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Jan 2018 DOI 10.14302/issn.2577-2279.ijha-17-1903
Reinhilde JacobsCorresponding author
The aim of the present study was to compare mandibular neurovascular canal anatomy in human and great apes by using cone beam computed tomography (CBCT). The anatomical variability of mandibular neurovascular canals (mandibular, incisive and lingual canals) of 129 modern humans and great apes (Homo,…
Oct 2017 DOI 10.14302/issn.2572-5424.jgm-17-1609
Jean-claude PEREZCorresponding author
DUF1220 proteins regions show the largest Homo-Sapiens lineage-specific increase in copy number of any protein-coding region in the human genome and map principally to 1q21.1. DUF1220 deletions have been associated with microcephaly and macrocephaly, respectively. DUF1220 copy number has been linked…
Sep 2017 DOI 10.14302/issn.2324-7339.jcrhap-17-1694
R Berete CoulibalyCorresponding author
Introduction: Squamous cell carcinomas of the conjunctiva (SCC) are rare neoplasia but have a high rate of increase and a high rate of mortality, especially when they occur in the context of Human Immunodeficiency Virus (HIV) infection. The objective of this study was to establish an epidemiological…
Sep 2017 DOI 10.14302/issn.2832-4048.jsm-17-1621
Yuri A. KoryakCorresponding author
The effects of long-term space flight on human triceps surae (TS) muscle function and electromechanical delay (EMD) have been investigated. Voluntary and electrically evoked contractions of the TS were obtained from 7 male cosmonauts 30 days before and 3 days after landing. For all cosmonauts the is…
Jul 2017 DOI 10.14302/issn.2639-1716.jn-17-1495
Michael J GonzalezCorresponding author
Diets high in unsaturated fatty acids, especially those containing high levels of linoleic acid, e.g., corn oil, enhance mammary gland tumorigenesis in experimental animals. In contrast, diets high in long-chain polyunsaturated fatty acids such as eicosapentaenoic (EPA) and docosahexaenoic (DHA), e.…
Apr 2017 DOI 10.14302/issn.2572-5424.jgm-17-1482
Morris H BaslowCorresponding author
Canavan disease (CD) is a globally occurring but rare human spongiform leukodystrophy that is associated with inborn errors affecting the activity of aspartoacylase (ASPA), an enzyme highly expressed in oligodendrocytes that hydrolyzes N-acetylaspartate (NAA). Lack of ASPA activity is associated wit…
Jan 2017 DOI 10.14302/issn.2574-4372.jesr-16-1395
Tetsuro WakatsukiCorresponding author
Calcium (Ca2+) plays a central role in regulating many biological processes in the cell from muscle contraction to neurotransmitter release. The need for reliable fluorescent calcium indicator dyes is of vast importance for studying many aspects of cell biology as well as screening compounds using p…
Jan 2017 DOI 10.14302/issn.2574-4372.jesr-16-1327
Cristina ZaniniCorresponding author
Stem cell-based regenerative therapy can be considered an innovative approach for curing dental caries. Pulp stem cells from human exfoliated deciduous teeth (SHEDs) represent a source of committed cells for generating odontoblasts in vitro; however, SHEDs are not easy to obtain and are limited in q…
Dec 2016 DOI 10.14302/issn.2329-9487.jhc-16-1338
TRUE ConsortiumCorresponding author
Although inaccurate, non-reproducible blood pressure values can result from non-standardized assessments, recommended approaches to standardize blood pressure measurement are often not followed in research studies. An expert consensus of national and international health and scientific organizations…
Oct 2016 DOI 10.14302/issn.2572-3030.jcgb-16-1276
Takuma HayashiCorresponding author
Human uterine leiomyosarcoma (LMS) is neoplastic malignancy that typically arises in tissues of mesenchymal origin. The identification of novel molecular mechanism leading to human uterine LMS formation and the establishment of new therapies has been hampered by several critical points. We earlier r…
Jul 2016 DOI 10.14302/issn.2473-1005.jdoi-16-999
Francesco AmatoCorresponding author
Purpose: The aim of the study was to analyze the spatial relationship between the sinus floor and the alveolar bone of maxillary premolars and molars in order to assess the amount of basal bone available for immediate extraction placement of endosseous implants. Materials and Methods: All the cone-b…
Jul 2016 DOI 10.14302/issn.2574-4372.jesr-16-1055
Matthew B. JensenCorresponding author
Human-induced pluripotent stem cells (HiPSCs) demonstrate promise in their ability to differentiate into neural cells and ultimately replace the cell types and thereby brain tissue damaged by stroke. This may diminish cognitive impairment due to stroke. Prior to transplantation, an appropriate scaff…
Apr 2016 DOI 10.14302/issn.2575-7881.jdrr-15-863
Miguel A. FuertesCorresponding author
It was, previously, reported that the specific pattern of the compositional features of particular human-mouse orthologs defining in human two clusters, named C2 and C5, are present in different clusters in mouse. Since, thus, these orthologs can harbor a significant number of nucleotide differences…
Feb 2016 DOI 10.14302/issn.2372-6601.jhor-15-896
Vladimir ZaichickCorresponding author
Objectives: Adenocarcinoma of prostate is an internationally important health problem of the man, particularly in developed countries. The aim of this exploratory study was to evaluate whether significantchanges in the prostatic tissue levels of calcium (Ca), potassium (K), and magnesium (Mg) as an…
Feb 2016 DOI 10.14302/issn.2574-4496.jtc-15-838
Daniel ChristopheCorresponding author
Thyroid transcription factor-1 (TTF-1) is known to play key roles in thyroid organogenesis, in thyroid cell proliferation and in the expression of genes involved in thyroid differentiated function. Many human thyroid cancer cell lines keep producing TTF-1 despite the loss of differentiated gene expr…
Oct 2015 DOI 10.14302/issn.2470-0436.jos-14-571
Takuya SHIBACorresponding author
Purpose: To describe a new functional magnetic resonance imaging (fMRI) method for measuring the influence of regular astigmatism, both against-the-rule (ATR) and with-the-rule (WTR), on the human visual cortex. Setting: Department of Ophthalmology, Jikei University School of Medicine, Tokyo, Japan.…
Aug 2015 DOI 10.14302/issn.2372-6601.jhor-15-666
Vladimir ZaichickCorresponding author
Objectives: To clarify the role of trace elements in the etiology and the pathogenesis of the chondrosarcoma, a non-destructive neutron activation analysis with high resolution spectrometry of long-lived radionuclides were performed. Methodology: The silver (Ag), cobalt (Co), chromium (Cr), iron (Fe…
Jun 2014 DOI 10.14302/issn.2372-6601.jhor-13-379
Takuma HayashiCorresponding author
Sarcomas are neoplastic malignancies that typically arise in tissues of mesenchymal origin. The identification of novel molecular mechanisms leading to sarcoma formation and the establishment of new therapies has been hampered by several critical factors. Human uterine leiomyosarcoma (Ut-LMS) develo…
Jul 2013 DOI 10.14302/issn.2326-0793.jpgr-13-207
Joanna FlorosCorresponding author
Surfactant protein A (SP-A) plays a number of roles in lung host defense and innate immunity. There are two human genes, SFTPA1 and SFTPA2, and evidence indicates that the function of SP-A1 and SP-A2 proteins differ in several respects. To investigate the impact of SP-A1 and SP-A2 on the alveolar ma…
Jun 2013 DOI 10.14302/issn.2324-7339.jcrhap-12-174
Rajesh RadhakrishnanCorresponding author
Radhakrishnan Rajesh M.Pharm, Asst Professor (Senior Grade), Department of Pharmacy Practice, Manipal College of pharmaceutical Sciences, Manipal University, Manipal- 576 104, Karnataka, India.
Background: In India, Human immunodeficiency (HIV) infected patients with highly active antiretroviral therapy (HAART) are at higher risk of developing adverse drug reactions (ADRs). Objectives: The aim of this study was to characterize the pattern of use of HAART, occurrence, incidence, severity an…