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Mar 2022 DOI 10.14302/issn.2572-3030.jcgb-22-4121
Pierre Diaga SARRCorresponding author
Laboratory of Clinical Cytology, Cytogenetics and Reproduction Biology, Aristide Le Dantec Hospital, Dakar-Senegal
Introduction Genomic mutations in TP53 gene in association with etiological risk factors have been associated with oral carcinogenesis. Herein, we screened for genomic variants of TP53 predisposing to oral cancers in Senegalese patients. Methodology 88 patients with confirmed diagnostic were recruit…
Feb 2022 DOI 10.14302/issn.2689-5773.jcdp-22-4065
Vladimir ZaichickCorresponding author
Thyroid malignant nodules (TMNs) are the most common endocrine cancer. The etiology and pathogenesis of TMNs must be considered as multifactorial. Diagnostic evaluation of TMNs represents a challenge, since there are numerous benign and malignant thyroid disorders that need to be exactly attributed.…
Feb 2022
Ricardo GobatoCorresponding author
Using samples of small cell lung tumors, a research team led by biologist Dr. Raymond discovered two new ways to induce tumor cell death. By activating ferroptosis, one of two subtypes of tumor cells can be targeted: first, iron-dependent cell death due to oxidative stress, and second, oxidative str…
Aug 2021 DOI 10.14302/issn.2326-0793.jpgr-21-3917
Leonid TarassishinCorresponding author
50 years ago the Enzyme Immunoassay Enzyme-Linked Immunosorbent Assay, mostly known as ELISA was developed. This is a powerful but simple method that is very widely used in the diagnostic practice, as well as in biomedical research. During this time a number of ELISA modification were developed that…
Aug 2021 DOI 10.14302/issn.2689-5773.jcdp-21-3890
Zakaria MERADCorresponding author
Splenic hydatid cyst is very rare, caused by the parasite echinococcus granulosus. Humans are considered an accidental intermediate host in the development of the parasite cycle. It poses a diagnostic dilemma with other cystic masses despite improved medical imaging techniques often requiring explor…
Jul 2021 DOI 10.14302/issn.2689-5773.jcdp-21-3905
Francisco Javier Torres GómezCorresponding author
This essay reflects on the craft of diagnostic pathology, using color and pattern as a narrative lens. Through case vignettes, it illustrates how morphology, staining, and visual reasoning translate into clinical answers. The perspective emphasizes communication, uncertainty management, and the huma…
May 2021 DOI 10.14302/issn.2690-4721.ijcm-21-3835
Milagrosa MontesCorresponding author
Objective Real-time surveillance of SARS-CoV-2 variants of concern (VOC) is of essential public health importance. Rapid Antigen Detection Tests (RAgDT) have become first-line COVID-19 diagnostic methods in many regions, but this strategy can hamper the surveillance of the virus variants due to thei…
Apr 2021 DOI 10.14302/issn.2372-6601.jhor-21-3801
Xin QingCorresponding author
Lennert lymphoma (lymphoepitheloid lymphoma) is an extremely rare variant of peripheral T-cell lymphoma, not otherwise specified. Here we report a case of Lennert lymphoma diagnosed in a 57-year-old woman. She had a three-year history of waxing and waning lymphadenopathy with a rapid increase in siz…
Apr 2021 DOI 10.14302/issn.2470-0436.jos-21-3710
David G. Diciano Jr.Corresponding author
Introduction Large impaled object in the orbital region causes severe visual impact and requires specialized care within the shortest time possible. Objectives In this case report, we discussed the approach and management of a patient that presented with a penetrating orbitocranial injury, from mana…
Apr 2021 DOI 10.14302/issn.2692-1537.ijcv-21-3741
Sahilu AssegidCorresponding author
Background Ethiopia confirmed its 1st case of COVID-19 on Friday 13th February 2020. The burden increased dramatically by August/2020. The conditions that led to this rise were not reviewed. Objective To exploreCOVID-19 related phenomena in Ethiopia during 2019-2020. Materials and Methods Review of…
Mar 2021 DOI 10.14302/issn.2575-1212.jvhc-21-3767
Faysal Abdishakur HassanCorresponding author
Antibodies and antibody fragments, especially single-domain antibodies known as nanobodies, are important tools in diagnostics, research, and therapeutics. In a conventional antibody, light and heavy chains contribute to the formation of the antigen binding site. In addition to conventional antibodi…
Feb 2021 DOI 10.14302/issn.2690-0904.ijoe-21-3727
Vajiheh KeshavarzCorresponding author
Background and Purpose Providing health care is the basic right of people(1). Diagnostic radiology is one of the main procedures in health care services and proper benefiting from this technology is brought only under well planning and management(1). Supervision of the available condition and its co…
Oct 2020 DOI 10.14302/issn.2576-6694.jbbs-20-3517
Camille S.U. DOSSOUCorresponding author
Background of the Study African countries are facing frequent blackout. Thus in sub Saharan region, due to frequent power cut, the laboratory professionals find sometimes difficulty to carry out earlier diverse diagnostic tests. Objective The aim of this work is to evaluate the feasibility of enzy…
Oct 2020 DOI 10.14302/issn.2641-4538.jphi-19-3115
Charles D MwalimuCorresponding author
Africa Region has the highest burden of malaria with an estimated of 3.5 million more malaria cases in 2017 compared 212 million cases in reported in 2016. Data collected from 2015 to 2017, shown no global progress in reducing malaria cases. In Mainland Tanzania, malaria control interventions have s…
Jun 2020 DOI 10.14302/issn.2574-4526.jddd-20-3410
M. DarouichiCorresponding author
Glandular-cystic bladder cystitis is a rare, benign non-tumor condition, preferentially located on the area of the bladder trigone and can simulate a malignant tumor. It is a benign reactive metaplasia of the bladder submucosa, characterized by hyperplasia of the islets of Von Brunn and cystic. It i…
Jun 2020 DOI 10.14302/issn.2688-5328.ijp-20-3386
Carlo PrunetiCorresponding author
How to define pain? One of the most accredited definition is certainly “An unpleasant sensory and emotional experience associated with actual or potential tissue damage, or described in terms of such damage" (IASP (International Association for the Study of Pain - 1986) and World Health Organization…
Jun 2020 DOI 10.14302/issn.2691-8862.jvat-20-3320
Amin AtaieCorresponding author
By increase the incidence of infection of coronavirus disease 2019 (COVID-19), diagnostic factors for early identification of high-risk individuals are important. On the other hand, more infections are in older patient, comorbidities, and male patients. Identification of components that related to s…
Jun 2020 DOI 10.14302/issn.2372-6601.jhor-20-3372
Fatih OzcelikCorresponding author
Immune thrombocytopenia currently called under its’ new name, immune thrombocytopenic purpura (ITP) is a disease characterized by thrombocytopenia, in which the body attacks its own platelets due to the disorders in immune system. The pathophysiology of this disease includes increased platelet destr…
May 2020 DOI 10.14302/issn.2693-1176.ijgh-20-3353
Lucio MangoCorresponding author
In recent decades was observed a gradual increase in the detection of thyroid nodules in the adult population. Given the increase in prevalence of nodules, a similar trend to the growth in the incidence of thyroid cancers was found. The reasons for this increased incidence for thyroid cancer are con…
May 2020 DOI 10.14302/issn.2692-1537.ijcv-20-3341
Igor KlepikovCorresponding author
A timely review discusses acute pneumonia in the context of COVID‑19, covering diagnostics, imaging patterns, supportive care, and evolving therapeutics. It highlights uncertainties and priorities for coordinated research and clinical pathways.