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Oct 2015
Jennifer S. WooCorresponding author
The mitotic count is the most frequent reason for discordance between pathologists in modified Bloom and Richardson (mBR) scoring. Recently, the phosphohistone H3 (PHH3) immunohistochemical stain has been proposed as a potential surrogate marker for mitotic figures. This study examines the differenc…
Oct 2015 DOI 10.14302/issn.2379-8572.joa-15-691
Hany Abdel RahmanCorresponding author
Background. Nasopharyngeal carcinoma (NPC) is a rare disease in the pediatric age group; it represents 1% of all pediatrics malignancies, however, it is the predominant malignancy arising in the nasopharynx in this age group. Although NPC is a chemo-radiosensitive disease yet, the optimal dose of ra…
May 2015 DOI 10.14302/issn.2572-3030.jcgb-14-495
Ashraf KhanCorresponding author
Thyroid carcinomas encompass a wide spectrum ranging from differentiated thyroid carcinoma (DTC) to poorly differentiated (PDC) and anaplastic thyroid carcinoma (ATC). DTC of both follicular (FTC) and papillary (PTC) types can progress to PDC and AC. The aim of our study was to evaluate if there is…
May 2015 DOI 10.14302/issn.2470-0436.jos-14-527
Srinivasan SanjayCorresponding author
A 66 year old Chinese male with a medical history of hypertension, diabetes mellitus and hepatitis B carrier was diagnosed with hepatocellular carcinoma in 2009. He underwent treatment with selective internal radiation spheres and sorafenib, and multiple cycles of chemotherapeutic agents such as bev…
Feb 2015 DOI 10.14302/issn.2471-2175.jdrt-14-552
R. StrohalCorresponding author
Two pilot studies evaluate fractional Er:YAG laser microporation to enhance topical imiquimod delivery for actinic keratosis and basal cell carcinoma. The approach seeks to increase epidermal penetration while limiting systemic exposure. Early results suggest acceptable tolerability and lesion respo…
Jun 2026 DOI 10.14302/issn.2574-4496.jtc-26-6304
Omayma ElshafieCorresponding author
Objective To evaluate the treatment outcomes of patients with Differentiated thyroid cancer (DTC) who underwent total thyroidectomy followed by RAI therapy at the Sultan Qaboos Comprehensive Cancer Care and Research Centre (SQCCCRC) in Oman. Methods This is a retrospective observational clinical stu…
Feb 2026
Sunil SinghalCorresponding author
Objective The landscape of non-small cell lung cancer (NSCLC) has changed due to liberalized utilization of computed tomography, developments in immunotherapy and targeted treatments, and guidelines encouraging sublobar resections. We analyzed the implications of these advances for surgical procedur…
Aug 2025 DOI 10.14302/oap.jpan-25-5589
Paul ToomeyCorresponding author
Background This study was undertaken to delineate the most predictive pattern at presentation for patients with non-metastatic pancreatic cancer compared to patients with metastatic pancreatic cancer who present to a medium sized hospital. Methods Data were collected at a medium sized hospital from…
Mar 2024 DOI 10.14302/issn.2689-4602.jes-24-4982
Jeffrey O. HendersonCorresponding author
Mammalian Rbm45 is predominately expressed in neuronal tissue and is integral in brain development and neuronal differentiation under physiological conditions. Dysregulation of Rbm45 has been strongly associated with neurodegenerative disorders in humans and can drive hepatocellular carcinoma throug…
Oct 2022 DOI 10.14302/issn.2641-5518.jcci-22-4323
Gracieux Y. FernandoCorresponding author
Introduction Primary sarcomas of the breast are <0.1% of all malignant tumours of the breast. To date, there are 13 major breast sarcoma series in English literature. This study adds to these series characterizing primary breast sarcoma among Philippine patients. Methods All breast biopsies from the…
Jan 2022 DOI 10.14302/issn.2372-6601.jhor-22-4061
Anna B. DanilovaCorresponding author
Background Human malignant cell models which reflect the structural and physiological complexity of tumor tissue are of great importance for preclinical research in oncology. Spheroids/tumoroids derived from solid tumors are of great interest as cellular models mimicking the first vascular-free grow…
Dec 2020 DOI 10.14302/issn.2578-2371.jslr-20-3362
Vaishali V. ShiraleCorresponding author
Background and Aim Gallbladder (GB) cancer is a highly fatal malignancy and approx. 10% new cases are diagnosed every year in India. The GB cancer has poor prognosis due to progressive nature. Understanding of risk factors that lead to GB development is urgently required for better management of the…
Dec 2020 DOI 10.14302/issn.2474-7785.jarh-20-3628
Syiao Wei NgCorresponding author
Hospital Sultanah Aminah, Jalan Persiaran Abu Bakar Sultan, 80100 Johor Bahru, Johor, Malaysia
Multiple primary malignancies especially in the head and neck region is no longer a rare occurrence and the prevalence is increasing. They were described as synchronous when the malignancies present within 6 months of another or metachronous tumors if the subsequent malignancy presents 6 months late…
Jul 2020 DOI 10.14302/issn.2575-1212.jvhc-20-3434
Pamela R.R. MoreiraCorresponding author
Background The mammary glands are the second most common tumor development site in female dogs. One of the ways of staging such tumors is to evaluate the presence or absence of distant metastasis, including in bone marrow. Such findings in human medicine are associated with poor survival of women wi…
May 2020 DOI 10.14302/issn.2641-4538.jphi-20-3289
Thilaga RajendranCorresponding author
Mucoepidermoid carcinoma (MEC) accounts for only 5% of all salivary gland tumors and is most often seen in the parotid glands. MEC occurrence in the larynx is, however, rare. The incidence of primary squamous cell carcinoma (SCC) of salivary glands is also scarce and comprises only about 1.6% of all…
Feb 2020 DOI 10.14302/issn.2689-5773.jcdp-20-3218
Anubha BajajCorresponding author
Trichoepithelioma is a benign, cutaneous neoplasm originating from the hair follicle and is categorized into singular trichoepithelioma, multiple trichoepithelioma and desmoplastic trichoepithelioma wherein desmoplastic trichoepithelioma is cogitated as an exceptional, cutaneous adnexal tumour. Des…
Dec 2019 DOI 10.14302/issn.2575-1212.jvhc-19-3101
Pamela Rodrigues Reina MoreiraCorresponding author
Papillary carcinoma is a mammary neoplasia of women and female dogs characterized by papillary fibrovascular projections lined by epithelial cells. Evaluation on the biology of these tumors can be done by immunohistochemistry through detection of alpha-smooth muscle actin protein in the papillary my…
May 2019 DOI 10.14302/issn.2641-5518.jcci-19-2816
Menon P VarunCorresponding author
Assistant Professor, Department of Oral and Maxillofacial Surgery, Jubilee Mission Medical College and Research Institute, Thrissur, Kerala, India
Basal cell carcinoma (BCC) is the most common type of skin cancer, which arises from the basal layer of the epithelium. It is a slow growing tumor and has a low metastatic potential, it accounts for 70–80% of all cutaneous malignancies in the head face and neck region .Defects near nasal tip and ala…
Feb 2019 DOI 10.14302/issn.2572-3030.jcgb-19-2581
Ashraf KhanCorresponding author
We report the case of a 75 year-old female with past history of ampullary adenocarcinoma presenting with a rapidly enlarging breast mass, initially misclassified on fine needle aspiration as a probable sarcoma, which was ultimately diagnosed as melanoma on resection in the absence of a known cutaneo…
Feb 2019 DOI 10.14302/issn.2574-4496.jtc-19-2657
Luca NicosiaCorresponding author
Image guided ablations might be regarded as a promising effective and safe alternative for treatment of recurrent thyroid cancer in particular in patients with high surgical risk or refusing surgery. Furthermore, image guided ablations seems to represent a promising alternative to surgery or observa…