Open Access Pub publishes peer-reviewed, free-to-read open-access articles. Showing
articles matching Metabolic — open any to read the full text,
or download the PDF or XML.
Jul 2016 DOI 10.14302/issn.2572-5424.jgm-16-1066
Sanjay HarrisonCorresponding author
Lactic acidosis is a condition commonly encountered in the hospital setting particularly in critically ill patients and is very often used as a diagnostic adjunct when encountering cases of ischaemia or other hypoperfusion states. Despite its use many clinicians have long forgotten the biochemical m…
Jun 2016
Arup Ratan BandyopadhyayCorresponding author
Earlier studies reported significant association of obesity, hypertension and Type2 Diabetes Mellitus (T2DM). Genetic and many disease-associated alleles have been identified through GWAS and applied to T2DM and indicated roles of renin-angiotensin system (RAS) in insulin signaling pathway and insul…
Jun 2016 DOI 10.14302/issn.2374-9431.jbd-15-647
Asmat NawazCorresponding author
Diabetes is a metabolic disorder that results in human body due to insulin deficiency, insulin resistance or both. In the management of diabetes, glucose monitoring technology has been used for the last three decades. The aim of this review article is to describe concise and organized information ab…
Jun 2016 DOI 10.14302/issn.2572-5424.jgm-16-1028
Morris H BaslowCorresponding author
N-acetylaspartylglutamate (NAAG) is the highest concentration dipeptide present in brain. It is found primarily in neurons but its function is unclear. NAAG is synthesized by neurons from N-acetylaspartate and glutamate (Glu), maintained at mM concentrations and is released non-synaptically to extra…
May 2016 DOI 10.14302/issn.2574-450X.jom-16-1039
Mary V. SeemanCorresponding author
Over the last three decades, an epidemic of obesity has markedly affected patients suffering from mental illnesses such as schizophrenia. Antipsychotic medications used to treat schizophrenia are considered as major culprits. The aim of this review is to first consider risk factors, to then outline…
Jan 2016 DOI 10.14302/issn.2379-8572.joa-15-814
Mohammad FarhadiCorresponding author
Background and Objective: The etiological factors for nasal polyps include infection, inflammation or an imbalance of a metabolic pathway. This study was designed to compare serum Helicobacter pyloriantibodies and H. pylori–DNAs between cases of nasal polyp and controls (nasal fracture). Patients an…
Jun 2015 DOI 10.14302/issn.2574-4372.jesr-14-607
Michael E. GeuszCorresponding author
Cancer is influenced by the ability of cells to maintain circadian rhythms in molecular and metabolic processes. Disturbance of the underlying circadian timing mechanism in circadian clock cells leads to a higher frequency and more rapid progression of cancer. Cancer stem cells with properties of em…
May 2015 DOI 10.14302/issn.2379-7835.ijn-14-603
Kenneth LundstromCorresponding author
Epigenetic mechanisms based on DNA methylation, histone modifications and RNA interference have recently showed important association to the development of a wide variety of diseases such as cancer, cardiovascular, metabolic, skin, autoimmune diseases and neurologic disorders. In the context of prev…
Feb 2014 DOI 10.14302/issn.2372-6601.jhor-13-346
Chloe E. ClaphamCorresponding author
Targeting cell metabolism is a therapeutic approach which has been used for the treatment of cancers with high levels of proliferation. Inhibition of metabolic processes in cancer cells has shown synergy with current therapeutic options to reduce refractory disease and relapse. In contrast, chronic…
May 2013 DOI 10.14302/issn.2324-7339.jcrhap-12-140
Leona DoldCorresponding author
Analyzing SNPs linked to fatty liver disease, this study finds no association with HAART‑related hepatic steatosis in HIV patients. The work underscores the multifactorial nature of antiretroviral toxicity and points to metabolic and pharmacologic contributors beyond common variants.