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Aug 2019
Irma KhachidzeCorresponding author
Objective Antisocial behavior (ASB) in children and youth is public health problem in Georgia. Nevertheless, there has been no systematic study the risk factors for ASB that could counteract on ASB development. To prevent ASB development and acceleration the understanding of biological (assessment o…
Jul 2019 DOI 10.14302/issn.2474-3585.jpmc-19-2947
Minoo AsadzandiCorresponding author
Objectives Death is the only definitive phenomenon in life, and everyone is sure that it will happen in the future. Based on the philosophical perspective, the concept of death differs in different cultures. The purpose of this study was “explaining the difference between the concept of death from t…
Jul 2019 DOI 10.14302/issn.2640-6403.jtrr-19-2946
Snehasis JanaCorresponding author
Multiple organ dysfunction syndrome or failure is one of the major concerns against healthcare services in order to maintain the normal function. The present study aimed to explore the impact of the Biofield Energy Treated test formulation on the function of vital organs such as bones, heart, liver,…
Jun 2019 DOI 10.14302/issn.2688-5328.ijp-19-2731
Xiang WeiCorresponding author
The rise of epigenetics provides a new idea for studying the regulation of chronic pain-related genes and synaptic plasticity. External environmental stimuli can regulate BDNF genes through different epigenetic modifications. The epigenetic changes of the BDNF gene can affect the expression of its m…
May 2019 DOI 10.14302/issn.2644-1101.jhp-19-2766
Francesco CrespiCorresponding author
Cholecystokinin (CCK) is found in high concentrations in cortical and limbic structures including the amygdala of rodents, and evidence has been gathered supporting a role for CCK in the neurobiology of anxiety. A variety of animal models have been used to study a central state of fear or anxiety, s…
Apr 2019 DOI 10.14302/issn.2998-4211.jalr-19-2658
C S SandeepCorresponding author
Research Scholar, CET, Trivandrum, University of Kerala
Alzheimer’s Disease (AD) is one amongst the overwhelming types of dementia that distresses the brain nerve cells leading to a perpetual loss in memory and creating a lot of difficulties for the family members in caretaking. The prediction of the disease at an earlier stage is a common problem. The m…
Feb 2019 DOI 10.14302/issn.2470-5020.jnrt-18-2554
Ladislav VolicerCorresponding author
Background Controversy exists about definition of agitation and especially about inclusion of aggression as a part of agitation in people with dementia. Methods Papers describing neurobiological indices related to behavioral symptoms of dementia were reviewed. Papers comparing indices in persons exh…
Jan 2019
Excessive variability in behavioral performance and neuronal activation is a common finding in studies of schizophrenia. Recent evidence suggests that this may be due to an imbalance in the ratio of excitation to inhibition in brain function, or E/I imbalance. We used computational modeling of visua…
Jan 2019 DOI 10.14302/issn.2641-5526.jmid-18-2529
Juan Luis Fernández-MartínezCorresponding author
Discrimination of case-control status based on gene expression differences has potential to identify novel pathways relevant to neurodegenerative diseases including Parkinson’s disease (PD). In this paper we applied two different novel algorithms to predict dysregulated pathways of gene expression a…
Dec 2018 DOI 10.14302/issn.2379-7835.ijn-18-2501
Paolo MainardiCorresponding author
In the last few years, gut microbiota has been identified to be an essential mediator in health and disease. In fact, it interacts with various organs and systems in the body, including brain, lung, liver, bone, cardiovascular system, and others. Microbiota-derived metabolites such as the short chai…
Dec 2018 DOI 10.14302/issn.2578-8590.ipj-18-2524
Francesco CrespiCorresponding author
The pineal gland constitutes a major neuroendocrine organ in the brain. By mean of its neurohormone melatonin it transduces exogenous signals such as circadian and seasonal variations of light and temperature into proper hormonal changes which adjust and adapt internal endocrine functions. Alteratio…
Sep 2018
Kleber Santiago Freitas e SilvaCorresponding author
Epilepsy comprises a series of chronic neurological disorders characterized by recurrent seizures. Over 50 million people are affected by epilepsy worldwide. In addition, genetic components capable of predicting epilepsy predisposition and antiepileptic drugs response would lead to the development o…
Jul 2018 DOI 10.14302/issn.2577-2279.ijha-18-2179
Abdelmonem A. HegazyCorresponding author
Cranial vault is the case surrounding the brain. Its structure differs in newborns than in adults in some aspects. Such differences should be clear for both health and family members. Moreover, the anatomy and embryology of fetal skull take a little attention in the previous literature and textbooks…
May 2018 DOI 10.14302/issn.2474-7785.jarh-18-2099
Win K. ThuCorresponding author
Overview: Dementia is a serious brain disease that impacts negatively in several areas of patient’s functioning. Depression has a strong link with dementia and is part of the behavior and psychological symptoms (BPSD). Behavior management for depression is recommended as a first-line psychological t…
Apr 2018 DOI 10.14302/issn.2326-0793.jpgr-18-2004
Pervez AnwarCorresponding author
Human proteome project was revolutionized about 40 years ago with purpose of summarizing whole proteomic data at one place. It was launched after human genome project to map and observe all proteins. The goal related proteomic study is to draft the entire human proteome in disease diagnosis by using…
Feb 2018
Ba T TaCorresponding author
Military Hospital 103
Lung transplantation is an established treatment option for patients of end-stage lung diseases. Leading indications include chronic obstructive pulmonary disease, idiopathic pulmonary fibrosis and bronchiectasis, pulmonary arterial hypertension. Living donor lung transplantation (LDLT) was indicat…
Feb 2018 DOI 10.14302/issn.2576-6694.jbbs-18-1887
Nathan S. HagemanCorresponding author
The application of bilateral alternating stimulation in tactile (BLAST) form technology, a non-invasive, somatosensory-based method, has been shown to modulate the electrical activity of brain networks that mediate the stress response, resulting in a stress-reducing effect in individuals with high r…
Jan 2018 DOI 10.14302/issn.2470-5020.jnrt-17-1926
Simon NagelCorresponding author
Since the first description in 2013, 39 cases of anti-DPPX-encephalitis have been described. Main features of this autoimmune encephalitis characterized by antibodies against the potassium-channel-associated regulatory protein DPPX are gastrointestinal symptoms, cognitive dysfunction and signs of CN…
Apr 2017 DOI 10.14302/issn.2572-5424.jgm-17-1482
Morris H BaslowCorresponding author
Canavan disease (CD) is a globally occurring but rare human spongiform leukodystrophy that is associated with inborn errors affecting the activity of aspartoacylase (ASPA), an enzyme highly expressed in oligodendrocytes that hydrolyzes N-acetylaspartate (NAA). Lack of ASPA activity is associated wit…
Apr 2017 DOI 10.14302/issn.2474-7785.jarh-17-1483
Jon DorfmanCorresponding author
Background: Discharge disposition planning begins at admission and is frequently one of the first questions posed to healthcare providers by patients and families. We hypothesized that pre-injury functional status would predict discharge disposition. Methods: We linked prospective data from the Worc…