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Nov 2017 DOI 10.14302/issn.2641-7669.ject-17-1725
Obaid FaroonCorresponding author
The Agency for Toxic Substances and Disease Registry (ATSDR) lists cadmium as one of its priority hazardous substances. The agency conducted a comprehensive literature review of cadmium and used the information to develop a toxicological profile that identified the full range of health effects assoc…
Nov 2017 DOI 10.14302/issn.2576-9383.jhhr-17-1816
Abu Syed Md. MosaddekCorresponding author
Background: Disorders of lipid metabolism are manifested by elevation of the plasma concentration of the various lipid and lipoprotein fractions and the result, predominantly cardiovascular diseases. Lipid research clinic’s coronary primary prevention trial has provided useful information on the red…
Aug 2017 DOI 10.14302/issn.2688-5328.ijp-17-1600
Hristina ZlatanovaCorresponding author
The objective of our study was to evaluate the analgesic and anti-inflammatory activity, as well as possible organ toxicity of 2-3-3-methyl-pentanoic acid (compound 3d), a newly synthesized pyrrolic derivative, structurally similar to Celecoxib. Antinociception was assessed using animal pain models…
Jul 2017 DOI 10.14302/issn.3070-5835.jcpn-17-1562
Mary V. SeemanCorresponding author
Second-generation antipsychotics have relatively recently become available in long-acting intramuscular formulations (LAIs) and have been receiving a substantial amount of pharmaceutical industry promotion on the grounds that they improve treatment adherence in patients with psychotic illness. LAIs…
Jul 2017 DOI 10.14302/issn.2471-2140.jaa-17-1630
Aholia Jean- Baptiste AdépoCorresponding author
Laboratoire de Toxicologie et Hygiène Agro-industrielle, UFR Sciences Pharmaceutiques et Biologiques, Université Félix Houphouët-Boigny, BP V 34, Abidjan, Côte d’Ivoire
Introduction: Aflatoxins are cytotoxic andserve as one of the key risk factors of hepatocellular carcinoma. Currently, plants and extract are widely used as potential scavenging substances for the detoxification of mycotoxins. Thus, this study aims to investigate the activity of the crude ethanolic…
Jun 2017 DOI 10.14302/issn.2377-2549.jndc-17-1439
Syed Najmul Hejaz AzmiCorresponding author
The effectiveness of atorvastatin calcium in lowering cholesterol is dose-related. It is available in 10, 20, 40, and 80 mg film coated tablets. In order to ensure quality, safety and efficacy of tablets in formulations, the objective of this presented work was to develop a new high performance liqu…
May 2017 DOI 10.14302/issn.2576-2818.jfb-17-1435
Teresa WiesakCorresponding author
The objective of this study was to investigate whether percentage of mature oocytes retrieved from ovaries stimulated with long agonist or multi-dose antagonist protocols affect the implantation, clinical pregnancy and live birth of ICSI (Intracytoplasmic sperm injection) cycles. The 654 cycles of a…
Feb 2017 DOI 10.14302/issn.2476-1710.jdt-16-1346
Roman D. DeikoCorresponding author
Theaim of study is to evaluate antidepressant-like activity of the new peptidergic neuroprotectoracetyl-(D-Lys)-Lys-Arg-Arg-amide, homologous of ACTH15-18 primary amino acids sequence, that demonstrates nootropic and neuroprotective properties. Using Porsolt swimming test (PST) efficacy of tetrapept…
Aug 2016 DOI 10.14302/issn.2574-4496.jtc-16-1129
Frieda SilvaCorresponding author
Objective: Radiation exposure to the general public and patients undergoing diagnostic or therapeutic procedures is of great concern, especially to the medical community. Revision of Nuclear Regulatory Commission rules several years ago yield new recommendations for the administration of therapeutic…
Aug 2016 DOI 10.14302/issn.2474-9273.jbtm-16-1151
Guoqiang XingCorresponding author
Oxidative stress mediated neural cell death is thought to be involved in the progression of secondary cell injury following brain trauma. Agents that can block oxidative stress-related injury could be potential therapies for TBI. Resveratrol, a polyphenol found in plants and red wine, is cytoprotect…
May 2016 DOI 10.14302/issn.2574-450X.jom-16-1039
Mary V. SeemanCorresponding author
Over the last three decades, an epidemic of obesity has markedly affected patients suffering from mental illnesses such as schizophrenia. Antipsychotic medications used to treat schizophrenia are considered as major culprits. The aim of this review is to first consider risk factors, to then outline…
May 2016 DOI 10.14302/issn.2470-5020.jnrt-15-908
Yasemin KayaCorresponding author
Objective: We aimed to investigate homocysteine levels and carotid intima-media thickness (CIMT) in Parkinson’s Disease (PD), to determine relationship of these parameters and as well as to determine whether CIMT in patients with PD was associated to age, disease duration, age of disease onset, stag…
Feb 2016 DOI 10.14302/issn.2473-1005.jdoi-15-912
Selcuk M. OzbekCorresponding author
A healthy 55-year-old man was referred to the Department of Endodontics, Oral and Dental Healthy Hospital, Eskişehir suffering from pain and paraesthesia in the left lower lip and chin.A panoramic radiograph revealed the presence of broken endodontic instrument beyond the apex of the mandibular left…
Feb 2016 DOI 10.14302/issn.2379-7835.ijn-16-924
Nimmathota ArlappaCorresponding author
Objectives: Vitamin A deficiency (VAD) among the rural pre-school children in India is continues to be a major nutritional problem of public health significance, even after the implementation of national vitamin A prophylaxis programme for more than four decades. The aim of the study was to assess t…
Dec 2015 DOI 10.14302/issn.2470-0436.jos-15-818
Nimmathota ArlappaCorresponding author
Purpose: Vitamin A deficiency (VAD) is still a major nutritional problem of public health importance among the rural pre-school children in India, even after the implementation national vitamin A prophylaxis programme for prevention of nutritional blindness and ICDS have been in operation for more t…
Oct 2015 DOI 10.14302/issn.2379-8572.joa-15-691
Hany Abdel RahmanCorresponding author
Background. Nasopharyngeal carcinoma (NPC) is a rare disease in the pediatric age group; it represents 1% of all pediatrics malignancies, however, it is the predominant malignancy arising in the nasopharynx in this age group. Although NPC is a chemo-radiosensitive disease yet, the optimal dose of ra…
May 2015 DOI 10.14302/issn.2644-0105.jbfb-14-547
Gianluca Di LuigiCorresponding author
Background: Scientific research is constantly expanding our knowledge of nutritional needs in pregnancy and lactation. In June 2014 the Food and Drug Administration (FDA) and the Environmental Protection Agency (EPA) issued draft-revised advice encouraging pregnant women, those who might become preg…
Jun 2013 DOI 10.14302/issn.2324-7339.jcrhap-12-174
Rajesh RadhakrishnanCorresponding author
Radhakrishnan Rajesh M.Pharm, Asst Professor (Senior Grade), Department of Pharmacy Practice, Manipal College of pharmaceutical Sciences, Manipal University, Manipal- 576 104, Karnataka, India.
Background: In India, Human immunodeficiency (HIV) infected patients with highly active antiretroviral therapy (HAART) are at higher risk of developing adverse drug reactions (ADRs). Objectives: The aim of this study was to characterize the pattern of use of HAART, occurrence, incidence, severity an…
Jan 2013 DOI 10.14302/issn.2328-0182.japst-12-99
Wolfgang C KorteCorresponding author
To date, platelet aggregation studies have not been formally evaluated in persons receiving Etodolac, a preferential cyclooxygenase-2 (COX-2) inhibitor. Our purpose was to investigate the influence of Etodolac in therapeutic (analgesic) doses (300 mg every 12h) on platelet aggregation as compared to…