponding author
Purpose To report a rare case of Mooren’s ulcer in a healthy young male without systemic autoimmune disease, and to highlight the effectiveness of conjunctival resection as therapy for cases unresponsive to medical management. Case report A 34-year-old immunocompetent male presented with progressive…
Nov 2025 DOI 10.14302/issn.2326-0793.jpgr-25-5573
Oghenetega E. ImiruayeCorresponding author
Advancements in proteomic and genomic technologies have transformed molecular biology by enabling comprehensive analysis of biological systems at the molecular level. This literature review explores the evolution, methodologies, and practical applications of key proteomic and genomic techniques. In…
Mar 2025 DOI 10.14302/issn.2693-1176.ijgh-25-5429
Rasheed O. MakanjuolaCorresponding author
Malaria and bacteraemia are significant public health concerns and economic threats. In Africa, the intensity for simultaneous transmission and co-infection of Plasmodium spp and other bacteria pathogens are extremely high. It is believed that malaria suppress the immune system and enable the transl…