Search results for “drug”

About 100 results in articles

Open Access Pub publishes peer-reviewed, free-to-read open-access articles. Showing articles matching drug — open any to read the full text, or download the PDF or XML.

Regulation of Expression of Reactive Oxygen Intermediates During Plasmodium Infection to Reduce Immunopathology Provides a Possible Antioxidant Adjuvant to Enhance Anti-Malarial Drug Therapy

Aug 2017 DOI 10.14302/issn.2690-4721.ijcm-17-1676
Andrew W. Taylor-RobinsonCorresponding author

Malaria is a mosquito-transmitted infectious disease caused by intracellular protozoan parasites of the genus Plasmodium. In the absence of prompt and appropriate treatment contraction of primary infection by a human being often represents a medical emergency since it may progress rapidly to life-th…

Novel N-Pyrrolylcarboxylic Acid Derivative as a Potential New Analgesic and Anti-Inflammatory Drug

Aug 2017 DOI 10.14302/issn.2688-5328.ijp-17-1600
Hristina ZlatanovaCorresponding author

The objective of our study was to evaluate the analgesic and anti-inflammatory activity, as well as possible organ toxicity of 2-3-3-methyl-pentanoic acid (compound 3d), a newly synthesized pyrrolic derivative, structurally similar to Celecoxib. Antinociception was assessed using animal pain models…

Trends and inducing factors for illicit drug use in Grenada: Epoch 2001 – 2009.

Nov 2016 DOI 10.14302/issn.2474-9273.jbtm-16-1304
Afolami FagoralaCorresponding author

Objective The psychosocial aspect of drug use is seldom researched in Caribbean nations. Drug use in the Caribbean has been on the rise since the 1990s. Statistical indicators have established evidence for the increased rates of illegal drug use. This study briefly reviewed these indicators and expl…

A Successful Vancomycin Treatment of Multidrug-Resistant MRSA-Associated Canine Pyoderma

Oct 2016 DOI 10.14302/issn.2471-2175.jdrt-16-1296
Luisa De MartinoCorresponding author

Case Report This report describes a case of diffuse pyoderma in a 10-year-old female dog with hypothyroidism. A previous treatment, without an early diagnosis, including cephalosporin associated with prednisolon resulted to be unsuccessfully. After clinical and microbiological examination in our lab…

Synthesis and Assessment of a New Tetrahydrogeraniol Derivative as Penetration Enhancer for Transdermal Drug Delivery

Oct 2016 DOI 10.14302/issn.2572-5424.jgm-16-1170
Gul Majid KhanCorresponding author

Background: Skin is one the most important sites for administration of drugs to obtain desired pharmacological effects either locally or through systemic bioavailability; and this has placed the transdermal route of drug delivery as an attractive and as one of the most innovative areas for conductin…

Current Status of Nonsteroidal Anti-Inflammatory Drugs in Colorectal Cancer Prevention

Jan 2015 DOI 10.14302/issn.2471-7061.jcrc-14-394
Petros C. PapagiorgisCorresponding author

This review synthesizes evidence on NSAIDs and colorectal cancer prevention. It balances chemopreventive efficacy against gastrointestinal and cardiovascular risks, and considers selective COX‑2 inhibitors, dosing, and candidate populations for risk‑benefit.

Evaluation of SterculiaUrens Gum as Novel Carrier for Oral Colon Targeted Drug Delivery System

Nov 2013 DOI 10.14302/issn.2328-0182.japst-12-119
Bipul NathCorresponding author

The purpose of the research is to evaluate Sterculiaurens gum as a carrier for oral colon targeted drug delivery system. Sterculia gum has been reported to have wide pharmaceutical applications such as tablet binder, disintegrant, gelling agent and as a controlled release polymer, but it has not bee…

Pattern of Use of Highly Active Antiretroviral Therapy Regimens and Pattern of Occurrence of Adverse Drug Reactions in an Indian Human Immunodeficiency Virus Positive Patients

Jun 2013 DOI 10.14302/issn.2324-7339.jcrhap-12-174
Rajesh RadhakrishnanCorresponding author Radhakrishnan Rajesh M.Pharm, Asst Professor (Senior Grade), Department of Pharmacy Practice, Manipal College of pharmaceutical Sciences, Manipal University, Manipal- 576 104, Karnataka, India.

Background: In India, Human immunodeficiency (HIV) infected patients with highly active antiretroviral therapy (HAART) are at higher risk of developing adverse drug reactions (ADRs). Objectives: The aim of this study was to characterize the pattern of use of HAART, occurrence, incidence, severity an…

Evaluation of Direct Cost of Adverse Drug Reactions to Highly Active Antiretroviral Therapy in Indian Human Immunodeficiency Virus Positive Patients

Dec 2012 DOI 10.14302/issn.2324-7339.jcrhap-12-71
Rajesh RadhakrishnanCorresponding author Radhakrishnan Rajesh M.Pharm, Asst Professor (Senior Grade), Department of Pharmacy Practice, Manipal College of pharmaceutical Sciences, Manipal University, Manipal- 576 104, Karnataka, India.

In India, interruptions to highly active antiretroviral therapy (HAART) are due to adverse drug reactions (ADRs) and no reports on the direct cost incurred in the management of ADRs to HAART are available. There is a need to study direct cost incurred with ADRs to HAART to explore the high economic…

Carbapenem-resistant Enterobacterales at a quaternary public hospital in Durban, KwaZulu-Natal: Ascertaining the clinical and molecular paradigm shift following COVID-19

Oct 2026 DOI 10.14302/issn.2690-4721.ijcm-26-6425
Nitesh BrijlalCorresponding author

Background Extensive carbapenem use has resulted in an increasing occurrence of difficult-to-treat resistant gram-negative bacteria (DTR-GNB), such as carbapenem-resistant Enterobacterales (CREs). The international antimicrobial resistance (AMR) landscape was profoundly impacted due to varying antib…

The Advantages of Employing the Immune Response Mediated by Immunoglobulins in Preclinical and Clinical Research: An Essential Review

Sep 2026
Yilkal Tariku BelayCorresponding author

Immunoglobulins, commonly known as antibodies, are glycoprotein molecules present on B lymphocytes and within the bloodstream. They are essential components of the immune response, as they detect the harmful molecules of test compounds and stimulate the immune system to manifest proportional counter…

Assessment of Syndemic Inter-relationships between Substance Use, Violence and HIV Risk Among Persons Seeking Emergency Care in Nairobi, Kenya

Jul 2026 DOI 10.14302/issn.2324-7339.jcrhap-26-6137
J. Austin LeeCorresponding author

Introduction Contemporaneous substance abuse, violence and HIV/AIDS risks (SAVA) result in synergistic negative impacts (syndemic effects). Presence of and risks for syndemic SAVA conditions are common among emergency department (ED) patients, however research on these inter-related processes is lim…

Apomorphine Subcutaneous Infusion is More Efficient Than foslevodopa/foscarbidopa Subcutaneous Infusion in the Treatment of Advanced Parkison´s Disease for the Spanish National Health System

May 2026 DOI 10.14302/issn.2641-4538.jphi-26-6161
J GonzalezCorresponding author

Objectives Motor fluctuations and non-motor disorders not manageable by first-line treatments in advanced Parkinson's disease require continuous dopaminergic stimulation strategies such as subcutaneous infusions of apomorphine (APO) or foslevodopa/foscarbidopa (FLD/FCD). A Budget Impact Analysis (BI…

Investigating Into Artificial Intelligence Trained Algorithms and Their Effectiveness in Addressing Female Infertility

Jan 2026
Kirandeep KaurCorresponding author

Background Female infertility has always been an issue and social stigma in India and it’s not only the matter of physical health of the female but also related to psychological health and the social status of the women. The diagnosis of this problem criterion requires medical symptoms for the condi…

Integrating Analgesic Doses and Pain Trend Analysis: A Novel Clinical Support System

Dec 2025 DOI 10.14302/issn.2688-5328.ijp-25-5402
Shih-Chieh YangCorresponding author

Background Prescribing appropriate analgesics with optimal dosages based on patients' pain severity is challenging, especially when multiple painkillers are involved. Tracking and analyzing the effectiveness of analgesics and their dosages over time is crucial for pain management. Existing systems l…

HIV-Associated Peripheral Neuropathy and Antiretroviral Therapy: A Prospective Study from a Tertiary Care Centre in South India

Dec 2025 DOI 10.14302/issn.2324-7339.jcrhap-25-5515
Anagha RaoCorresponding author

Background Peripheral neuropathy (PN) is a common and debilitating complication in people living with HIV (PLHIV). While HIV itself contributes to neuropathy, certain antiretroviral therapy (ART) drugs, particularly nucleoside reverse transcriptase inhibitors (NRTIs) such as stavudine (d4T) and zido…

Exploring the Nanomedicinal Features of Ayurvedic Bhasmas: Insights from Traditional Medicine

Oct 2025 DOI 10.14302/issn.3070-3360.ijco-24-5294
Rameshwar AdhikariCorresponding author

Ayurveda is a traditional and scholarly medical system practiced in South Asia since the Vedic period. It integrates science and philosophy to promote a healthy, happy and prosperous life. Ayurvedicbhasmas are classical formulations that contain non-toxic forms of metals and minerals, enriched with…

Artificial Intelligence in Healthcare: Enhancing Efficiency, Ensuring Equity, and Restoring Empathy

Sep 2025 DOI 10.14302/issn.2768-0207.jbr-25-5706
Yusuke NakamuraCorresponding author

Artificial Intelligence (AI) is emerging as a transformative force across many sectors, with healthcare representing both one of the most promising and most challenging areas of application. This review summarizes current and future applications of AI in healthcare, focusing on its potential to impr…

Frequently asked questions

Are these articles peer-reviewed?
Yes. Articles published at Open Access Pub go through single-blind peer review (double-blind on request) under an editorial board before publication.
Are the articles free to read?
Yes. Every article is open access — read the full text online for free and download the PDF or XML, with no paywall or subscription.
How do I cite an article?
Use the DOI shown on each result and on the article page; it is the permanent, citable link to the article.
How do I read or download an article?
Click "Read full text" to open the article HTML, or use the PDF / XML buttons on each card to download it.