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Dec 2025 DOI 10.14302/issn.2997-2108.jcc-25-5657
Zahraa M EssamCorresponding author
Viral infections contribute to a significant proportion of human cancers, with human papillomavirus (HPV) being one of the most well-established oncogenic viruses. This review summarizes HPV biology, transmission, classification, molecular mechanisms of carcinogenesis, epidemiology of HPV-associated…
Dec 2025 DOI 10.14302/issn.2997-2108.jcc-25-5518
Steven KikonyogoCorresponding author
Cervical cancer is the fourth most common cancer in women globally, with 660,000 new cases and 350,000 deaths in 2022. The burden is disproportionately high in low- and middle-income countries (LMICs), particularly sub-Saharan Africa. Despite proven interventions like HPV vaccination and screening,…
Apr 2024 DOI 10.14302/issn.2994-6743.ijstd-24-5006
Nargis Khatoon Hossein Mehdi PoorCorresponding author
Objectives This study explores the clinical characteristics, associated infections, and management outcomes of syphilis within a specific population over the years 2018 to 2022. With a focus on the frequency, clinical manifestations, and co-infections of syphilis, the research addresses a critical g…
Mar 2024 DOI 10.14302/issn.2997-2108.jcc-23-4838
Konul S. MardanovaCorresponding author
Among the reproductive cancers cervical cancer has special place, because the second most frequent cause of cancer-related death among women worldwide. The studies suggested that the PI3K/mTOR/AKT signaling pathway is associated with certain reproductive tumors. A lot of research is ongoing for unde…
Mar 2024 DOI 10.14302/issn.2997-2108.jcc-20-3675
Zheng YuanCorresponding author
Pemphigus vulgaris is an autoimmune-mediated blistering disease. Cervical involvement is rare. A 38 year old nulliparous woman with PV on oral prednisolone and azathioprine was referred to the Gynaecology service for an abnormal cervical cytological smear showing low-grade squamous intraepithelial l…
Aug 2019 DOI 10.14302/issn.2572-3030.jcgb-19-2973
Mausumi BharadwajCorresponding author
Head and Neck cancer (HNC) is one of the most prevalent and lethal cancer globally. The incidence of tobacco-induced HNC is gradually increasing in low and middle income countries. Among the various causative factors associated with HNCs, tobacco and alcohol play synergistic effect and are frequentl…
Nov 2018 DOI 10.14302/issn.2572-3030.jcgb-18-2428
Shilpi GuptaCorresponding author
Head and neck cancers (HNCs) are the most prevalent and aggressive type of cancers. Genetic, epigenetic, environmental and viral risk-factors are associated with HNC carcinogenesis. Persistent infection of oncogenic human papillomaviruses (HR-HPVs) represent distinct biological, molecular and epigen…
Sep 2017 DOI 10.14302/issn.2572-3030.jcgb-17-1737
J. O OgunbiyiCorresponding author
Scientific review, Supervisory, slides evaluation and final review
Objective P16INK4a and Ki-67 are adjuncts to current histological assessment of cervical biopsies in identifying cases that require strict follow up and prompt intervention. This study aimed to evaluate P16INK4a and Ki-67 expression in squamous intraepithelial and other benign cervical lesions. Meth…
Jul 2016 DOI 10.14302/issn.2381-862X.jwrh-15-806
Badr AbdullGaffarCorresponding author
Background and Objectives: The prevalence of abnormal cervical cytology in morbidly obese women using ThinPrep® liquid-based Pap Test™ and HPV DNA Test™ is unknown. We aimed to investigate whether women with morbid obesity have a higher frequency of abnormal Pap smears compared with nonobese women,…