Search results for “Rats”

About 62 results in articles

Open Access Pub publishes peer-reviewed, free-to-read open-access articles. Showing articles matching Rats — open any to read the full text, or download the PDF or XML.

The Effect of Aqueous Extract of Ocimum gratissium (Linn) on 1, 2 - Dimethyl Hydrazine induced Colon Cancer in Male Wistar Rats

Feb 2020 DOI 10.14302/issn.2577-2279.ijha-20-3180
Ugochukwu UmeakuCorresponding author

Background Colon cancer is one of the leading causes of cancer death world-wide. There is a steady increase in incidence over the past four decades in developing countries. This has been partly attributed to increasingly low intake of vegetables among other causes. Aims Therefore this study aims to…

Interaction Between Ator and Fennel in the Treatment of Obesity in Rats

Oct 2019 DOI 10.14302/issn.2574-450X.jom-19-2852
EH RadwanCorresponding author

Obesity can be defined as a condition of abnormal or excess fat accumulation in adipose tissue, to the extent that health may be impaired. Fennel is one of the oldest spice plants which widely grows in arid and semi-arid and due to its economic importance and pharmaceutical industry usage. This plan…

Effect of a High Fat and High Protein Diet on Exercise-Induced Skeletal Muscle Hypertrophy in Rats

Oct 2019 DOI 10.14302/issn.2379-7835.ijn-19-3011
Takako FujiiCorresponding author

The skeletal muscle mass varies by race. Dietary habits over generations are a factor that influences the skeletal muscle mass, as well as genetic factors. Therefore, we investigated the effects of diets with different macronutrient contents on exercise-induced muscle hypertrophy in rats. Male 4-wee…

Changes in Adult Rats’ Testis structure Induced by Hypothyroidism and Alleviating Role of L-Carnitine

Sep 2019 DOI 10.14302/issn.2577-2279.ijha-19-3026
Abdelmonem Awad HegazyCorresponding author

Background Hypothyroidism is a metabolic disorder affecting the functions of many tissues in the body including the testis. Testis is rich in the polyunsaturated fatty acids content and lacks strong intrinsic antioxidant system making it prone to such oxidative stress. L-carnitine (LC) regulates lon…

Exercise and Vitamin D Supplementation Modify Spleen Morphology in Lean, but not, in Monosodium-Glutamate-Obese Rats

Aug 2019 DOI 10.14302/issn.2578-2371.jslr-19-2819
Maria Guareschi ZoéCorresponding author Laboratory of Endocrine and Metabolic Physiology, University of West Parana (Unioeste), Cascavel, PR, Brazil. +55 4532203257.

An experimental study examines how exercise and vitamin D supplementation affect spleen morphology in lean versus MSG‑obese rats, discussing immunologic implications.

Trigonella Foenum Graecum Extract Benefits on Hematological, Biochemical and Male Reproductive System as a Complementary Therapy with Glimepiride in Treating Streptozotocin Induced Diabetic Rats

Feb 2019 DOI 10.14302/issn.2374-9431.jbd-19-2613
Eman H. RadwanCorresponding author

Diabetes mellitus (DM) is a chronic metabolic disorder. Streptozotocin is a naturally occurring cytotoxic chemical, particularly toxic to the pancreas and insulin producing beta cells in mammals and induces diabetes. Glimepiride is a second generation sulfonylurea, used as second-line or add-on trea…

Beneficial Effects of Fennel (Foeniculum Vulgare) in Treating Obesity in Rats

Jan 2019 DOI 10.14302/issn.2574-450X.jom-18-2484
Eman H. RadwanCorresponding author

Obesity is associated with a number of serious medical complications, which are often referred to as the “insulin resistance syndrome”. The aim of the present study was performed to investigate the possible interaction between a conventional drug used for management of cholesterol and traditional he…

Changes in Rats’ Liver Structure Induced by Zinc Oxide Nanoparticles and the Possible Protective Role of Vitamin E

Oct 2018 DOI 10.14302/issn.2577-2279.ijha-18-2384
Abdelmonem A. HegazyCorresponding author

Background: Oral ingestion of zinc oxide nanoparticles (ZnONPs) may lead to serious liver injury. Vitamin E (VE) is an important antioxidant factor that can reduce such damage. Aim: This study aimed to evaluate the possible changes that could take place in the liver of adult male albino rats after o…

Bisphenol A Down-Regulates The mRNA Expression of Steroidogenic Genes and Induces Histopathological Changes in Testes Of Rats

Mar 2018 DOI 10.14302/issn.2575-1212.jvhc-18-2012
Amal A HalawaCorresponding author

Bisphenol A (BPA) is an endocrine disruptor with a weak estrogenic effect used in industry as a component of food cans. We aimed to study the toxic effects of BPA on mRNA expression of steroidogenic genes and testicular structure in mature male rats. Animals were divided into 3 groups: vehicle contr…

Lipopolysaccharide Prompts Oxidative Stress and Apoptosis in Rats’ Testicular Tissue

Mar 2018 DOI 10.14302/issn.2575-1212.jvhc-18-2013
Amal A HalawaCorresponding author

Lipopolysaccharide (LPS) is a component of the outer membrane of gram negative bacteria. LPS challenging allows switching transcription of proinflammatory cytokines on via over stimulation of Toll-like receptors (TLRs) signaling pathway with subsequent pathogenic inflammatory response. We investigat…

Comparative Study of Hypolipidemic Effects of Momordica Charantia (Karela) with Atorvastatin in Fat Fed Rats

Nov 2017 DOI 10.14302/issn.2576-9383.jhhr-17-1816
Abu Syed Md. MosaddekCorresponding author

Background: Disorders of lipid metabolism are manifested by elevation of the plasma concentration of the various lipid and lipoprotein fractions and the result, predominantly cardiovascular diseases. Lipid research clinic’s coronary primary prevention trial has provided useful information on the red…

Protective Effect of Fennel Oil on Cyclophosphamide Inhibited Spermatogenesis and Induced Oxidative Stress in Albino Rats.

Oct 2017 DOI 10.14302/issn.2576-6694.jbbs-17-1742
Saber A. SakrCorresponding author

Introduction: Cyclophosphamide (CPA) is an anticancer drug .Fennel (Foeniculum vulgare Mill) essential oil is a traditional medicine used against many diseases. Aim. The present work studied the effect of fennel oil against testicular damage and oxidative stress induced by the anticancer drug, cyclo…

Early Glycine Supplementation Re-Establishes Adrenal Catecholamine Secretion in Hypothalamic Obesity Model in Rats but does not Affect Visceral Adiposity.

Jun 2015 DOI 10.14302/issn.2572-5424.jgm-14-604
Ana Eliza AndreazziCorresponding author

Obesity is a worldwide epidemic that features a multifactorial syndrome characterized by a chronic positive energetic unbalance. Neonatal administration of monosodium L-glutamate (MSG) causes lesion on the arcuate nucleus of hypothalamus that led to development of obesity in the adult life in rodent…

Perceptions and Lived Realities of Women’s Engagement in Environmental Conservation in Patriarchal Communities of Northern Uganda: A Qualitative Inquiry

May 2026 DOI 10.14302/issn.2693-1176.ijgh-26-6165
Christine Ruth PiloyaCorresponding author

Background Women’s participation in environmental conservation within patriarchal societies is a critical factor for achieving sustainable development and improved community outcomes. Despite this importance, limited research has examined women’s perceptions of their roles and contributions to envir…

Combined Versus Singular Therapy of Coconut (Cocos nucifera L.) Water and Lime (Citrusaurantiifolia L) Juice in Diabetes Control: Impacts, Implications, and Therapeutic Differences

Dec 2025 DOI 10.14302/issn.2379-7835.ijn-25-5444
Magnus Michael Chukwudike AnyakudoCorresponding author

This study determined and compared the effects of single and combined therapy of coconut water and lime juice in diabetes control in male diabetic Wistar rats. Twenty eight male Wistar rats (weighing: 150-200g) were induced with diabetes mellitus using alloxan monohydrate solution (150mg/kg) and cat…

The Brainstem Auditory Evoked Potential: A Reinterpretation of its Electrogenesis

Sep 2025 DOI 10.14302/issn.2379-8572.joa-25-5687
Nigel A ShawCorresponding author

Depending upon the species, the brainstem auditory evoked potential (BAEP) consists of four or five major high frequency components. According to longstanding doctrine, each wave represents the sequential activation of successively higher nuclei and tracts from the 8th (auditory) nerve to the midbra…

A Review on Monkey Pox: Role of One Health Approach Against Monkey Pox

Oct 2023 DOI 10.14302/issn.2641-4538.jphi-23-4622
Tariku Geinoro AlleyoCorresponding author

The Ortho-poxvirus virus, which causes monkey pox, is a member of the Poxviridae genus. It was initially found in primates. In 1970, the Democratic Republic of the Congo reported the first instance of monkey pox. From there, it spread to a number of countries both inside and outside of Africa. There…

Baroreflex Sensitivity, Cardiac and Kidney Remodeling and Deterioration in Vasoactive Substances Content in Blood in Experimental Model of Renovascular Hypertension. Action of Natural Flavone, Luteolin

May 2023 DOI 10.14302/issn.2574-4488.jna-23-4545
N.A. PapiashviliCorresponding author

This study aimed to analyze pharmacological actions of phenolic compound luteolin on the renal and cardiac hypertrophy, blood pressure (BP), baroreflex sensitivity (BRS), levels of epoxyeicosatrienoic acids (EETs), prostaglandin E-2 (PGE-2) and endothelin-1 (E1) in plasma in the 2 kidney - 1 clip (2…

Histo-Morphological Effect of The Small, Large Intestines and Stomach of Animal Models Treated With Aqueous Extract of Abelmoschus Esculentus

Nov 2022 DOI 10.14302/issn.2641-4538.jphi-22-4235
Kebe E. ObetenCorresponding author

This study investigates the effect of Aqueous extract of abelmoschus esculentus on the microanatomy of the small, large intestine and stomach and the body weight of Wister rats. Twenty-one adults male wistar rats weighing between 100-120 grams were assigned into three groups consisting of seven rats…

Ozone/Oxygen Molecules Exert Mild Oxidative Stress on Testis Mitochondria Isolated from the Rat Testicular Ischemia/Reperfusion Injury

Jun 2022 DOI 10.14302/issn.2471-2140.jaa-21-3911
Morteza IzadiCorresponding author

Testicular ischemia-reperfusion injury is an urgent situation which needs a timely and precise diagnosis for prevention of testis damages. Here in we investigated ozone/oxygen therapy in Testicular Ischemia/Reperfusion Injury. For this purpose, animals (rats) were divided to four groups; control, to…

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