Open Access Pub publishes peer-reviewed, free-to-read open-access articles. Showing
articles matching cell — open any to read the full text,
or download the PDF or XML.
Dec 2017 DOI 10.14302/issn.2766-8630.jrnm-17-1770
Emad Y. MoawadCorresponding author
The aims of this study are to investigate the variation in the mechanical behaviour of the primary cancer from cancer relapse, and measuring the therapeutic resistance acquired by cancer relapse. A431-cultured cells were irradiated for 7 months until 85 Gy. Then, a selected single cell was left to g…
Nov 2017 DOI 10.14302/issn.2471-2175.jdrt-17-1760
Madhuri BhandaruCorresponding author
Metastatic melanoma is a very deadly type of skin cancer with poor prognosis and low 5-year survival rates. Until recently, patients with metastatic melanoma had very few treatment options, which only included dacarbazine and aldesleukin. In 2011, the first checkpoint blocker, ipilimumab was approve…
Sep 2017 DOI 10.14302/issn.2324-7339.jcrhap-17-1694
R Berete CoulibalyCorresponding author
Introduction: Squamous cell carcinomas of the conjunctiva (SCC) are rare neoplasia but have a high rate of increase and a high rate of mortality, especially when they occur in the context of Human Immunodeficiency Virus (HIV) infection. The objective of this study was to establish an epidemiological…
Jul 2017 DOI 10.14302/issn.2574-4372.jesr-17-1611
Zhen HeCorresponding author
Neural stem cell activity at least partially accounts for the postweaning development of the sexually dimorphic nucleus of the preoptic area (SDN-POA) and estrogen selectively mobilizes neural stem cells in the 3rd ventricle stem cell niche (3VSCN). Here, we examined the expression of estrogen recep…
Jul 2017 DOI 10.14302/issn.2639-1716.jn-17-1495
Michael J GonzalezCorresponding author
Diets high in unsaturated fatty acids, especially those containing high levels of linoleic acid, e.g., corn oil, enhance mammary gland tumorigenesis in experimental animals. In contrast, diets high in long-chain polyunsaturated fatty acids such as eicosapentaenoic (EPA) and docosahexaenoic (DHA), e.…
Jun 2017 DOI 10.14302/issn.2690-4721.ijcm-17-1533
Soon Hoe Ho BSc (Hon)Corresponding author
This essay draws on recent evidences from SIV vaccination studies in rhesus macaques to argue for the potential importance of HIV-1-specific CD8+ T cells restricted by the non-classical major histocompatibility complex, HLA-E, in controlling HIV-1 replication. It then seeks to present a possible met…
Jun 2017 DOI 10.14302/issn.2470-0436.jos-17-1442
Ozkan KocamisCorresponding author
Objective: Determining the effects on macular ganglion cell layer thickness in patients using isotretinoin by utilization of optical coherence tomography. Material and Methods: Sixty eyes of 30 patients using isotretinoin and 60 eyes of 30 control group patients in the same age range were included i…
May 2017 DOI 10.14302/issn.2470-0436.jos-17-1453
Jie ZhangCorresponding author
Purpose: High intraocular pressure (IOP) is known to result in retinal ganglion cell (RGC) loss, both with chronically raised intraocular pressure (such as with glaucoma) and with acute raises in pressure (due to injury or acute angle closure). Because IOP is often raised during ocular surgery, the…
Mar 2017
Mats RembergerCorresponding author
This article examines how HLA‑DRB1 allele mismatching influences outcomes after hematopoietic stem cell transplantation. It reviews graft‑versus‑host disease risk, engraftment, and survival metrics in the context of donor matching strategies. The findings support careful allele‑level typing to optim…
Feb 2017 DOI 10.14302/issn.2574-4372.jesr-16-1380
Huafeng WeiCorresponding author
General anesthetics (GAs) are widely used for various essential surgical or medical procedures. Recent studies implicate the GAs has dual effects of neuroprotection and neurotoxicity on neurogenesis with unclear mechanisms. This minireview summarizes recent studies on GAs mediated effects on neuroge…
Feb 2017 DOI 10.14302/issn.2574-4372.jesr-16-1382
Bhuvnesh K. SharmaCorresponding author
Stem cell research is now emerging as most exciting and promising area of modern biomedical research which has enormous potential for easing suffering for many diseases such as Parkinson’s, Alzheimer’s, Diabetes,Cancer and many more. This is now recognized most promising alternate therapeutic choice…
Jan 2017 DOI 10.14302/issn.2574-4372.jesr-16-1327
Cristina ZaniniCorresponding author
Stem cell-based regenerative therapy can be considered an innovative approach for curing dental caries. Pulp stem cells from human exfoliated deciduous teeth (SHEDs) represent a source of committed cells for generating odontoblasts in vitro; however, SHEDs are not easy to obtain and are limited in q…
Jan 2017 DOI 10.14302/issn.2379-8572.joa-16-1399
Muhammet fatih topuzCorresponding author
Aim: The relation between inflammation and cancer has been known since the 19th century. However, investigations on the pathogenesis and pathophysiology of this relation have begun recently. It was demonstrated that increased neutrophil/lymphocyte ratio is a poor prognostic factor in some malignanci…
Dec 2016 DOI 10.14302/issn.2372-6601.jhor-16-1330
Isacco FerrariniCorresponding author
Immune thrombocytopenia (ITP) is a rare but well-recognized post-allogeneic hematopoietic stem cell transplant (HSCT) autoimmune complication for which a standard treatment approach is lacking. Herein we report on an adult patient affected by high-risk acute myeloid leukemia (AML) who developed a po…
Nov 2016 DOI 10.14302/issn.2574-4526.jddd-16-1311
M DarouichiCorresponding author
Department of radiology
Adenosquamous carcinoma of the stomach (ASCS) is extremely rare with less than one hundred cases published in the world literature. It is defined by combined adenocarcima and squamous cells carcinoma of the stomach. ASCS is clinically aggressive and has a poor prognosis, even when discovered at an e…
Jul 2016 DOI 10.14302/issn.2379-7835.ijn-16-986
S YarakCorresponding author
Abstract: Several researchers have suggested that a targeted diet for reducing theadipose tissue may interfere with the severity of cellulite. Others emphasize that the diet composition seems to play a more relevant role than the calorie profile for weight loss and cellulite control. Objective: The…
Jul 2016 DOI 10.14302/issn.2574-4372.jesr-16-1055
Matthew B. JensenCorresponding author
Human-induced pluripotent stem cells (HiPSCs) demonstrate promise in their ability to differentiate into neural cells and ultimately replace the cell types and thereby brain tissue damaged by stroke. This may diminish cognitive impairment due to stroke. Prior to transplantation, an appropriate scaff…
Jun 2016 DOI 10.14302/issn.2372-6601.jhor-16-1125
Jun-ya KatoCorresponding author
Senescence is a powerful mechanism that prevents the development of tumors in vivo; however, once tumors are formed, most are refractory to senescence in response to oncogenic stress. Therefore, a novel pathway leading to senescence is required. We herein demonstrated that the cell cycle regulator C…
Jun 2016 DOI 10.14302/issn.2471-2175.jdrt-15-836
Samaneh AbiriCorresponding author
Cellulitis is an acute, spreading pyogenic inflammation of the dermis and subcutaneous tissue, usually complicating a wound, ulcer, or dermatosis. Inappropriate diagnosis of cellulitis is a problem and would need prospective rather than retrospective studies to quantify the extent. There is one nati…
May 2016 DOI 10.14302/issn.2381-862X.jwrh-15-914
Minakshi RohillaCorresponding author
A case report of compound heterozygous hemoglobin SD disease presenting as sickle crisis during pregnancy. The discussion covers transfusion, pain control, and peripartum care.