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Feb 2019 DOI 10.14302/issn.2572-3030.jcgb-19-2581
Ashraf KhanCorresponding author
We report the case of a 75 year-old female with past history of ampullary adenocarcinoma presenting with a rapidly enlarging breast mass, initially misclassified on fine needle aspiration as a probable sarcoma, which was ultimately diagnosed as melanoma on resection in the absence of a known cutaneo…
Dec 2018 DOI 10.14302/issn.2641-5526.jmid-18-2488
Juan Luis Fernández-MartínezCorresponding author
Background: Triple Negative Breast Cancer (TNBC) is a type of breast cancer with very bad prognosis. Predicting the histological grade (HG) and the lymph nodes metastasis is crucial for developing more suitable treatment strategies. Methods: We present the main clinical and pathological variables to…
Dec 2018 DOI 10.14302/issn.2574-4526.jddd-18-2521
Rizvan Yagubovich AbdullaievCorresponding author
Introduction: Ultrasound study of locally advanced gastric cancer that has spread to adjoining tissue and lymph nodes. This tumor can be associated with T2 to T4 stages of cancer. A “Locally advanced gastric cancer” is a tumor, which may be categorized as ‘resectable’ cancer when compared with M1 ad…
Oct 2018 DOI 10.14302/issn.2372-6601.jhor-18-2396
Anwar Tawfik AminCorresponding author
Although surgery is the main treatment for solid tumors, it could enhance the growth and metastasis of minimal residual cancer. In this review article we have discussed the perioperative changes in cancer cells and surrounding environment as well as the alterations in the immune system. Several tria…
Aug 2018 DOI 10.14302/issn.2691-8862.jvat-18-2209
Mohammad ShayestehpourCorresponding author
A concise review of oncolytic virotherapy covering viral engineering, tumor selectivity, and immune modulation. It assesses preclinical and clinical progress and discusses combinations with immunotherapies to enhance antitumor effects.
Mar 2018 DOI 10.14302/issn.2639-1716.jn-18-1993
W. Kurtis ChildersCorresponding author
Cardiovascular disease and lung cancer are two of the most common causes of death in the United States. The cardioprotective benefits of statin class drugs is predominantly mediated through the inhibition of 3-hydroxy-3-methylglutaryl CoA (HMG-CoA) reductase, decreasing available mevalonate, and thu…
Mar 2018
Loris RizzelloCorresponding author
The crusade against cancer has a new army: immunotherapy. The rational design is very simple, but brilliant at the same time. Extract the patients T-cells, reprogram them in vitro for the expression of highly specific receptors against cancer, perfuse them back to the patient. As a result, T-cells a…
Mar 2018
Xiaoping LiuCorresponding author
An important use of proteomics data from Mass Spectrometry (MS) is the classification of tumor types with respect to peptides in specific cancer types. It is highly critical to find an optimal set of markers among specific cancer peptides whose expression can be clinically utilized to build assays f…
Feb 2018 DOI 10.14302/issn.2372-6601.jhor-18-1938
Elsayed Mostafa AliCorresponding author
Neuropilins are transmembrane glycoproteins that act as receptors for vascular endothelial growth factors (VEGF) and are involved in the process of tumor angiogenesis. Its importance in hematological malignancies such as acute leukemia (AL) remains to be elucidated. The aim of this study was to eval…
Feb 2018 DOI 10.14302/issn.2639-1716.jn-18-1965
Jamie T. CaraccioloCorresponding author
Lipomatous tumors are among the most common primary musculoskeletal neoplasms affecting both pediatric and adult patient populations. Patient age, tumor location, and imaging features all contribute to the differential diagnosis of musculoskeletal tumors. Tumors identified outside of common patient…
Dec 2017 DOI 10.14302/issn.2766-8630.jrnm-17-1770
Emad Y. MoawadCorresponding author
The aims of this study are to investigate the variation in the mechanical behaviour of the primary cancer from cancer relapse, and measuring the therapeutic resistance acquired by cancer relapse. A431-cultured cells were irradiated for 7 months until 85 Gy. Then, a selected single cell was left to g…
Oct 2017 DOI 10.14302/issn.2576-182X.jbsc-17-1809
Gabriele RonchettiCorresponding author
Rupture of an intracranial aneurysm may cover for a long time clinical and radiological signs of a coexistent tumor. We report the delayed diagnosis of glioblastoma in a 65-years old female with recent history of subarachnoid hemorrhage. In the literature are described few similar cases: we briefly…
Oct 2017 DOI 10.14302/issn.3070-5657.je-17-1513
Volkan GELENCorresponding author
Changes to proinflammatory cytokines as a result of gestational diabetes mellitus (GDM), and the pregnancy complications that these changes can cause, are of vital importance to the effective prevention and optimal management. Interleukin-6 (IL-6), interleukin-1 beta (IL-1β), and tumor necrosis fact…
Sep 2017 DOI 10.14302/issn.2324-7339.jcrhap-17-1694
R Berete CoulibalyCorresponding author
Introduction: Squamous cell carcinomas of the conjunctiva (SCC) are rare neoplasia but have a high rate of increase and a high rate of mortality, especially when they occur in the context of Human Immunodeficiency Virus (HIV) infection. The objective of this study was to establish an epidemiological…
Aug 2017 DOI 10.14302/issn.2575-1212.jvhc-17-1574
Gabriela Noronha de ToledoCorresponding author
Periosteal osteosarcoma is an uncommon primary malignant bone tumor in dogs and humans. This type of tumor is one of the four variants of osteosarcoma. The main feature is a superficial lesion without evidence of bone marrow involvement. The treatment usually performed is limb amputation. There is i…
Aug 2017 DOI 10.14302/issn.2572-3030.jcgb-14-383
Adrian MaurerCorresponding author
Meningiomas are the most common intracranial tumor in humans. The heterogeneity of these tumors lends difficulty to the genetic, epigenetic, and molecular changes that occur in meningioma pathogenesis, progression, and recurrence. Current de facto classification schemes are based on histologic evalu…
Jul 2017 DOI 10.14302/issn.2372-6601.jhor-17-1473
R RaacheCorresponding author
Laboratoire des cytokines et NO Synthases (FSB-USTHB), Université des Sciences et de la Technologie Houari Boumediene (USTHB), Alger, Algérie
Objective: This study aimed to evaluate the relation of Lactate dehydrogenase (LDH) levels with stage of the disease and it role in monitoring tumor response to therapy in lymphoma patients. Methods. LDH levels were evaluated on 65 diagnosed Algerian children and compared to healthy control. Results…
Jul 2017 DOI 10.14302/issn.2575-1212.jvhc-17-1586
Mayara Caroline ROSOLEMCorresponding author
The mammary tumor is one of the most common cancer in female dogs and, at the present days, there is a big focus on the study of the relation between this kind of tumor in animals and the cells that stay around them, like the inflammatory cells. The objective of this study was to evaluate and show w…
Jul 2017 DOI 10.14302/issn.2639-1716.jn-17-1499
Walid Abu ArabCorresponding author
Non-small cell lung cancer is a major health problem worldwide. Surgery is still the mainstay of treatment especially in early stages of the disease. Despite the fact that surgery is the potentially curative treatment, the recurrence and mortality rates are still high specifically with more advanced…
May 2017 DOI 10.14302/issn.2470-5020.jnrt-17-1503
Moussa TOUDOU DAOUDACorresponding author
Introduction Bacterial meningitis complicates rarely pituitary macroadenomas. The aim of our systematic review is to study the features of the association between bacterial meningitis and pituitary macroadenoma. Methods We conducted a literature search in both MedLine and Google Scholar database fro…