Overview
Bladder cancer is a malignancy arising from the tissues of the urinary bladder, most commonly the urothelium that lines the bladder wall. The predominant histological type is urothelial (transitional cell) carcinoma, with squamous cell carcinoma and adenocarcinoma occurring less frequently. The hallmark presenting feature is painless hematuria, sometimes accompanied by urinary frequency, urgency, or pain on voiding. A central clinical distinction is between non-muscle-invasive disease, confined to the mucosa and lamina propria, and muscle-invasive disease that penetrates the detrusor muscle, since this separation governs prognosis and treatment. Established risk factors include tobacco smoking and occupational exposure to aromatic amines and other industrial chemicals, while chronic irritation and certain infections contribute in some settings. Diagnosis relies on cystoscopy, urine cytology, imaging, and transurethral resection with histopathological staging and grading. Management is stage-dependent and may combine transurethral resection, intravesical therapy, radical cystectomy with urinary diversion, systemic chemotherapy, radiotherapy, and immunotherapy. Surgical reconstruction such as ileal conduit diversion can itself give rise to later complications. Because non-muscle-invasive tumors recur frequently, long-term surveillance is integral to care, and ongoing research addresses molecular characterization, biomarkers, and bladder-preserving strategies.
Research published in this journal
9 peer-reviewed articles, ranked by relevance. Each links to its DOI.
The Role of Biogenic Amines in Nutrition Toxicology: Review
Evolution of the Solid Human Tumor Cells Properties in Various Experimental Systems in Vitro
Delayed Laparoscopic Repair of Bladder Injury with Vesico Cutaneous Fistula in Fracture Pelvis
Oxidative Telomere Attrition, Nutritional Antioxidants and Biological Aging
Advancements in Cancer Gene Therapy: A Comprehensive Review
Expression of Estrogen Receptor β in Hypothalamic Stem Cells
Drug Design Progress of In silico, In vitro and In vivo Researches
Giant Ileal Conduit Stone: Feasibility of Endoscopic Lithotripsy: A Case Report and Review of Literature
How this research is being cited
The 9 articles above have been cited 35 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Nov 2026.
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2027 · Food Control
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2026 · Microchemical Journal
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2026 · Microchemical Journal
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2026 · Food Control
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2026 · Talanta
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2026 · Food Control
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2026 · Food Control
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Serkan Erdemir et al. · 2025 · Talanta: The International Journal of Pure and Applied Analytical Chemistry
A sample of recent works citing this journal's research on Bladder Cancer, linking to each citing work.