Search results for “Chronic”

About 100 results in articles

Open Access Pub publishes peer-reviewed, free-to-read open-access articles. Showing articles matching Chronic — open any to read the full text, or download the PDF or XML.

Development of a Chronic Obstructive Pulmonary Disease Severity Classification System Using A Japanese Health Insurance Claims Database

Sep 2017 DOI 10.14302/issn.2474-7785.jarh-17-1727
Manabu AkazawaCorresponding author

Background: Healthcare services provided to patients should vary depending on disease severity. However, disease severity bias, a type of selection bias, is a commonly encountered problem in administrative database studies. Herein, we selected chronic obstructive pulmonary disease (COPD), which comm…

Treatment of Chronic Hepatitis B With Tenofovir At The University Teaching Hospital Campus of Lome (Togo)

Aug 2017 DOI 10.14302/issn.2578-2371.jslr-17-1669
Aklesso BagnyCorresponding author

Aims: To describe the clinical, biological and evolutionary features of mono infected patients treated with tenofovir in Togo. Method: It is a descriptive, prospective study. Patients were treated with Tenofovir Disoproxil Fumarate (TDF). The inclusion criteria were: active chronic HBV (HBs Ag-posit…

First Lumbar Treatment of Chronic Mixed Low Back Pain with High Dose Capsaicin 8% Patch

Aug 2017 DOI 10.14302/issn.2688-5328.ijp-17-1581
B. GustorffCorresponding author

Background Capsaicin 8% patch reduces peripheral neuropathic pain. Based on the concept of neuropathic pain (NeP) in mixed low back pain (LBP) it is hypothesized, that an exclusively lumbar capsaicin 8% patch is an effective treatment of mixed LBP. The aim is a proof of this concept and to identify…

Short-Term and Chronic Effects of Aerobic and Resistance Exercise on Sleep in Young Men

Jun 2017 DOI 10.14302/issn.2474-3585.jpmc-17-1506
Clemens DrenowatzCorresponding author

Despite the generally accepted benefits of exercise on sleep there remains limited research on potential differential effects by exercise type. The purpose of the present study was to examine short-term and chronic effects of aerobic and resistance exercise on various sleep quality parameters, as we…

Chronic Pain One to Five Years after Lung Transplantation

Jun 2017 DOI 10.14302/issn.2576-9359.jot-17-1570
A. ForsbergCorresponding author Institute of Health Sciences at Lund University, Sweden.

Chronic bodily pain after lung transplantation has received little attention. Therefore, the aim was to provide a multidimensional assessment of self-reported chronic pain 1-5 years after lung transplantation and its relationship with self-reported psychological general well-being (PGWB) and self-ef…

Internal Jugular Vein and Transverse Sinus Thrombosis as a Complication of a Chronic Ethmoidal Sinusitis

Apr 2017 DOI 10.14302/issn.2470-5020.jnrt-17-1425
Damelan KombateCorresponding author University of Lome (Togo)

Lemierre’s syndrome is rare jugular thrombosis associated with an oropharyngeal infection. The jugular thrombosis is from septic origin. This often happens in young males subjects. We described Lemierre’s syndrome in a 46 year-old man with a chronic ethmoidal sinusitis associated to the left jugular…

Evidence of a Patient Centered Medical Home (PCMH) Improving the Health of Chronically Ill Patients in the Mississippi Delta

Apr 2017 DOI 10.14302/issn.2474-3585.jpmc-17-1449
Wesley L. JamesCorresponding author

Using proprietary data of patient records from four medical clinics in the Mississippi Delta, this research utilizes a natural experiment design to explore if the patient centered medical home (PCMH) has a positive effect on chronic disease maintenance for low SES, majority African-American patients…

The Relationship of Chronic Pain to Attitudes Toward Sucide and Physician-Assisted Suicide among Latino and Non Hispanic White Elders

Mar 2017
Daniel Vélez OrtizCorresponding author

The objective of this study was to examine differences between Latino and White older adults in attitudes toward suicide and physician-assisted suicide in chronic pain scenarios. We used a cross sectional study design at four outpatient care sites in San Antonio, Texas. The study sample included 204…

Differentiating Depression from Apathy in Chronic Kidney Disease: A Prospective Study

Mar 2017 DOI 10.14302/issn.2476-1710.jdt-16-1262
R. SchoenfeldCorresponding author

Background. Emotional deterioration is frequently found in patients with chronic kidney disease, but some patients are affected by depressed mood without fulfilling the criteria of a depressive disorder. Those patients might rather suffer from an apathy symptom. Apathy as a symptom of a medical dise…

Evaluation of Vitamin D Deficiency in Patients with Chronic Liver Disease and Its Clinical Significance

Dec 2016 DOI 10.14302/issn.2379-7835.ijn-16-1381
Bal Kishan GuptaCorresponding author

Introduction: Vitamin D deficiency has been reported highly prevalent in Chronic liver disease (CLD) and there is an emerging interest to explore the relationship of vitamin D deficiency and severity of various types of CLD. Aim: To evaluate vitamin D level in patients with various type of CLD and c…

Bedside Lung Ultrasound in the Assessment of Volume Status in Chronic Hemodialysis Patients

May 2016 DOI 10.14302/issn.2574-4488.jna-15-720
Ghita El BardaiCorresponding author

Introduction: Sonographic B-lines, also known as lung comets, have been shown to correlate with the presence of extravascular lung water. The aim of this study is to assess if chest ultrasound could detect lung water imbibition and its variations induced by dialysis, an experimental model of control…

The Role of BCL-2 and BAK Genes in Chronic Kidney Disease and Haemodialysis Patients

Feb 2016 DOI 10.14302/issn.2572-5424.jgm-15-815
Samah Abd ElhamidCorresponding author

Background: Polymorphonuclear leucocytes are the first line of defence against foreign invaders and constitute the major cell type involved in certain types of acute and chronic inflammatory diseases. Aim of the Work: The aim of the present study was to investigate the changes in expression of BCL-2…

Erlotinib Associated Trichomegaly in a Patient with Chronic Latanoprost Use

Aug 2015 DOI 10.14302/issn.2372-6601.jhor-15-667
CL Cowan JrCorresponding author

Trichomegaly is a known adverse effect with the epidermal growth factor receptor inhibitor (EGFRI) and prostaglandin analogue drug classes. We present a chronic Latanoprost user who developed symptomatic trichomegaly subsequent to initiating an EGFRI medication and believe this case offers evidence…

The Lower Prevalence of Chronic Diseases Risk Factors in Vegetarian Brazilians Subjects – CARVOS Study

Feb 2015 DOI 10.14302/issn.2379-7835.ijn-14-461
Julio Acosta-NavarroCorresponding author

Objective: To investigate the association of meat consumption with self-reported chronic diseases (heart disease, hypertension, diabetes (type I or type II) and dyslipidemia), according to demographic, social and anthropometric variables. Methods: This was a cross sectional study, conducted at the H…

Targeting Cell Metabolism in Chronic Lymphocytic Leukaemia (CLL); Aviable Therapeutic Approach?

Feb 2014 DOI 10.14302/issn.2372-6601.jhor-13-346
Chloe E. ClaphamCorresponding author

Targeting cell metabolism is a therapeutic approach which has been used for the treatment of cancers with high levels of proliferation. Inhibition of metabolic processes in cancer cells has shown synergy with current therapeutic options to reduce refractory disease and relapse. In contrast, chronic…

Incidence and Management of Sural Neuritis Post-Peroneal Tendon Repair – Case Series

Aug 2026 DOI 10.14302/issn.2641-5518.jcci-26-6134
Ashraf KhafagaCorresponding author

Background Sural neuritis is a recognized and common complication resulting from iatrogenic injury, postsurgical or posttraumatic fibrosis, traction injury, or chronic nerve compression. Previously in a case series by Stockton and Brodsky, sural neuritis was reported as a complication in 16.6% of th…

Pnpla3/Adiponutrin Deficiency in Mice Does Not Contribute to Steatohepatitis, Fibrosis or Cholestatic Liver Injury

Mar 2026 DOI 10.14302/issn.2641-9181.ijnr-25-5844
Michael TraunerCorresponding author

A sequence variation (I148M) in the patatin-like phospholipase domain-containing protein 3 (PNPLA3) gene has been linked to metabolic dysfunction-associated steatotic liver disease (MASLD) and the progression of MASLD and other chronic liver diseases towards fibrosis and cancer. To elucidate the rol…

Activation of Transcription Factor EB Protects Against Proinflammatory Insults Through NF-κB Inhibition in Keratinocytes

Feb 2026
Hui XingCorresponding author

Keratinocytes are pivotal in mediating cutaneous inflammation. Identifying anti-inflammatory factors within these cells holds promise for developing novel therapeutic strategies to manage skin inflammation. Transcription factor EB (TFEB) has recently emerged as a key regulator linking cellular energ…

Interactions Between Natural Nuclear Reactors and Microbial Evolutionary Processes

Feb 2026 DOI 10.14302/issn.2689-4602.jes-25-5926
Chuck EasttomCorresponding author

The impact of ionizing radiation on genetic change is well established, yet the extent to which naturally occurring radiation fields have influenced evolutionary trajectories remains incompletely understood. This study examined correlations between microbial evolution and the radiation and geochemic…

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