Research Topic · Peer-Reviewed

Growth Factors

Growth factors are secreted signaling proteins that regulate cell proliferation, differentiation, survival, and migration, and they are central to embryonic development, tissue growth, and repair. Acting through binding to specific cell-surface receptors, they activate intracellular signaling cascades that coordinat…

Curated from this journal's research 📚 12 peer-reviewed articles cited Cited 138× across the literature 🔖 ISSN 3070-5657

Overview

Growth factors are secreted signaling proteins that regulate cell proliferation, differentiation, survival, and migration, and they are central to embryonic development, tissue growth, and repair. Acting through binding to specific cell-surface receptors, they activate intracellular signaling cascades that coordinate the behavior of responding cells, and distinct families, including epidermal, fibroblast, transforming, and platelet-derived growth factors, exert specialized effects on developmental patterning, morphogenesis, and organ formation. In the embryo, growth-factor gradients and signaling interactions govern induction, lineage specification, and the differentiation of progenitor populations, while in postnatal tissue they drive wound healing, angiogenesis, and regeneration. Imbalances in growth-factor signaling are implicated in developmental defects, impaired healing, aging, and tumorigenesis, and controlled growth-factor delivery is important in tissue engineering. Research relevant to this area examines molecular control of human embryonic development, growth-factor signaling in tumor cell biology, scaffolds and platelet-rich fibrin for bone regeneration, wound-fluid effects on healing in three-dimensional wound models, transcription-factor binding and signaling in disease, hair-follicle and adipose-tissue biology, low birth weight and vascular phenotypes, and root-system responses to stress. The journal publishes peer-reviewed studies on growth-factor signaling and its role in development, differentiation, tissue repair and regeneration, and disease across biological systems.

Research published in this journal

12 peer-reviewed articles, ranked by relevance. Each links to its DOI.

How this research is being cited

The 12 articles above have been cited 138 times in the scholarly literature. Citation data via OpenAlex and Crossref, updated Nov 2026.

A sample of recent works citing this journal's research on Growth Factors, linking to each citing work.

Editorial oversight

Curated from peer-reviewed research published in Journal of Embryology (ISSN 3070-5657).

Journal editorial board
jianliang jin · China Alexander Ereskovsky · France Cristina Eguizabal · Spain

This page summarises published research for orientation; it is not medical or professional advice.