Search results for “cancer”

About 100 results in articles

Open Access Pub publishes peer-reviewed, free-to-read open-access articles. Showing articles matching cancer — open any to read the full text, or download the PDF or XML.

Molecular and Cell Biological Considerations in the Initiation and Development of Sporadic Non-Hereditary Solid Cancers  

Aug 2018 DOI 10.14302/issn.2572-3030.jcgb-18-2183
Vladimir F. NiculescuCorresponding author

This paper reviews the state of cancer research in the post-mutation era. It presents cancer as a highly complex disease viewed differently by scientists from various research fields. Histopathologists considered cancer as a disease of cell differentiation, cancer cell biologists overestimated the c…

Investigation and Analysis on Mental Health State of Breast Cancer Patients in China

Jun 2018 DOI 10.14302/issn.2574-612X.ijpr-18-2110
Wei XuCorresponding author

Purpose: There are nearly 170,000 new cases of breast cancer in China every year, and this number is showing an increasing trend. Mental health plays an important role in promoting the physical rehabilitation of patients. Therefore, attention paid to their psychological problems needs to be reinforc…

Journal of Neoplasms Open Access

Statins and Lung Cancer: A Review of Current Literature

Mar 2018 DOI 10.14302/issn.2639-1716.jn-18-1993
W. Kurtis ChildersCorresponding author

Cardiovascular disease and lung cancer are two of the most common causes of death in the United States. The cardioprotective benefits of statin class drugs is predominantly mediated through the inhibition of 3-hydroxy-3-methylglutaryl CoA (HMG-CoA) reductase, decreasing available mevalonate, and thu…

Ovarian Cancer Identification Based on Feature Weighting for High-Throughput Mass Spectrometry Data

Mar 2018
Xiaoping LiuCorresponding author

An important use of proteomics data from Mass Spectrometry (MS) is the classification of tumor types with respect to peptides in specific cancer types. It is highly critical to find an optimal set of markers among specific cancer peptides whose expression can be clinically utilized to build assays f…

Efficacy of The Immunotargeting Therapeutic Antibody Trastuzumab in HER2-Positive Advanced Gastric Cancer: A Meta-Analysis

Feb 2018
Jincheng ZengCorresponding author

Gastric cancer is one of the most common types of cancer in the world, usually diagnosed at an advanced stage. Despite the advances in specific anticancer agents' development, the survival rates remain modest, even in early stages. HER2 overexpression was identified on 15% - 20% of gastric cancer pa…

Metabolic Correction Therapy as Adjuvant Treatment for Breast Cancer Patients: A Case Report

Jan 2018
Michael J GonzalezCorresponding author

Breast cancer is the most common cancer in women worldwide. In the United States, is the second leading cause of cancer deaths in women. In Puerto Rico between 2008 and 2012, breast cancer was the most diagnosed type of cancer and the leading cause of cancer deaths among women. This is a case of 54…

First Evidences of Epithelial-Mesenchymal Transition and Cancer Stem-Cell Phenotype Acquisition in Dermo-Epidermal Junction of BPV-Infected Neoplasms

Dec 2017 DOI 10.14302/issn.2576-6694.jbbs-17-1869
Rita de Cassia StoccoCorresponding author

Introduction Bovine papillomavirus (BPV) is the etiological agent of bovine papillomatosis, infectious and neoplastic disease, characterized by the presence of multiple papillomas that can regress spontaneously or to persist and progress to malignancies when in association with environmental cofacto…

Cellular Mechanics and Therapeutic Resistance of the Cancer Relapse

Dec 2017 DOI 10.14302/issn.2766-8630.jrnm-17-1770
Emad Y. MoawadCorresponding author

The aims of this study are to investigate the variation in the mechanical behaviour of the primary cancer from cancer relapse, and measuring the therapeutic resistance acquired by cancer relapse. A431-cultured cells were irradiated for 7 months until 85 Gy. Then, a selected single cell was left to g…

Study of VCAM-1 Gene Expression in Normal and Tumoral Tissues in Patients with Colorectal Cancer

Nov 2017 DOI 10.14302/issn.2576-6694.jbbs-17-1744
Frouzandeh MahjoubiCorresponding author

Aim: Colorectal cancer is one of the most commonly diagnosed cancers in the world. Cell adhesion molecules play an important role in the progression of various cancers. It has been shown that the high level expression of some Cell adhesion molecule could be a new diagnostic factor for several cancer…

Deficits in Psycho-Oncological Care among Turkish Immigrant Women with Breast Cancer in Germany – An Interview Study.

Sep 2017 DOI 10.14302/issn.2574-612X.ijpr-17-1746
Jacob SpallekCorresponding author

Objective: Aim of this study was to assess appraisal and utilization of psycho-oncological care of Turkish female breast cancer patients in Germany. The presented results are part of a larger study about care of female German and Turkish cancer patients in Germany (4B-study). Methods: In this qualit…

Markers for Significant or High-Grade Prostate Cancer in Patients over 75 Years Undergoing Prostatic Biopsy

Aug 2017
Vahudin ZugorCorresponding author

Purpose: To show the increased necessity of routine prostate biopsy in men older than 75 years and to identify markers, which reliably indicate the presence of a prostate cancer (PCa), we evaluate several different parameters from elderly patients. Methods: 196 patients over 75 years were included i…

Combined Therapy Versus Usual Care in the Treatment of Depressed Cancer Patients with Pain

Aug 2017 DOI 10.14302/issn.2574-612X.ijpr-17-1604
Andrea BoveroCorresponding author

Objective To compare Brief Adlerian Psychodynamic Psychotherapy (B-APP) plus venlafaxine versus venlafaxine plus usual care on pain and depressive symptomatology of depressed patients with cancer pain. Methods A total of 100 patients with pain and mood depression, according to DSM IV-TR, were random…

Left Brachiocephalic Vessel Venous Tumor Thrombus in a Laryngeal Cancer Patient Detected with PET-CT Imaging

Aug 2017 DOI 10.14302/issn.2379-8572.joa-17-1672
Pelin Ozcan KaraCorresponding author

Accurate diagnosis of tumor thrombus and distinguishing benign thrombus from tumor thrombus avoid unnecessary anticoagulant treatment of oncological patients and it is important for patient management. In this case report, the role of FDG PET/CT in the presentation of a suspicious tumor thrombus in…

Compliance to Company Based Colorectal Cancer Screening in Germany using Fecal Immunochemical Test (FIT) - Results of Almost Half a Million FIT Tests

Aug 2017 DOI 10.14302/issn.2471-7061.jcrc-17-1624
Claudia PieperCorresponding author Institute for Medical Informatics, Biometry und Epidemiology, University Hospital of Essen, Hufelandstraße 55, 45122 Essen, Germany,

Background Despite the existence of the statutory early cancer detection program in Germany and the removal of financial barriers, which is frequently reported in the literature to be the main obstacle in screening, uptake of colorectal cancer screening remains quite low. The campaign for colorectal…

Journal of Neoplasms Open Access

The Role of Heparin in Lung Cancer

Jul 2017 DOI 10.14302/issn.2639-1716.jn-17-1499
Walid Abu ArabCorresponding author

Non-small cell lung cancer is a major health problem worldwide. Surgery is still the mainstay of treatment especially in early stages of the disease. Despite the fact that surgery is the potentially curative treatment, the recurrence and mortality rates are still high specifically with more advanced…

Correlates of Mental Health in Survivors of Colorectal Cancer: The Influence of Individual, Family, and Community Level Factors

Aug 2016 DOI 10.14302/issn.2474-9273.jbtm-16-1105
Elizabeth J. SiembidaCorresponding author

An often neglected factor in the examination of the mental quality of life of survivors of colorectal cancer is the role of family and community level resources and support. The aim of this study was to develop a deeper understanding of the influence of family and community level resources over and…

Predictors Of Colon Cancer in Patients Referred to a Gastroenterologist for Iron Deficiency

Jul 2016 DOI 10.14302/issn.2574-4526.jddd-16-1203
Mark R. BorgaonkarCorresponding author

Background: Iron deficiency is a common reason for referral to a gastroenterologist. Objective: To identify predictors of colorectal cancer in patients referred to a gastroenterologist for iron deficiency. Methods: This was a retrospective review of consecutive patients referred to one of two gastro…

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