Search results for “genome”

About 24 results in articles

Open Access Pub publishes peer-reviewed, free-to-read open-access articles. Showing articles matching genome — open any to read the full text, or download the PDF or XML.

Branch Retinal Vein Occlusion in Factor V Leiden Mutation

Jun 2015 DOI 10.14302/issn.2470-0436.jos-14-528
Sanjay SrinivasanCorresponding author Ophthalmology and Visual Sciences, Khoo Teck Puat Hospital, Singapore

A previously healthy 25 year old Chinese male presented with left eye blurring of vision and was diagnosed to have left eye branch retinal vein occlusion. Initial blood investigations and thrombophilia screen were negative. The patient subsequently improved with observation and conservative manageme…

Oxidative Telomere Attrition, Nutritional Antioxidants and Biological Aging

Jan 2015 DOI 10.14302/issn.2379-7835.ijn-14-606
Michael J. GladeCorresponding author

Telomeres are strings of DNA that are not themselves genes but that extend every chromosome beyond its last gene. Terminal telomeres are sacrificed during every mitotic event in human cells (“telomere attrition”), preserving the functional genome despite the “end replication problem.” However, the “…

Bioinformatics of Metabolomics in Diabetes Mellitus Type 2

Oct 2014 DOI 10.14302/issn.2374-9431.jbd-13-212
Hamdy Ahmad SliemCorresponding author

Diabetes mellitus type 2 (DMT2) is a complex polygenic disorder. DMT2 is a result of insulin resistance and destruction of pancreatic β-cell or dysfunction. Therefore, glucose builds up in the bloodstream, leading to nerve damage, blindness, organ failures and sometimes death. Recently, some recentl…

Eukaryotic Signature Proteins

Dec 2012 DOI 10.14302/issn.2326-0793.jpgr-12-101
Jian HanCorresponding author

Eukaryotic Signature Proteins (ESPs) are proteins that delineate the eukaryotes from the archaea and bacteria. They have no recognisable homologues in any prokaryotic genome, but their homologues are present in all main branches of eukaryotes. ESPs are thus likely to have descended from ancient prot…

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