Open Access Pub publishes peer-reviewed, free-to-read open-access articles. Showing
articles matching Genetics — open any to read the full text,
or download the PDF or XML.
Mar 2024 DOI 10.14302/issn.2689-4602.jes-24-4982
Jeffrey O. HendersonCorresponding author
Mammalian Rbm45 is predominately expressed in neuronal tissue and is integral in brain development and neuronal differentiation under physiological conditions. Dysregulation of Rbm45 has been strongly associated with neurodegenerative disorders in humans and can drive hepatocellular carcinoma throug…
Feb 2022 DOI 10.14302/issn.2379-8572.joa-22-4072
Pier Mario BiavaCorresponding author
This translational paper discusses differentiation‑stage factors from zebrafish embryos as epigenetic regulators with potential to reverse neurosensory hearing loss. It outlines experimental evidence, delivery concepts, and research gaps.
Apr 2020 DOI 10.14302/issn.2574-4518.jsdr-20-3161
Karim SedkyCorresponding author
Delayed sleep phase syndrome (DSPS) is a circadian rhythm disorder where individuals experience difficulty modifying the time they go to sleep and wake up in response to environmental changes. The circadian rhythm itself is regulated by a variety of clock genes, and various other genes (e.g., AA-NAT…
Dec 2019 DOI 10.14302/issn.2694-1198.jge-19-3079
A.N. VolobuevCorresponding author
The problem of natural selection against recessive homozygotes in a population is investigated. It is shown that natural selection of mutant alleles linked with the Х-chromosome in a population at women is described by the nonlinear differential equation of the third order. The order of the differen…
Mar 2018 DOI 10.14302/issn.2639-3166.jar-18-1987
Prem NarainCorresponding author
The scientific and technological interventions for attaining precision in plant genetics and breeding since Mendel’s discovery of genetic laws have been critically reviewed in terms of cloning technology and reverse genetics, chip technology, genetically modified organisms and CRISPR-based gene edit…
May 2015 DOI 10.14302/issn.2379-7835.ijn-14-603
Kenneth LundstromCorresponding author
Epigenetic mechanisms based on DNA methylation, histone modifications and RNA interference have recently showed important association to the development of a wide variety of diseases such as cancer, cardiovascular, metabolic, skin, autoimmune diseases and neurologic disorders. In the context of prev…
Apr 2022 DOI 10.14302/issn.2372-6601.jhor-22-4133
Xin QingCorresponding author
Background Monoclonal gammopathy of undetermined significance (MGUS) and chronic myeloid leukemia (CML) are diseases of different lineages. The diagnosis of both MGUS and CML in the same patient is a rare occurrence and has not been reported in much literature. Case Presentation We describe a 56-yea…
Mar 2021 DOI 10.14302/issn.2329-9487.jhc-21-3742
Tesfaye SisayCorresponding author
Cardiovascular disease is actually a major cause of mortality, illness and hospitalization worldwide. Several risk factors have been identified that are strongly associated with the development of cardiovascular disease. Public prevention strategies have relied predominately on managing environmenta…
Mar 2020 DOI 10.14302/issn.2575-1212.jvhc-20-3234
Fabrizio di VirgilioCorresponding author
Aim of the Research The aim of this study is to analyze a group of dogs of different breeds affected by osteosarcoma (OSA), to document any prevalence of this primary bone neoplasia in breeds that are phylogenetically close and to help with further research human medicine, as a model of study for pr…
Feb 2020 DOI 10.14302/issn.2639-3166.jar-20-3185
Giorgio MasoeroCorresponding author
Four strains of Arbuscular Mycorrhizal (AM) biofertilizer fungi, combined with two potato cultivars, were in-field tested in a four-replicate arrangement in a factorial experiment. As far as general combinability is concerned, cv. Agria was more responsive to different inocula (yield +5.56%, P 0.02)…
Jun 2019 DOI 10.14302/issn.2688-5328.ijp-19-2731
Xiang WeiCorresponding author
The rise of epigenetics provides a new idea for studying the regulation of chronic pain-related genes and synaptic plasticity. External environmental stimuli can regulate BDNF genes through different epigenetic modifications. The epigenetic changes of the BDNF gene can affect the expression of its m…
Aug 2018 DOI 10.14302/issn.2689-4602.jes-18-2229
George MikhailovskyCorresponding author
A historical and conceptual review traces how evolutionary theory has expanded from classical selection to modern syntheses incorporating development, epigenetics, and systems thinking. Implications for research and science communication are discussed.
May 2018
Ioannis AlatsathianosCorresponding author
Genetics alone cannot thoroughly expound the environmental impact on the molecular complexity of the endocrine system. Epigenetic-induced alteration in gene expression has emerged as a way in which environmental compounds may exert endocrine effects. The environmental compounds that interfere with n…
Aug 2017 DOI 10.14302/issn.2379-7835.ijn-17-1710
Mazlum ÇöpürCorresponding author
Background: High number of patients suffering from autism spectrum disorders utilize dietary intervention methods, especially gluten-free/casein-free diet. In contrast with its’ extensive usage no sufficient and consistent data exist to support its’ efficiency and safety. Objective: The main aim of…
Feb 2017 DOI 10.14302/issn.2372-6601.jhor-17-1423
YA Dei-AdomakohCorresponding author
Departments of Haematology
Background: The diagnosis and treatment outcomes of Non- Hodgkin Lymphoma’s (NHL) in resource poor countries in the absence of routine molecular studies and immunohistochemistry is challenging. Methods: A retrospective review of case folders of NHL patients aged13 years and above. Information obtain…