Search results for “CLI”

Dietary Advice on Prescription (DAP). A Pedagogical Model for Better Dietary Habits Tested in a Two-Year Randomized Clinical Trial. 

There Is A Gap Between What We Know And What We Do, Such As Knowing What We Should Eat And What We Actually Eat, A So-Called “Attitude/Behavior Gap”. It Is Not Necessary To Go From A Change In Attitude To A Change In Behavior. It Is Possible To Do The Opposite; In Other Words, It Is Possible To Go F…

Supporting Quality Data Systems:  Lessons Learned from Early Implementation of Routine Viral Load Monitoring at a Large Clinic in Lilongwe, Malawi

Successful viral load programs rely on the presence of data systems and high quality of patient data. Using a cohort of 49 patients at Partners in Hope, a large, urban HIV clinic in Malawi, we performed a quality improvement assessment of a new viral load program with a focus on accuracy of data col…

Functional, Structural and Contextual Analysis of a Variant of Uncertain Clinical Significance in BRCA1: c.5434C->G (p. Pro1812Ala)

Interpreting variants of uncertain significance (VUS) for their effect on protein function, and therefore for the risk of developing cancer, has become a challenge in clinical practice for genetic counselling services. The present work combines structural bioinformatics and systems biology based mat…

Evaluation of Vitamin D Deficiency in Patients with Chronic Liver Disease and Its Clinical Significance

Introduction: Vitamin D deficiency has been reported highly prevalent in Chronic liver disease (CLD) and there is an emerging interest to explore the relationship of vitamin D deficiency and severity of various types of CLD. Aim: To evaluate vitamin D level in patients with various type of CLD and c…

Trends of Diabetes in Children and Adolescents in Pediatric Endocrinology Clinic and Clinical Pediatric Diabetes Center at Al Baha Central Hospital in Saudi Arabia

Objectives This study describes and compares the epidemiological criteria of children with diabetes from 2007 to 2014. Methods A prospective study conducted with 372 children with diabetes mellitus. An access program was used for data collection, and SPSS 17 was used to analyses the results. Results…

Analysis of Effects of Kale Powder Consumption among Subjects with Potential Metabolic Syndrome: A Prospective Single-Arm Clinical Study

Objective: The prospective intervention study was conducted to investigate the effects of kale powder (Kale juice mixed with water or milk) consumption on metabolic syndrome in subjects with potential metabolic syndrome. Method: In Arita-cho, 149 male and female subjects with potential metabolic syn…

Prevalence of Campylobacter Species in Out-Patients and Pregnant Women Attending Government Clinics in Sokoto State, Nigeria

Campylobacter infection has been detected in poultry processors at live bird markets in Sokoto, however the prevalence of Campylobacter species in more diverse group of the population is uncertain. For this purpose, 292 human fecal swabs from patients in four Government Hospitals in Sokoto State wer…

Evaluation of the Impact of Clinical, Functional and Social Factors on the Readmission of Patients with Pluripathologies

Purpose Hospital readmission of patients with pluripathologies is frequent and costly. This study describes the impact of patients’ pluripathologies, functional capacity and social complexity on readmissions during a 12-month period following hospital discharge. Methods A prospective cohort study. M…

A High Volume, User-Friendly Immunization Clinic in Vellore, India: A Model for Urban Hospitals

The Expanded Program on Immunization (EPI) in India delivers vaccines under its policy, through government hospitals, health centers and outreach clinics. However, the national average full immunization coverage is stagnating at about 70%. The days and times of clinics are not always convenient for…

The Early Use of Blinding in Therapeutic Clinical Research of Neurological Disorders

We sought to identify early uses of blinding in therapeutic clinical trials of neurological disorders by multiple search methods. A 1784 report by Benjamin Franklin and others described the evaluation of the use of Mesmerism to treat neurological and other syndromes including headache and epilepsy,…

Clinical and Immunological Beneficial Effects of Phyto V7 Consumption by HIV-1 Seropositive Individuals

Phytochemicals (PHT) are a large group of biologically active plant chemicals that may have positive effects on human health such as immune system stimulation, down regulation of inflammatory responses, radical scavenging activities, cell repair function, and antibacterial and antiviral activity. In…

Subjective and Objective Actigraphic Sleep Monitoring and Psychopathology in a Clinical Sample of Patients with Night Eating Syndrome, with and Without Binge Eating Behaviors

Introduction: Night Eating Syndrome (NES) is a phenomenon combining aspects of both sleeping disorders and Eating Disorders (EDs). To the best of our knowledge, few studies to date have examined NES among patients with EDs. None examined ED patients with and without NES in clinical settings by compa…

The Toxicity of Iodinated Radiographic Contrast Agents in the Clinical Practice

Iodinated radiographic contrast agents (IRCA) are pharmaceutical agents used to improve the visibility of internal organs and structures in X-ray based imaging techniques. However, IRCA may have adverse unwanted effects, ranging from a mild inconvenience, such as itching, to a life-threatening emerg…

Laryngeal Tissue Engineering using Rabbit Adipose Derived Stem Cells in Fibrin: A Pre-Clinical Model

Vocal fold scarring is a clinical problem without reliable treatment. Tissue engineering of a vocal fold replacement is an exciting potential treatment for vocal fold scars that involve multiple layers of the vocal fold. Human adipose-derived stem cells (ASC) were previously used to produce a promis…

Evaluation of Recruitment Approaches for the HPTN 052 Clinical Trial of HIV Serodiscordant Couples in Rural Western Kenya

Recruitment of couples is important for study success. The multi-centered HPTN 052 clinical trial was designed to evaluate whether immediate versus delayed use of ART by HIV-infected individuals would reduce transmission of HIV to their HIV-uninfected partners. The objective of this study was to ret…

Demographics, Clinical Profile and Outcome among the HIV Infected Persons Hospitalized in the HAART Era in Barbados.

Background: HAART has resulted in significant decline in morbidity and mortality from HIV. However, it is unclear if the trends have continued in the current HAART era. An understanding of healthcare utilization patterns is important for optimization of care and resource allocation. We examined the…

Psychosocial Characterization of HIV Clients with Potential to be Change Agents for HIV Prevention in Uganda

New research suggests that people living with HIV have the potential to be strong advocates for HIV prevention by passing on HIV prevention messages within their social networks. However, there is a paucity of research into the nature and prevalence of HIV prevention behaviours engaged in by HIV cli…

RETRACTED: Multidisciplinary doctor’s clinical practice, confident and difficulties to diagnose, manage and care for dementia in remote area hospital

Technical Evaluation of Automated Left Ventricular Quantification in Cardiac Magnetic Resonance Imaging: Comparison with Manual Reference Measurements

Background Automated left ventricular (LV) quantification may reduce the manual post-processing burden of cardiac magnetic resonance (CMR) imaging but requires evaluation against manual reference measurements before routine clinical use. Purpose To evaluate automated CMR post-processing for LV quant…

Impact of Shift Work on Heart Health: Do Shift-Working Healthcare Workers Have Higher Cardiovascular Risk Than Non-Shift Healthcare Workers? A Narrative Review

Background: Shift work is unavoidable in continuous healthcare delivery, but whether shift-working healthcare staff carry greater cardiovascular risk than their non-shift colleagues has not been synthesised endpoint by endpoint. Objective: To examine, for each cardiovascular risk factor and each cli…